GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
Volume 27, Issue 9
Displaying 1-22 of 22 articles from this issue
  • Masaharu TATSUTA, Hiroyasu IISHI, Shigeru OKUDA, Hiroji KAWAMOTO, Haru ...
    1985 Volume 27 Issue 9 Pages 1707-1715
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    The accuracy of diagnosis by endoscopic biopsy of gastric cancer was investigated. Between 1968 and 1976, a total of 1, 333 healthy subjects and patients with benign and malignent gastric disease was followed-up by endoscopic or epidemiological procedures. Out of 858 patients whose lesions were previously dianosed as benign (Groups I, II and III), a total of 31 patients was diagnosed as having malignant lesions by the follow-up examinations. Grossly, I molar type, depressed lesion with ulceration (III, III-IIc, IIc-III), Borrmann type 4, and sarcoma were frequently misdiagnosed by the endoscopic biopsy at the first examination. In these cases, a correct target biopsy was difficult, because the lesions were associated with marked marginal ridge or stenosis and the extent of cancerous lesions was very small. Close follow-up examinations combined with gastric biopsy were useful for correct diagnosis. We developed gastric aspiration biopsy under direct vision of gastrofiberscope using heparinized fine-needle. This method was useful for diagnosing malignant tumor covered with gastric mucosa. Out of 475 patients whose lesions were diagnosed as malignant (Groups IVor V, and sarcoma), histological examinations of specimens obtained by gastrectomy showed that there was no cancerous lesion in 3 cases. Grossly, these cases were all depressed lesions with active ulceration. The sensitivity of the endoscopic biopsy for gastric malignancy was 93.8% and the specificity was 99.6%. Therefore, this procedure is very reliable method for the diagnosis of gastric malignancy.
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  • -ASSAY PROCEDURE AND CLINICAL APPLICATION-
    Masae KAWAMURA, Mutsuo SHIGEMOTO, Humihiko KURIMOTO, Tatsuji KOMATSU, ...
    1985 Volume 27 Issue 9 Pages 1716-1722
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    We restudied the previous assay procedure of gastric mucosal PGE2, tried a little simplification of its steps, and measured PGE2 of human gastric mucosal biopsy specimen. In the purification step we used high-performance thin layer chromatography (HPTLC) and omitted the degreasing step. In radioimmunoassay we used Pasteur's antibody which was sensitive and specific. In this method the recovery of 3H-PGE2 was 47.7±7.6% (n=29). At-30°C the gastric mucosal tissue was stable for 15 days, and PGE2 levels, with gastric mucosal tissue weights ranging between 5 and 50mg, were well correlated. PGE2 levels of healthy adult male were 3, 130±943ng/gw.w(n=6) in the fundic mucosa and 3, 720 ± 149 (n=6) in the antral mucosa. PGE2 levels of the adult male who had gastric erosion were 1, 315 ± 790 (n=5) in the f undic mucosa and 1, 402 ± 589 (n=6) in the antral mucosa. PGE2 contents of both fundic and antral mucosa were significantly reduced in the erosive stomach (p <0.005). Gastric mucosal PGE2 showed the similar tendency with other defensive factors.
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  • Ching-Ming CHANG, Kazumasa MIKI, Hirohumi NIWA, Shih-Che HUANG, Yoji H ...
    1985 Volume 27 Issue 9 Pages 1723-1730
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    Radioimmunoassay of serum pepsinogen I(PG I) and serum pepsinogen II (PG II) was performed to 209 normal controls, 112 gastric ulcer cases and 142 duodenal ulcer cases of which diagnosis were made endoscopically. One hundred and six cases of peptic ulcer received the gastric analyses and the endoscopic Congo red test on the other day, and then the age differences of those in peptic ulcer cases were analysed. Results were obtained as follows: 1) There were more cases of gastric ulcer located in high position founded in the aged, which showed low levels of serum pepsinogen and low gastric acid-pepsin outputs, but gastric ulcer cases of the aged located in low position showed high levels of serum pepsinogen and high gastric acid-pepsin outputs, those were not different from the other younger ages. 2) Almost all the cases of duodenal ulcer in the aged had a closed-type of glandular border by Congo red test, which showed high levels of serum pepsinogen and high gastric acid-pepsin outputs as well as the other younger ages. In conclusion, there was no special secretion function which was shown in peptic ulcer cases of the aged from the view points of the stage and the location of peptic ulcer.
