The guide wire of the 22-G Safe guide
® becomes occasionally bent and/or locked during insertion. We compared the 22-G Safe guide
® and 20-G Safe guide
® in terms of usefulness and incidence of complications during central venous catheterization. One hundred and twenty patients were randomly allocated into two groups, 60 patients in the 22-G Safe guide
® group and 60 patients in the 20-G Safe guide
® group. Central venous catheterization was performed by puncturing the right jugular vein. Back flow of blood during withdrawal of the needle appeared significantly greater with the 20-G Safe guide
® than with the 22-G Safe guide
® (I% vs 6.7%, p<0.05 ). The incidence of bending and locking during the introduction of the wire was not significant between the 22-G Safe guide
® group (16.6 %) and the 20-G Safe guide
® group (13.3%). No guide wires of 20-G Safe guide
® became bent at the insertion point during the introduction of the dilator, while 6.6% of the guide wires of the 22-G Safe guide
® became bent. The incidence of complications (accidental puncture of the carotid artery) was not significant between the two groups. In conclusion, the 22-G Safe guide
® was more useful and safer than the 20-G Safe guide
® except for the bending of the guide wire. The guide wire of the 22-G Safe guide
® was expected to be more resistant to the bending and locking which occurred during insertion.
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