The word “Waon” means “soothing and warmth”. Waon therapy is an innovative treatment developed in Japan that meets the desired requirements such as safe, effective, low cost and non-invasive. It brings comfortable sweating and improve mood and complexion. It has demonstrated significant expression of nitric oxide from the vascular endothelium, resulting in an improvement of cardiovascular endothelial function and promotion of blood flow to organ of the whole body. Moreover, it has clarified various effects such as capillary angiogenesis, antioxidant effect, increased parasympathetic nerve activity, decreased sympathetic nerve activity, mental/physical relaxation and immunity enhancement. Waon therapy is effective for various intractable diseases such as severe heart failure and severe lower limb ischemia etc. In 2020, it approved for a new national insurance listing in the treatment of severe heart failure. In near future, insurance coverage hope to be realized to lower limb ischemia, chronic fatigue syndrome and fibromyalgia. As the next deployment, Waon therapy is highly expected to use in super-aging society in various ways. For example, comprehensive rehabilitation, elderly care, frailty prevention, improvement of QOL, healthy longevity and palliative care etc. Waon therapy brings long life happiness.