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  • Katsuhide SHIMAKURA, Takashi SHIRAI, Kotaro YAMAGUCHI, Hidenori NAKAMA ...
    1985 Volume 27 Issue 9 Pages 1731-1740
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    Of 98 patients with malignant biliary obstruction, ERBD was successfully done in 83 cases during the last 19 months (May 1983 to November 1984). Among the 83 patients in whom the implantation of an endoprosthesis was successful, 22 patients underwent operation after ERBD. The remaining 64 cases including 3 cases underwent probe laparotomy have been followed up conservatively. Among them 14 cases have been followed over 6 months, with the longest duration of 464 days. The early and late complications of ERBD occurred in 6 cases (6.1%) and 38 cases (47.8%) respectively. Most frequent late complications were cholangitis and clogging of the endoprosthesis, which occurred in 23 cases (27.7%) and 10 cases (12.0%) respectively. Functional lifetime of the 10 Fr, polyethylene endoprosthesis was 164±83 days (range : 91-394 days) in the firstly implanted endoprosthesis, and 39±19 days (range: 14-70 days) in the endoprosthesis exchanged 2 to 3 times due to clogging Thus, especially in the latter cases, the endoprosthesis should be cleaned periodically by ERC for preventing clogging of the endoprosthesis and prolonging its functional lifetime. And it is necessary to clean the endoprosthesis immediately by ERC when cholangitis develops in the patients over 3 months after ERBD, as cholangitis sometimes leads to the cause of death.
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  • Toshio TANABE, Satoaki MIMA, Teruki HANEW, Hitoshi MIZUO, Hiroshi KANA ...
    1985 Volume 27 Issue 9 Pages 1741-1749
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    Twenty-two cases of alcoholic liver cirrhosis were studied over 60 times by serial laparoscopy and liver biopsies. All cases were male, not HBV carriers and had no history of transfusion. Twenty-one cases continued drinking alcohol. Follow-up periods ranged from 12 to 99 months with an average of 44.5 months (Table 1). Laparoscopic and histological classification of alcoholic liver cirrhosis were as follows : micronodular; size of nodules is less than 3 mm in diameter, macronodular ; size of nodules is larger than 3 mm in diameter, narrow septum ; width of septum is narrower than one third of the liver lobule, broad septum ; width of septum is broader than one third of the liver lobule (Table 2). In general, early stage of alcoholic liver cirrhosis could mostly be classified as micronodularnarrow septum type and nodules were nearly uniform in size. With exacervation of liver diseases, the nodules became hetrogenous in size and the septum tended to be much broader (micro or macronodular-broad septum type). At final stage the nodules became much larger and the septum tended to be narrower (Figure 15). The dye scattering method is very useful in clarifying transition of this change with excellent correlation to fine collagen fibers stainned by Azan blue stainning. Transition of alcoholic liver cirrhosis from micronodular to macronodular type were well observed by laparoscopy. Adequate medical control of Gastrointestinal bleeding of alcoholic liver cirrhosis resulted in improvement of expected survival and inreasing hepatocellular carcinoma transformation.
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  • Yugo NAGAI, Masaharu KATSUMI, Katsuyoshi TABUSE, Yoji TABUSE, Osamu AO ...
    1985 Volume 27 Issue 9 Pages 1750-1756_1
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    The hemostatic effect of endoscopic microwave coagulation method on upper gastrointestinal bleeding was evaluated clinically. Hemostasis over 72hours was achieved in 23 of 25 cases (92%) with upper gastrointestinal bleeding by the endoscopic microwave coagulation method. It is noteworthy that this method was effective in all 7 cases of pulsatile bleeding from exposed vessels and in 13 of 15 cases (87%) in shock state. Surgical operation was carried out in 5cases because of rebleeding. Only one case was operated on within 24hours after microwave coagulation, and the other 4 cases were done 5 to 7 days after. We conclude that this method is useful for emergency endoscopic hemostatis on upper gastrointestinal bleeding, especially pulsatile bleeding from exposed vessels.
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  • Yoshinori IGARASHI, Sumio FUJINUMA, Kunihisa NISHIKAWA, Hironori KOWAZ ...
