Japanese Journal of Veterinary Anesthesia & Surgery
Online ISSN : 2189-6631
Print ISSN : 2189-6623
ISSN-L : 2189-6623
Volume 48, Issue 1+2
Displaying 1-3 of 3 articles from this issue
Original Article
  • Atsuko KOJIMOTO, Teruo ITOH, Kazuyuki UCHIDA, James CHAMBERS, Hiroki S ...
    2017 Volume 48 Issue 1+2 Pages 1-8
    Published: 2017
    Released on J-STAGE: March 31, 2018
    JOURNAL FREE ACCESS
    We investigated the clinical features and treatment results of 24 cats with mast cell tumors (MCTs), including cutaneous (c-MCT, n=17), splenic (s-MCT, n=2), and simultaneous cutaneous and splenic types (cs-MCT, n=5). Cutaneous lesions were treated by surgical excision or glucocorticoid therapy, and six of seven splenic lesions were treated by splenectomy. Of the 22 cats with c- or cs-MCT, six cats (four with c-MCT, and two with cs-MCT) had one to three distant recurrences (at a skin site distant from the original site) after initial treatment. Of the 31 c-MCTs in these 22 cats, eight were treated with glucocorticoid therapy, which led to complete remission of seven c-MCTs (88%); the other 23 c-MCTs were surgically excised, with only one (4%) recurrence at the surgical site. Although eight of 24 cats (33%) developed recurrent lesions, tumor-related death only occurred in one cat with cs-MCT (4%) during the follow-up period (range 30 to 2,364 days, median 537 days). These results suggest that both surgery and glucocorticoid therapy were effective in local control of c-MCTs, and that long-term survival can be expected, even in cats with s-MCTs who have undergone splenectomy.
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Brief Note
  • Atsuko KOJIMOTO, Teruo ITOH, Kazuyuki UCHIDA, James CHAMBERS, Hiroki S ...
    2017 Volume 48 Issue 1+2 Pages 9-13
    Published: 2017
    Released on J-STAGE: March 31, 2018
    JOURNAL FREE ACCESS
    An 8-year-old spayed female Jack Russell Terrier presented with acute bacterial peritonitis. Laparotomy revealed two jejunal perforation sites, both of which were surgically resected. Histopathology and immunohistochemistry revealed that both lesions were histiocytic sarcomas. The dog recovered uneventfully, and received seven treatments of intravenous carboplatin. There were no recurrences of visible tumors or perforative peritonitis until the dog died at postoperative day 185 due to chronic diarrhea of unknown causes. This is the first report of canine primary jejunal histiocytic sarcoma; the present case suggests that spontaneous perforation may occur even in small lesions for which surgical resection is useful.
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  • Kensuke FURUTA, Shunji ISHII, Ayaka ARAI, Saori OKUTOMI, Iwao SAKONJYU
    2017 Volume 48 Issue 1+2 Pages 15-20
    Published: 2017
    Released on J-STAGE: March 31, 2018
    JOURNAL FREE ACCESS
    Two young dogs (a 4-month-old male French Bulldog, and a 4-month-old male Akita) presented with severe systemic pain involving bone resorption and multiple fractures. Other diseases characterized by bone fragility were excluded by clinical examinations, and so the dogs were provisionally diagnosed with osteogenesis imperfecta. In both dogs, the systemic pain resolved within 1 week after the start of diagnostic treatment with oral bisphosphonate (0.5–1.0 mg/kg), and bone unions were achieved in the multiple fractures. The two dogs have been in good physical condition without further fractures for 27 and 22 months, respectively. The definitive diagnosis of canine osteogenesis imperfecta is currently difficult because it requires genetic diagnosis. Diagnostic treatment with oral bisphosphonate is effective in alleviating potentially fatal symptoms in dogs with suspected osteogenesis imperfecta.
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