The problem of osteoporosis was studied in sixty-two hemiplegics with a mean age of 63.5 years old and median duration of illness of 8.0 months (1 to 144 months). Systemic osteoporosis was examined by means of quantitative CT evaluation of bone mineral content (q-CT) of the third lumbar vertebra. Local osteoporosis of the hand and femoral neck was evaluated by microdensitometry method of the second metacarpal bone (MD method) and Singh index respectively. The following results were obtained.
1) The bone mineral content of the third lumbar vertebra as evaluated by q-CT was decreased in 17% of cases when compared to normal values. On the basis of multiple regression analysis, it was significantly correlated with age, but not with sex, degree of motor paralysis, duration of illness, mental scale and Barthel index.
2) The number of cases with smaller MCI and ΣGS/D (the parameters of osteoporosis in MD method) on the affected side as compared to the sound side was significantly greater in cases with severe paralysis of the hand.
3) Singh index was smaller on the affected side than on the sound side in cases with moderate to severe paralysis of the lower extremity.
Our study confirmed the presence of local osteoporosis on the affected side of the hemiplegics, which was related to the degree of motor impairment. Further study is needed to clarify the mechanism of osteoporosis in the hemiplegics and its therapeutic implications.
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