    1985 Volume 27 Issue 9 Pages 1757-1761_1
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    Relationship between herpes zoster and upper gastrointestinal lesions were studied from Jan. 1982 to Dec. 1984. During this period of the study, 80 cases of herpes zester were admitted to our hospital. In 41 cases of herpes zester, upper gastrointestinal endoscopic examinations were performed with a foward-viewing endoscope (GIF-P3, Olympus, Co., Tokyo). Of these, abnormal endoscopic findings were noted in 38 cases (92.7%) ; 31 gastric lesions, 4 esophageal lesions and 3 duodenal lesions. We evaluated abnormal endoscopic findings in relation to age, the period from the onset of skin rash to endoscopy and the site of skin lesions. In patients under age 50, the incidence of gastric erosions were significantly higher than other lesions. Especially under age 30, gastric erosions were present in the prepyloric area. Within 3 weeks from the onset of skin rash, the incidence was significantly higher. Especially within 2 weeks, gastric erosions were apparent in the prepyloric area. Within 3 weeks, the incidence of gastric ulcer was also higher. In cases with herpes located on the head or the abdomen, many gastric erosions were seen. In cases with herpes on the chest, many gastric ulcers were noted. A case with chest exanthema had a gastric carcinoma at cardia.
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  • Toshio TANABEI, Masanori HIRAO, Hiroji NAKA, Takasi KOBAYASHI, Kimio M ...
    1985 Volume 27 Issue 9 Pages 1762-1771
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    For the purpose of arresting hemorrhage from the upper digestive tract, endoscopic local injection of the HS-E solution has been performed for 38 AGML and ADML cases of serious systemic diasease at our hospital from October 1978 to December 1983. Thirty eight cases of serious systemic disease were as follows ; liver failure, 10; cerebrovascular attack, 6 ; renal failure, 5 ; heart failure, 5 ; post operative bleeding, 5 ; multiple bone fracture, land others, 5 (Table 1). An exposed vessel within the lesion was detected 32/38 cases (84%). Foci of hemorrhage were mostly small lesions, but wide gastric mucosal bleeding were encounterd in several cases.The site of initial bleeding was mainly located in the upper gastric body along thelesser curvature (Figure 5). Through repeated endoscopy the site of bleeding was observedto migrate in 6 cases, though there is of no rule for it (Figure 6). From the standpoint of serious systemic complication and presence of exposed vessel, endoscopic therapy was recommended. Local injection of HS-E therapy was succeeded in arresting acute gastrodoudenal mucosal bleeding in 36/38 (94.7%) (Table 2). Because tissue damage by HS-E solution is minimal, local injection of HS-E solution can be repeated and applied for various types of bleeding including wide spreaded mucosal bleeding.
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  • Rintaro INOUE, Hideo IKEDA, Reiichiro HIDAKA, Kazuhiro OOMAGARI, [in J ...
    1985 Volume 27 Issue 9 Pages 1772-1776_1
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    A 55-year-old man with alcoholic liver cirrhosis was admitted to our hospital because of hematemesis and tarry stool. Emergency endoscopy disclosed bleeding jet from the varix of the lower esophagus and hemostasis was obtained by successful emergency endoscopic injection sclerotherapy (EIS) with intravariceal injection of 5% Ethanolamin Oleate (5% EO). Consequently elective EIS was followed on five times in two months for eradication of varices. During the treatment, serial endoscopic studies revealed a flat elevated superficial tumor on the organised varix at 33cm from the upper incisor. By biopsy examination of the tumor, histological diagnosis of squamous cell carcinoma was made. Surgical operation was performed and the resected specimen revealed a well differenciated squamous cell carcinoma with invasion limited to the muscularis mucosae and without lymph node metastasis. In the resected specimen, intravariceal thrombosis was found in the lower esophagus. The varices obliterated by the organised thrombosis were completely collapsed. On the other part, recanarization within thrombosis was noted but it was considered that esophageal varix would not recur through recanalized vessels in the organised thrombosis.
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  • Mitsuo HAI, Katsuji SAKAI, Yoshiro HAMANAKA, Masayuki HIGASHINO, Harus ...
