巻号一覧
10 巻, 3 号
選択された号の論文の7件中1～7を表示しています
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MASATOSHI OKAMOTO1963 年 10 巻 3 号 p. 159-168
発行日: 1963年
公開日: 2011/01/25
ジャーナル フリー1) The metabolism of endogenous and exogenous urinary cortisol by means of the administration of cortisol-4-14C or cortisone-4-14C was studied in normalsubjects, patients with hyperthyroidism and Cushing's syndrome.
2) The urinary outputs of THE and ATHF in hyperthyroid patients were increased above the level in normal subjects, while the output of THF was similar to normal subjects. The ratios of ATHF/THE and THE/THF+ATHF in hyperthyroidism were increased about 3.0 and 2.0 times more than those in normal subjects. It would appear that in hyperthroidism 5α-reduction of A ring of steroid is predominant over 5β-reduction and that the increased THE is due not only to an increased 11-oxidation (F→E), but to an increased reduction of A ring (E→THE).
3) The urinary output of THF in Cushing's syndrome on the other hand, was increased in comparison with that of THE. The ratio of THE/THF+ATHF was decreased to about 50% of that in normal subjects, while the ratio of ATHF/THF was similar to that of normal subjects.抄録全体を表示PDF形式でダウンロード (810K) -
HARUO KOBAYASHI, JIRO NAGAI, MOTOO NAITO1963 年 10 巻 3 号 p. 169-174
発行日: 1963年
公開日: 2011/01/25
ジャーナル フリーRelationship between the spontaneous lobule-alveolar formation and estrous cycle was observed in mice. Sixty-three virgin mice were devided into two groups: 41 mice were caged four and 22 mice were caged singly. Those mice were observed daily vaginal smear, body weight at every 10 days of age, ovarian and uterine weight at autopsy and presence or absence of lobulealveolar formation in the mammary gland. Results obtained are as follows.
1. Most of the positive SAF mice experienced long estrous cycles before the examination of the mammary gland. But 3 out of 63 mice showed the positive SAF without experiencing long estrous cycles and 6 out of 63 mice with long cycles had not showed the positive SAF.
2. The frequency of long estrous cycles and of the positive SAF was much higher in the grouped mice than in the singly caged mice.
3. The vaginae of the positive SAF mice opened somewhat earlier than those of the negative SAF mice.
4. The weight of body, ovary and uterus at autopsy was somewhat heavier in the positive SAF mice than in the negative SAF mice.抄録全体を表示PDF形式でダウンロード (599K) -
TAKASHI KOBAYASHI, TAKURO KOBAYASHI, JUNZO KATO, HIROSHI MINAGUCHI1963 年 10 巻 3 号 p. 175-182
発行日: 1963年
公開日: 2011/01/25
ジャーナル フリーThe neural mechanism of the hypothalamus in the regulation of the reproductive function in rats was studied from the view point of the choline acetylase activity in the brain. The cyclic fluctuation in the enzyme activity during the estrous cycle and the marked increase in the activity following castration in the hypothalamus were found. The fluctuation of the enzyme activity was somewhat different between the anterior-and the posterior hypothalamus; the former mainly consisted the cyclic fluctuation of the enzyme activity in the whole hypothalamus during the estrous cycle, and the latter caused the elevation following castration. Sex difference in the pattern of the change of the choline acetylase activity in castrated animals was also observed. The fluctuations in the hypothalamic choline acetylase activity observed in this study would suggest an importance of the role of the cholinergic enzyme system in the by pothalamus in the reproductive function.抄録全体を表示PDF形式でダウンロード (780K) -
KEISHI MATSUMOTO, TOKUICHIRO SEKI1963 年 10 巻 3 号 p. 183-189
発行日: 1963年
公開日: 2011/01/25
ジャーナル フリーA new chemical method which separates and measures quantitatively estriol, 16-epiestriol, estradiol-17β and estrone in male and female non-pregnancy urine is described. This method involves acid hydrolysis, extraction with ether-toluene mixture, separation of phenolic fraction from the neutral fraction, purification of the phenolic fraction by refluxing with alkali and alkali washes, chromatographic separation of estriol, 16-epiestriol, estradiol-17β and estrone using partially esterified Amberlite IRC-50 as the adsorbent and a mixture of ethanol and water (3:2 by vol.) as the eluting solvent. The purified fractions are measured by the fluorometric method.
Recoveries of estriol, 16-epiestriol and estradiol-17β(6-4μg) added to normal male urine before acid hydrolysis were, on the average, from 70 to 76% and that of estrone (4μg) was 61%.抄録全体を表示PDF形式でダウンロード (563K) -
P. N. SRIVASTAVA1963 年 10 巻 3 号 p. 190-198
発行日: 1963年
公開日: 2011/01/25
ジャーナル フリーGoldfish, Carassius auratus L., were treated with radioiodine and thiourea. In the former the thyroid follicles were completely destroyed, and in the latter they had become hypertrophied and hyperplastic and were devoid of colloid. The follicular cell height had been greatly increased. When they were kept in aquaria with radiophosphorus, the uptake after either type of treatment was similar and it was half of that of the controls.
The uptake of P32 in the thiourea treated fish increased by 41.9% after acetone-dried goldfish pituitary gland injections, whereas in radioiodine treated fish there was no significant change.
Radioiodine treated fish, when injected with thyroxine, increased their uptake of P32 by 50% but it was even then less than that of the controls. When thiourea treated fish were injected with thyroxine, their P32 uptake was restored to the level of that of the controls.
The conclusion drawn from the present investigations is that in fishes, which lack parathyroid glands, the thyroid gland exercises a great influence over the metabolism of phosphorus and that the pituitary gland has also an indirect control through its thyrotrophic hormone.抄録全体を表示PDF形式でダウンロード (897K) -
TAKASHI KOBAYASHI, TAKURO KOBAYASHI, TOMONORI KIGAWA, MASAHIKO MIZUNO, ...1963 年 10 巻 3 号 p. 199-201
発行日: 1963年
公開日: 2011/01/25
ジャーナル フリーThe rat anterior pituitary was cultivated by means of organ culture technique. The prolactin secretion in this gland was maintained or rather accelerated during 12 days cultivation. This means that the rat anterior pituitary can secrete prolactin under complete deprivation of hypothalamic control. Gonadotropin secretion was declined under the same culture condition.抄録全体を表示PDF形式でダウンロード (236K) -
SHOJI HARA, MICHIKO TAKEUCHI1963 年 10 巻 3 号 p. 202-207
発行日: 1963年
公開日: 2011/01/25
ジャーナル フリーPDF形式でダウンロード (319K)
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