抄録
The reactions of ethylenediamine (ED) and formaldehyde (FA) in the alumina-packed bed reactor were studied. Methylpyrazine was obtained as the main product, and a small amount of dimethylpyrazine was also obtained. This reaction mechanism is yet unknown, and a statistical method was employed for the determination of optimum condition. The first part of the investigation consisted of 24 factorial design. Four variables were chosen-reaction temperature (A), catalyst weight (B), molar ratio of reactants (C), and the amount of water added (D). In the analysis of variance, all factors except (B) were significant at the 5% level. The interaction between (A) and (C) was checked in a wider range. Through experiments in the direction of the steepest ascent based on the first-order response function, it was found that the yield of methylpyrazine dropped suddenly beyond 410° and it was concluded that the optimum condition are follows : temprature 410°, catalyst weight, 21.92 g, molar ratio FA/ED=2.78, and dilution water 30.49 times mole, which gave the maximum yield of 42.5%.
