Skin Research, 16: 2-3, 2017

View full abstract

Two male patients, 18 years old and 15 years old, presented with coccygeal nodules of 50×30mm and 60×30mm in diameter, respectively. The two patients were thinly built and had kyphotic tendencies. Both patients underwent surgical excision of the nodules under local anesthesia. Histopathological examination of the nodules revealed thickened epidermis and marked dermal collagen hyperplasia. The nodules have not recurred during two years of follow-up after the excision. Both nodules were expected to be produced by physical exercise (sit-ups) or bicycle riding and their inappropriate sitting position. On determining the etiological factors, the material of the chair and the patient's sitting posture should be taken into account.Skin Research, 16: 80-83, 2017

View full abstract

A 62-year-old man noticed a subcutaneous tumor on his scalp approximately one year ago. As only temporal flattening could be achieved following aspiration of its contents, the tumor was resected under local anesthesia. Histopathologically, the tumor was composed of multilocular cysts, whose lumen consisted of columnar cells with eosinophilic cytoplasm. Decapitation secretion and papillary projection of luminal cells into the lumen was noted. There was also a luminal layer of clear cells. The cells were positive for staining with GCDFP-15 and CK7. We considered cystic tumors of apocrine nature, such as apocrine cystadenoma, apocrine hidrocystoma, or apocrine papillary cystadenoma, and diagnosed this tumor as apocrine cystadenoma based on its histological features.Skin Research, 16: 84-87, 2017

View full abstract

We performed cumulative skin irritation and skin sensitization tests for the nano-capsulated emu oil-based moisturizer “Emurance EE Serum” which was emulsified with lecithin in order to evaluate its skin safety. The participants were 27 healthy people (aged 20-60 years), who did not have skin diseases such as atopic dermatitis or eczema. The moisturizer Emurance EE Serum is a cosmetic in which 2% emu oil was dissolved through the lecithin-emulsification method. This is the first use of the lecithin-emulsification method for an emu oil-based moisturizer in Japan. The cumulative skin irritation test was performed by attaching a closed patch of the sample to the paravertebral area of the participants for 24 hours, and this test was repeated nine times over a period of three weeks. The skin sensitization test was performed from 10 to 14 days after the cumulative skin irritation test. The patch was attached at the same location for 24 hours, and the skin was observed immediately after removal of the patch and 24 hours later. Positive reactions were not noted in any of the participants. Therefore, the moisturizer Emurance EE Serum can be safely used on the skin.Skin Research, 16: 88-92, 2017

View full abstract