    1985 Volume 27 Issue 9 Pages 1777-1783
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    A 47-year-old male complaining discomfort at the epigastrium was referred to us with the diagnosis of early esophageal cancer. But a superficially elevated lesion at middle thoracic esophagus by Barium swallow indicated the diagnosis of benign esophageal tumor. Endoscopy revealed an elevated lesion with a granular surface on the posterior of the esophagus 29 cm from the incisor. The histological diagnosis of esophageal papilloma was established by endoscopic biopsy. As the tumor was apprehended to grow into a malignant one and endoscopic resection of the lesion was thought to be impossible because of its sessile conformation, transthoracic resection was performed. The observation of the specimen revealed a superficially elevated lesion and the histological diagnosis of benign esophageal squamous cell papilloma. In this study we have reviewed nine cases of binign esophageal tumor treated at our department over the past 12 years as well as 25 cases of esophageal squamous cell papilloma collected from medical references (including our own case).
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  • Chikao SHIMAMOTO, Kazuo ABE, Kazuhiko IWAKOSHI, Kiyoshi ASHIDA, Shinya ...
    1985 Volume 27 Issue 9 Pages 1785-1790_1
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    A 66 year-old woman came to the O. P. D. of dermatology because of erythematous plaques with itching on the face, extremities and body except back and anterior chest. During the dermatological treatment which were completely ineffective, she complained of loss of appetite and weightloss. Then, the upper GI series was performed in our department, revealing gastric cancer invaded from cardia to antrum. Total gastrectomy was done. One month after gastrectomy, the erythematous lesion had almost disappeared. It has been well known that there is some relationship between internal malignancy and the skin lesion. We conjectured that skin lesion of our case was a kind of skin marker of gastric cancer because of no responce for dermatological treatments, but disapperaredafter gastrectomy. Therfore, further examination must be performed to clarify whether refractory skin lesions were associated with internal malignancy.
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  • Saburoh KAMOI, Yasuhiro SHIMOTSUURA, [in Japanese], Reiichiroh HIDAKA, ...
    1985 Volume 27 Issue 9 Pages 1791-1797
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
    JOURNAL FREE ACCESS
    A 33-year-old female was referred to our hospital for further medical evaluation of epigastric pain and a submucosal tumor of the stomach. Examinations by X-ray and endoscopy in our service also revealed a possible gastric submucosal tumor. Further workup included CT, US, submucosography and laser irradiation. However, a diagnosis of submucosal tumor was not definite because of ulcer displacement initially made at the tumor top by laser irradiation for the purpose of submucosal tissue biopsy. Final diagnosis of hepatic hemangioma of the left hepatic artery was made by angiographic study.Surgical operation disclosed hemangioma originated from the left lobe of the liver compressing the gastric wall. Angiographic study could be mandatory for evaluation of submucosal tumor of the stomach and an useful tool for differential diagnosis.
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  • Kiyoshi IGARASHI, Mitsuroh CHIBA, Tsukasa YOSHIDA, Hiromasa OHTA, Masa ...
    1985 Volume 27 Issue 9 Pages 1798-1806_1
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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    A case of Waldenström's macroglobulinemia with extensive infiltration into the gastrointestinal tract was reported. The patient was sixty-two years old male. His chief complaint was general malaise, hematemesis and rectal bleeding. Serum IgM was markedly high (2376 mb/dl) and monoclonal. λ type was identified by an immunoelectrophoresis. There was sixteen percentage of atypical lymphocytes in peripheral blood. From these, he was diagnosed as Waldenström's macroglobulinemia. Hepatosplenomegaly and a mass in the right lower quadrant were found by a physical examinathon. X-ray and endoscopic examination of the gastrointestinal tract revealed various lesions : the thickening of mucosal folds like giant folds, diffuse erosions and ulcers in the stomach, the scattered erosions in the duodenum, polypoid lesions, erosions and ulcers in the terminal ileum, flat or semipedunculated elevations which looked like submucosal tumor in the segment of the transverse colon. There were marked infiltrations of lymphocytes in the lamina propria mucosae in all of the biopsied specimen from the lesions stated above. Within the area of lymphocytes infiltration, clusters of atypical lymphocytes which were stained with anti-IgM and anti-λ serum by immunoperoxidase technique (PAP) were demonstrated. Thus these lesions were diagnosed as gastrointestinal involvement of Waldenström's macroglobulinemia. Only a limited number of paper on gastrointestinal involvement in Waldenström's macroglobulinemia has been reported. A brief review of the literature is made in this paper.
