Osseointegration of implant fixtures in bone tissues is an important factor for the prognosis for implant treatment. One rational approach for implant treatments is to shorten the period of necessary osseointegration. It has been demonstrated that ultra short wave (USW) stimulates bone modeling and remodeling, and accelerates the bone regeneration process. Based on these facts, an assumption can be made that USW can be applied for implant treatment to accelerate osseointegaration. The goal of this study was to examine the effects of USW on osseointegration of titanium implants using rat tibiae. For this purpose, histological and bone morphometoric analyses were carried out in rat proximal tibiae installed implant fixtures. Thirty Sprague-Dawlay rats had titanium implants installed on both sides of the proximal tibiae. The rats in the USW group received USW (27.12MHz for 20 min) 3 times a week, while the control group had no USW irradiation. At two and four weeks after implant operation, removal torque test demonstrated that the values in the USW group were much higher than those in the control group. The specimens of the tibiae in the USW group revealed a larger amount of new bone formation around the fixtures than those in the control group at 2 weeks after the operation. Though the mature lamellate bone tissues could be seen around the fixtures in the USW group at 4 weeks after the operation, little mature bone tissue was observed in the control group. Furthermore, the number of osteoclasts present in bone tissues surrounding the fixtures in the USW group was significantly higher than those in the control group 4 weeks after the operation. These results indicate that USW irradiation stimulated bone formation and increased bone remodeling in the bone tissue around the implant fixtures, and that USW can be a useful device for implant treatment.
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