A 10-year-old spayed female Spitz was referred to our center for the confirmation and treatment of a recurrent cervical mass, which was previously diagnosed as oncocytoma. Pulmonary edema was identified by chest radiographic imaging. During the examination, the dog developed severe respiratory distress. After intubation, positive pressure ventilation and positive end-expiratory pressure were employed, and the pulmonary consolidation was resolved within two days. Therefore, negative pressure pulmonary edema related to the cervical mass was suspected. Permanent tracheostomy was performed to reduce upper airway narrowing caused by the unresectable mass on day 3. The dog was discharged on day 13 and survived for 312 days after surgery.

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A 13-year-old female Welsh Corgi was treated for refractory glaucoma. Ultrasound examination suggested an intraocular tumor. Computer tomography (CT) revealed hyperattenuating lesions in the affected eye. Enucleation was performed and intraocular osteosarcoma was diagnosed by histopathology. The tumor recurred at the surgical area on the 46th day after surgery. Intracranial tumor invasion was suspected based on clinical signs, and the dog was euthanized. Based on this case, CT scanning may be useful for detecting primary intraocular osteosarcoma. These tumors may show malignant behavior and severe local invasiveness compared with other types of intraocular tumors.

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A 6-year-old castrated male Yorkshire terrier weighing 2.0 kg was referred with progressive inspiratory stridor. Radiographic evaluation of the cervical region demonstrated two soft-tissue densities involving the pharynx and larynx. Oral and laryngeal examinations were performed under general anesthesia. Because the pharyngeal mass obstructed the airway, a tracheostomy tube was inserted through a tracheotomy. Computed tomography images showed two separate masses of the pharynx and larynx. Rhabdomyosarcoma was diagnosed via histopathology of the pharynx. A permanent tracheostomy securing the airway and palliative radiation therapy were performed. Both tumors shrunk after palliative radiation therapy, and there was symptomatic improvement. Twenty-six months after surgery, the laryngeal tumor increased in size, and was again successfully treated by palliative radiation therapy. Forty months after permanent tracheostomy, there have been no signs of respiratory distress, local recurrence, or metastatic disease. Canine pharyngeal and laryngeal rhabdomyosarcoma has the potential to respond to radiation therapy.

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Primary renal hemangiosarcomas were treated by nephrectomy in two dogs. The first dog exhibited hematuria associated with a right renal mass, which improved after nephrectomy. The dog died 75 days after surgery with splenic and hepatic metastases. The second dog suffered continuous hematuria due to a large left renal mass, which was treated with nephrectomy followed by carboplatin treatments. Hematuria resolved after surgery. The dog died 197 days after surgery with metastases to both lung and skin. In the both cases, a recurrence at the primary site was not observed during the follow-up period. Nephrectomy is considered effective for the local control of renal hemangiosarcoma in dogs, but post-surgical adjuvant chemotherapy may be necessary to prolong survival.

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