The present study was designed to assess QTc and the relationship between the QT and the RR intervals in beagle dogs. Standard limb lead ECGs were recorded using a canine autoanalyzing electrocardiograph in 77 dogs.
The results obtained were as follows ;
1. The RR intervals had a large variation in 6-second ECG tracings, while the variation in the QT interval was negligible on each ECG.
2. Significant positive correlations were observed between any type of RR intervals (longest, shortest, mean and just before the QT interval measured by the autoanalyzing ECG) and the QT interval in 70 dogs. The greatest correlation was seen between the mean RR interval and the QT interval.
3. Repeated ECG recording in 7 dogs revealed a significant positive correlation between the RR and the QT intervals in 6 dogs, and the greatest correlation was also between the mean RR interval and the OT interval among the 4 defined RR intervals. One dog in which a correlation was not found had a high CV-RR value and showed a ventricular premature beat on ECG.
4. To address the problem that the QT interval value corrected for RR interval (QTc=QTc
60) is larger than the uncorrected value in many dogs, comparisons of QTc
60 and QTc
100 were made. The QTc
100 values were closer to the uncorrected QT intervals than were the QTc
60 value.
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