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Volume 44, Issue 6
Displaying 1-10 of 10 articles from this issue
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Takashi SHIMOYAMA, Yoshihiro FUKUDA, Kazutami TAMURA2002 Volume 44 Issue 6 Pages 957-979
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSTwenty-one years have elapsed since Dr. Barry Marshall succeeded in culturing Helicobacter pylori for the first time in the world, and 20 years have elapsed since Dr. Hiroyuki Inoue, who was a post-graduated student in our department, cultured it for the first time in Japan. For this reason, 2001 was a special year for our H. pylori research. I was privileged with the honor of holding the 61st annual meeting of Japan Gastroenterological Endoscopy Society in Kobe, the first annual meeting in the 21st century, in this special year, and spoke of these 20 years of our H. pylori research in the president lecture. I am deeply grateful to Prof. Hirofumi Niwa, who is the president of Japan Gastroenterological Endoscopy Society and Prof. Shigeru Okuda, who is a man of experience in this field and who presided my lecture, for their kindness. Prof. Takashi Nakamura, an executive editor of this journal has recommended we write a review of our research. We will describe our work (and other results) for the 20 years, mainly focused on animal models and analysis of gene and LPS (Lipid A) in H. pylori. The contents of this paper are : 1. The history of our research 2. The bacterial characteristics of H. pylori 3. The infectious experiment using monkey 4. Bacterial factors including toxin and host factors including cytokines 5. The infectious route focused on childhood infection 6. The outcome (occurrence, relapse) of peptic ulcer associated with H. pylori 7. Mongolian gerbil model 8. Problems of eradication therapy. We do not mention gastric carcinogenesis and MALT lymphoma, because we do not have an established theory yet.View full abstractDownload PDF (26647K) -
Toshifumi OZAWA, Hideki WATANABE, Yuko HORIE, Koji OKUMURA, Toyoichi T ...2002 Volume 44 Issue 6 Pages 980-989
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSBackground & Aim : Inflammatory esophagogastric polyp tended to misdiagnose as a malignant lesion. The aim of this examination was to investigate the correlation of the endoscopic findings with pathologic findings of the inflammatory esophagogastric polyp. Methods : Fourteen patients was histologically diagnosed as an inflammatory polyp in seven years. We investigated endoscopic form, color, iodine staining appearance, location, symptom, grading of GERD, gastric folds, histological findings, therapy and so on. Results : All lesions are divided into two group histologically. Foveolar epithelial type (F type) frequently formed l or ll type protrusion in Yamada's classification endoscopically. F type of these polyps often shows reddish and negative for iodine staining, on the other hand, it accompanies with gastric folds. Squamous epithelial type (S type) often shows type lll of Yamada's classification endoscopically. S type of these polyps often shows mixed color pattern (reddish and discolored), and it's iodine staining shows mixed pattern, (intermingled deep and non-stained area) which is similar to soccer ball. S type, and also is occasionally difficult to differentiate between reactive atypic and malignant change histologically. Conclusions : We should treat these polyps using PPI initially because it is supposed that inflammatory esophagogastric polyps have origineted in GERD. On the other hand, we recom-mend endoscopic resection more actively to make diagnose definitely in a difficult case by only using biopsied specimen.View full abstractDownload PDF (16066K) -
Hirofumi KAWAKUBO, Soji OZAWA, