The Japanese Journal of Nephrology
Online ISSN : 1884-0728
Print ISSN : 0385-2385
ISSN-L : 0385-2385
Volume 44, Issue 1
Displaying 1-6 of 6 articles from this issue
  • 2002 Volume 44 Issue 1 Pages 1-17
    Published: January 25, 2002
    Released on J-STAGE: July 05, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese]
    2002 Volume 44 Issue 1 Pages 18-28
    Published: January 25, 2002
    Released on J-STAGE: July 05, 2010
    JOURNAL FREE ACCESS
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  • Kazuhiko NIIMI, Ken IDE, Noboru TSURU
    2002 Volume 44 Issue 1 Pages 29-33
    Published: January 25, 2002
    Released on J-STAGE: March 01, 2011
    JOURNAL FREE ACCESS
    During the period of 27 years from 1974 to 2000, acute episodes were studied retrospectively in 130 patients under 14 years of age with poststreptococcal acute glomerulonephritis (PSAGN) . PSAGN cases have a variable clinical presentation from asymptomatic to severe oliguric acute renal failure (ARF). Proteinuria is nearly always present, but is less than 3.5 g/day. Nephrotic syndrome (NS) is not commonly observed in PSAGN. Among 130 patients, 5 cases had NS with ARF. The present study investigated a spectrum of NS with ARF and the significance of clinical features in PSAGN.
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  • Tomonar OKADA, Toshiyuki NAKAO, Hiroshi MATSUMOTO, Hiromi HIDAKA, Maki ...
    2002 Volume 44 Issue 1 Pages 34-43
    Published: January 25, 2002
    Released on J-STAGE: March 01, 2011
    JOURNAL FREE ACCESS
    We investigated 1) the association between serum albumin levels (Alb) at the initiation of dialysis and survival after a mean follow-up period of 30.1 ±23.1 months following the commencement of chronic dialysis, and 2) the factors associated with hypoalbuminemia at the initiation of dialysis in diabetic patients with end stage renal failure (ESRF). A hundred and thirty diabetic patients who were initiated on chronic dialysis in our department between January 1992 and November 2000 were studied. Alb and some variables were collected at 12, 6, 3, and 1 month before the initiation of dialysis ( -12, - 6, - 3, -1 M), at the initiation of dialysis (0 M), and 1, 6, and 12 months after commencing chronic dialysis (1, 6, 12 M) . Multivariate logistic regression analysis showed that hypoalbuminemia (less than 3 g/dl) at 0 M was significantly associated with an increase in urinary protein excretion per 1 g/day during -12 M and -1 M and total blindness due to diabetic retinopathy (Odds ratio 1.41, 8.83, p=0.01, 0.03). Cox's proportional-hazard model demonstrated that a decrease in Alb per 1 g/dl at 0 M was significantly associated with survival (Hazard ratio 3.69, p=0.03, adjusted age, sex, mode of dialysis, and urinary protein excretion during -12 M and -1 M). In addition, a decrease in Alb between -1 M and 0 M was significantly associated with elevated C-reactive protein at 0 M and a decrease in hematocrit between -1 M and 0 M. In conclusion, hypoalbuminemia at the initiation of dialysis, from any cause other than proteinuria, was associated with a poor prognosis after commencing chronic dialysis in diabetic ESRF patients.
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  • Shizue SEKINE, Wako YUMURA, Yuko TANAKA, Shinya SUGANUMA, Takako ONUKI ...
    2002 Volume 44 Issue 1 Pages 44-49
    Published: January 25, 2002
    Released on J-STAGE: July 05, 2010
    JOURNAL FREE ACCESS
    We report a rare case of nephrotic syndrome in an elderly woman with positive antineutrophil cytoplasmic antibody (ANCA) . The patient was 81 years of age and had a history of interstitial pneumonia. She was diagnosed rheumatoid arthritis (RA) at admission. Rapidly progressing renal damage was found with mild microscopic hematuria and positive ANCA. The renal biopsy findings indicated membranous nephropathy. Neither gold nor anti rheumatic drugs had been previously administered. She may have had an RAspecific membranous nephropathy. Crescentic formation was not clear. With hematuria, the leukocyte infiltration in the capillary lumen and the change in epithelial cells of Bowman's capsules would be histological findings suggesting ANCA-associated nephritis. This is a rare report on membranous nephropathy in an RA patient with ANCA associated nephritis.
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  • Hiroyuki TERAWAKI, Takahide SUZUKI, Kazunobu YOSHIMURA, Toshio HASEGAW ...
    2002 Volume 44 Issue 1 Pages 50-53
    Published: January 25, 2002
    Released on J-STAGE: July 05, 2010
    JOURNAL FREE ACCESS
    A 73-year-old woman with chronic renal failure developed generalized muscular weakness and pain 6 days after the start of allopurinol treatment (200 mg/day) . Routine laboratory tests revealed elevated levels of serum creatine kinase, and the patient was clinically diagnosed as rhabdomyolysis, due probably to severe myositis. A high level of serum oxipurinol, the chief active metabolite of allopurinol, was also revealed. The muscular weakness was relieved in seven weeks with intermittent hemodiafiltration.
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