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  • Shuji OKUYAMA, Tomoaki NAGASHIMA, Kaoru IKE, Yoshimi SHIBATA, Eiji MUT ...
    1985 Volume 27 Issue 9 Pages 1807-1812_1
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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    An 85-year-old male with a high degree of anemia was admitted to our hospital for close examination. After his admission, he repeated melena frequently. However, no abnormal findings were obtained from a radiography of the upper digestive tract and a duodenofiberscopy. The barium anema revealed diverticula in the sigmoid colon. Other than this, no lesions which were considered to be responsible for bleeding could be found. Subsequently, frequent vomiting appeared in addition to mlena. Therefore, an abdominal angiography was performed. In the area dominated by SMA jejunum, a round heavily stained image of the tumor was observed. At the site corresponding to this, a roentgenography of the small intestine demonstrated a 2.5×3.5 cm sized submucosal tumor associated with ulceration. Endoscopy of the small intestine also revealed submucosal tumor with surface ulceration. From these findings, a tumor of the smooth muscle was suspected strongly. Abdominal CT scan showed invagination caused by th tumor. The patient was operated on Pathohistologically, the diagnosis of leiomyoma with a primary lesion in the jejunum was established.
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  • Seiji SHIMIZU, Masahiro TADA, Keisuke KIYOTA, Masao KOBAYASHI, Sotaro ...
    1985 Volume 27 Issue 9 Pages 1813-1821
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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    Newly developed WAVE system (Welch-Allyn VideoEndoscope system) comprises videoendoscope, video processor, television monitor, character generator keyboard, and video tape recorder. The image sensed by the CCD chip attached to the distal tip of the scope is electronically transmitted to video processer for display by television monitor. Examination is performed by referrence to the television monitor, and many persons can follow the examination at the same time. The image provided by this system may be superior to the conventional one in resolution of the detail and color. Application of a computor at the level of image processing is expected to open a new field in endoscopic diagnosis. Documentation of the entire examination by video tape recorder enabled to render dynamic and reliable data for diagnosis. Still photographs can also be obtained from the television monitor. There is still some problems with mechanical characteristics, however, this system is considered to herald the innovation in the art of endoscopy.
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  • Tatsuya ITOSHIMA, Minoru UKIDA, Toshio ITO, Shuzo HATTORI, Masahiro KI ...
    1985 Volume 27 Issue 9 Pages 1822-1831
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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    Peritoneoscopy was performed in 3, 212 cases (male 2, 481, 77.2% ; female 731, 22.8%) in the 26 years period from 1958 to 1983. 98% of the cases were liver diseases and liver biopsy was performed under the guide of peritoneoscope. 83% of them were classified by Shimada's classification : code number 200 (43%), 300 (16%), 400 or 500 (liver cirrhosis, 18%) and 100 (9%). Repeated peritoneoscopies of 249 patients (543 times) demonstrated that the code number system indicates well the activity and prognosis of chronic hepatitis. Complications of peritoneoscopy or liver biopsy were observed in 21 cases (0.65%) ; abdominal bleeding in 10 cases (0.31%). One case (0.031%) died after liver biopsy using a Robbers f oreceps. Forty-nine reports with more than 500 peritoneoscopies were collected. Peritoneoscopy in association with liver biopsy has contributed to diagnosis of liver diseases and will continue to develope as a direct observation method which accomplish non-bloody imaging methods.
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  • [in Japanese]
    1985 Volume 27 Issue 9 Pages 1832-1843
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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  • [in Japanese]
    1985 Volume 27 Issue 9 Pages 1843-1851
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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  • [in Japanese]
    1985 Volume 27 Issue 9 Pages 1851-1854
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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  • [in Japanese]
    1985 Volume 27 Issue 9 Pages 1854-1874
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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  • [in Japanese]
    1985 Volume 27 Issue 9 Pages 1875-1879
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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  • [in Japanese]
    1985 Volume 27 Issue 9 Pages 1879-1896
    Published: September 20, 1985
    Released on J-STAGE: May 09, 2011
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