A female spayed domestic shorthair with an estimated age of 8 to 10 years was presented with chief complaints of cervical ventroflexion, seizure, and collapse. Blood examination revealed hypokalemia, and abdominal radiography and ultrasound examination showed a mass cranial to the right kidney, possibly originating from the right adrenal gland. Medical treatment for hypokalemia resulted in minimal improvement of the clinical signs. Additional examination revealed a high aldosterone level and low serum renin activity. The mass was removed and histopathologically diagnosed as an adrenal adenocarcinoma. Based on these results, the cat was diagnosed with primary aldosteronism secondary to an adrenal adenocarcinoma. The cat exhibited rapid postsurgical improvement in the clinical signs and hypokalemia. The cat survived for an additional 4 years 5 months.

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An 8-year-old neutered male golden retriever was presented for evaluation of dysuria. The dog showed perineal swelling on physical examination. Retrograde positive-contrast urethrography revealed a tennis ball-sized filling defect in the perineal urethra, suggesting a urethral tumor. Surgical removal of the mass was scheduled to relieve the dysuria. The urethral mass was revealed via a perineal midline approach and removed with a surrounding portion of the urethra. The external urethral orifice was reconstructed. The mass was histopathologically diagnosed as a leiomyoma. The dog’s postoperative recovery was favorable and uneventful.

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Primary vertebral osteosarcoma (PVO) is a rare disease in dogs, and few reports have described the treatment or prognosis of canine PVO. This report describes three dogs with PVO treated with debulking surgery. The first case involved a 12-year-old 10-kg female mongrel dog with progressive hind limb paralysis due to PVO at the L3 vertebra. Debulking surgery resulted in transient resolution of the paralysis, but the dog was euthanized 48 days after surgery because of progression of her neurological deficit. Case 2 involved an 8-year-old 15-kg female mongrel dog with acute hind limb paralysis due to PVO at the T12 vertebra. Debulking surgery followed by six carboplatin treatments resulted in maintenance of ambulatory function for more than 7 months after surgery. Case 3 involved a 10-year-old male Pembroke Welsh corgi with acute hind limb paralysis likely associated with PVO at the T5 vertebra. The dog’s neurological deficit did not improve after debulking surgery and he died 27 days later. Debulking surgery may be of value in dogs with PVO as a diagnostic or palliative procedure, but the postsurgical prognosis seems to vary among individuals.

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