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Volume 21 (2006)
- Issue 6 Pages 592-
- Issue 5 Pages 492-
- Issue 4 Pages 388-
- Issue 2 Pages 102-
- Issue 1 Pages 18-
Volume 21, Issue 6
Displaying 1-5 of 5 articles from this issue
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Feature articles “Nanobioscience” Editor : Teruo Okano
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new polymeric materials for DDSMasatoshi Kidowaki, Toshiyuki Kataoka, Kohzo Ito2006 Volume 21 Issue 6 Pages 592-598
Published: 2006
Released on J-STAGE: March 30, 2007
JOURNAL FREE ACCESSWe reviewed the fundamental aspects and applications of slide-ring materials as new polymeric materials for DDS. The slide-ring gel is one of the slide-ring materials using sliding features most effectively and has movable cross-linking junctions. As a result, it exhibited mechanical properties quite different from chemical gels, rather close to biomaterials. The small angle neutron scattering studies of the slide-ring gels revealed that the pulley effect relaxed the inhomogeneous structure in the slide-ring gels. In addition, we introduced the sol-gel transition of methylated polyrotaxane as a new thermoreversible DDS system. Finally, we discussed the application of the slide-ring materials to DDS with the future view.View full abstractDownload PDF (1426K) -
Ichiro Yamashita2006 Volume 21 Issue 6 Pages 599-607
Published: 2006
Released on J-STAGE: March 30, 2007
JOURNAL FREE ACCESSA new bottom-up process for the fabrication of inorganic nanostructure is proposed. A template protein supramolecule for the single electron transistor and a large 2D ferritin crystal were successfully produced. Floating gate memory produced employing this method shows clear memory effect.View full abstractDownload PDF (2128K) -
Takashi Funatsu2006 Volume 21 Issue 6 Pages 608-614
Published: 2006
Released on J-STAGE: March 30, 2007
JOURNAL FREE ACCESSFunctions and interactions of protein molecules are major issues in the post-genome age. Single-molecule imaging techniques for these studies and on-chip biomolecular or organelle sorter to analyze their components are introduced.View full abstractDownload PDF (1489K) -
Masayuki Yokoyama2006 Volume 21 Issue 6 Pages 615-622
Published: 2006
Released on J-STAGE: March 30, 2007
JOURNAL FREE ACCESSNano-sized drug carriers have been actively studied and developed in the field of DDS in much earlier years than the year 2000 when a famous nanotechnology initiative program was presented by the US government. The reason for this preceding activity concerning nanotechnology is the fact that advantages and significance of the use of nano-sized drug carriers had been well known and recognized until 1990's in the DDS field. Furthermore, developments in preparation technology of the nano-sized carriers in 1980's and 1990's are the other reason.
In this review, advantages and significance of the nano-sized carriers are explained first, followed by classification of the carriers. In the last chapter, recent developments and future perspectives of each class of the carriers are concisely described as well as related two topics (nano-medicine and molecular imaging) are briefly introduced.View full abstractDownload PDF (1135K) -
Masayuki Yamato2006 Volume 21 Issue 6 Pages 623-626
Published: 2006
Released on J-STAGE: March 30, 2007
JOURNAL FREE ACCESSIn order to realize full-blown regenerative medicine that is expected to achieve permanent care, a wide variety of breakthroughs would be required. In addition, ES cells have been also focused as another cell source in clinical settings following early clinical success with somatic stem cells. Here, the current statuses of regenerative medicine and ES cell research are summarized, and the expectation for nanotechnology in this field is described.View full abstractDownload PDF (693K)
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