Advances in Animal Cardiology

The Weighing Monotherapy Using Anticoagulant Agent and Combined Therapy Using Thrombolytic Agent in Cats with Aortic Thromboembolism

Yuto SAIDA, Kazuaki TAKASHIMA, Tsuyoshi YAMANE, Yoshihisa YAMANE

2013 Volume 46 Issue 2 Pages 29-35
Published: 2013
Released on J-STAGE: September 12, 2014

DOIhttps://doi.org/10.11276/jsvc.46.29

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Cats diagnosed as aortic thromboembolism were performed with monotherapy using anticoagulant agent or combined therapy using thrombolytic agent, the efficacy of those therapies were discussed. Survival time, hours of forelimb or hind limb paralysis onset, palpable or not of pressure of femoral artery (unilateral or bilateral) on the first day, the days for palpable pressure of femoral artery, and pulmonary edema or not on the first day, were discussed between each therapy group. Fifteen cats were identified as having had a prescription filled for anticoagulant therapy using low molecular weight heparins (low molecular weight heparins group: n=8) or thrombolytic therapy using tissue plasminogen activator (low molecular weight heparins group+tPA group: n=7) between 2002 and 2011. The half survival time of low molecular weight heparins group and low molecular weight heparins group+tPA group were 742 and 5 days, respectively, in low molecular weight heparins group, survival time was longer significantly than that of low molecular weight heparins group+tPA group (p<0.05).

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

2013 Volume 46 Issue 2 Pages 37-42
Published: 2013
Released on J-STAGE: September 12, 2014

DOIhttps://doi.org/10.11276/jsvc.46.37

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[in Japanese]

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A Canine Case of Sick Sinus Syndorome (Rubenstein-II) Successfully Treated with Cilostazol: Findings on Monitoring with Holter Electrocardiography

Migiwa KOMIYA, Noriyuki SASAKI, Tetsuya TANABE, Takahiro OHMORI, Ryuji ...

2013 Volume 46 Issue 2 Pages 43-51
Published: 2013
Released on J-STAGE: September 12, 2014

DOIhttps://doi.org/10.11276/jsvc.46.43

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A 13-years-old female Shiba-breed dog was seen because of syncope and wobbling motion. A monitoring scalar electrocardiography showed high frequency sinus arrests and atropine test was positive. Oral atropine sulfate had been administered for the treatment. Afterwards, the clinical sign had disappeared. On the 378th day, syncope relapsed again and atropine test became negative. Based on the results of electrocardiography and atropine test, Sick Sinus Syndrome was strongly suspected. Administration of cilostazol, which is a phosphodiesterase inhibitor, and enalapril maleate resulted in an immediate disappearance of the clinical signs again. Monitoring holter electrocardiography was conducted before and after the treatment. The cilostazol therapy couldn't increase the total daily heat-beat counts. However, frequency of sinus arrest that exceeds 6 seconds decreased, and the maximal period of sinus arrest was favorably shortened.

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