The review article shows the characteristic of oral biofilm infectious diseases. Oral bacterial species possess biofilm-forming activity on the surface of tooth, periodontal region, dorsum of tongue, buccal epithelium, dental implant, and denture as a unique ecosystem. Dental plaque is known as the typical biofilm consisting the community with various kinds of bacteria. Our studies have suggested that oral biofilm organisms may play a role in the etiology of various kinds of systemic diseases. We examined oral bacteria in samples from atherosclerotic lesions including cardiovascular disease. Treponerna denticola 16S rRNA and the antigen were found in 6 out of 26 DNA samples from the formalin-fixed, paraffin-embeded atherosclerotic lesions obtained during surgery. but not in any of the 14 non-diseased aorta samples. We also detected periodontal disease-associated bacteria in samples of cardiovascular diseases. We found that oral bacteria are able to trap Helicobacter pylori that is known to cause gastritis and peptic ulcer disease, but inhibited H. pylori growth. Periodontopathic Campvlobacter rectus strains possess cross-reactive antigens including heat shock proteins with H. pylori strains suggesting that antigens of C. rectus may be related to the induction of immunopathological responses. We also found the relationship between paeriodontal disease-associated bacterial heat shock proteins and pustulosis palmaris et plantaris. The significance of oral care for elderly requiring nursing care was demonstrateel. We also discussed the denture and implant biofilms in the review.

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[in Japanese]

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[in Japanese]

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Recently, the number of patients with unidentified complaints has increased. Since occlusal disharmony is a cause of unidentified complaints in some patients, investigation of the relationship between occlusion and posture is important. In this study, we investigated improvement in occlusion with changes in posture. As a result, improvement in systemic symptoms was a two-stage process, in which improvement in the head position was obtained in the first stage. and improvement in the right rotation posture was obtained in the second stage. Furthermore, it was revealed that posture related to occlusion was classified into posture when diseases occurred, and habitual posture due to life-style and work circumstances.

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Slavicek, Professor Emeritus at Vienna University, proposed that nocturnal bruxism functions as stress management. However, there is little scientific or objective evidence to support his proposition. If bruxism does play a role in stress management, a decrease of the sympathetic nerve activity and an increase of the parasympathetic nerve activity will be observed during the act. In this study, the role of grinding in stress management was determined.
Qualification/quantification analysis of grinding, we used a computer axiograph. Autonomic function assessment BRS (parasympathetic nerve activity) and low frequency component represent-ing blood pressure (sympathetic nerve activity) were calculated by MemCalc.
The sympathetic nerve component was significantly lower and BRS significantly higher during grinding than at rest in the normal group. In contrast, the sympathetic nerve component was significantly higher and BRS significantly lower during grinding than at rest in the abnormal group.
In this study, grinding was associated with a decrease in the sympathetic nerve component and increase of BRS in the normal group. This suggests that nocturnal grinding might play a role in stress management.

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[in Japanese]

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