Advances in Animal Cardiology
Online ISSN : 1883-5260
Print ISSN : 0910-6537
ISSN-L : 0910-6537
Volume 31, Issue 1
Displaying 1-5 of 5 articles from this issue
  • Sachiko Miyagawa-Tomita
    1998 Volume 31 Issue 1 Pages 1-17
    Published: 1998
    Released on J-STAGE: March 05, 2010
    JOURNAL FREE ACCESS
    Normal development of the heart and great arteries requires the contribution of the cardiac neural crest. Ectomesenchymal cells from this area of the neural crest migrate to pharyngeal arches 3, 4, and 6, where they support development of the aortic arch arteries and give rise to connective tissues. The cells continue their migration from the pharyngeal arches to specific sites in the outflow tract of the heart. Removal of the neural crest before migration results in two major types of malformations: truncal septation defects and aortic arch anomalies. Truncal septation is disturbed when the cells do not reach the outflow tract. Patterning of the aortic arch arteries is perturbed when the cells do not form connective tissue and tunica media to support the aortic arch arteries. With the advent of genetically based animal models with cardiovascular anomalies, some of which are neural crest related, it becomes important to understand what we know from ablation studies and which questions remain. Some possible molecular mechanisms involved in specifying the neural crest and/or outflow tract for participation in heart development are discussed.
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  • Takayuki MURAKAMI
    1998 Volume 31 Issue 1 Pages 18-25
    Published: 1998
    Released on J-STAGE: September 17, 2009
    JOURNAL FREE ACCESS
    The congenital cardiovascular anomalies in large and medium sized animals are reviewed. The incidences of cardiovascular anomalies were 0.2 to 4.1% among the animals in the reviewed reports. The most common anomalies were ventricular septal defect (VSD), tricuspid atresia and tetralogy of Fallot in the horse ; VSD, double outlet right ventricle and tetralogy of Fallot in the cattle ; VSD, atrial septal defect, endocardial cushion defect and aortic stenosis in the swine ; VSD and tetralogy of Fallot in the sheep respectively. The agent of cardiovascular anomalies was unknown.
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  • Masayuki KOBAYASHI, Yoko KASHIDA, Noboru MACHIDA, Keiji KIRYU
    1998 Volume 31 Issue 1 Pages 26-33
    Published: 1998
    Released on J-STAGE: September 17, 2009
    JOURNAL FREE ACCESS
    In order to examine the spontaneous occurrence of arrhythmias in 2 groups consisting of 18 racing pigeons and 48 feral pigeons, electrocardiograms using standard bipolar limb leads ( I, II and III) were recorded in both the groups of pigeons at rest. The racing pigeons showed a significantly higher incidence of arrhythmias than the feral pigeons (racing=100% ; feral=50.0% ; p<0.001). The incidence of every one of such arrhythmias in the racing, revealed sinus arrhythmia (SA) in 18 (100%), sinoatrial block or sinus arrest (SAB/SAT) in 11 (61.1%), second-degree atrioventricular block (2°AVB) Mobitz type I (Wenckebach type) in 6 (33.3%), and ventricular premature contraction in 3 (16.7%). The feral revealed SA in 12 (25.0%), SAB/SAT in 12 (25.0%), and 2°AVB Mobitz type I in 1 (2.1%) and Mobitz type II in 4 (8.3%). The present results showing differences of incidence of arrhythmias in the 2 groups of pigeons, suggest that the racing pigeon may be not only a relevant animal for studying arrhythmias related to the athletic heart but may be useful in correspondence with equine cardiology.
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  • Syuichi CHIMURA
    1998 Volume 31 Issue 1 Pages 34-42
    Published: 1998
    Released on J-STAGE: September 17, 2009
    JOURNAL FREE ACCESS
    Pulmonary edema is often encountered as an acute symptom of left insufficiency in mitral regurgitation. Diuretics or vasodilator is generally administered to improve pulmonary congestion. Among the nitroglycerin formations, the rapid acting sublingual tablets were selected in this study. A new administration route of sublingual tablets were devised into preputial cavity in male and into vagina in female, Preclinically this administration was performed in clinically healthy dogs. The cardio-vascular behavior after this preclinical administrations to the dogs were almost same of those after sublingual administration to human. We considered that this administration was clinically applicable. Relatively mild cases of pulmonary edema with clinical symptoms, were initially treated with intra-preputial or intra vaginal administration of nitroglycerin sublingual tablets. Remarkable clinical improvement was recognized in these cases.
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  • 1998 Volume 31 Issue 1 Pages 43-46
    Published: 1998
    Released on J-STAGE: September 17, 2009
    JOURNAL FREE ACCESS
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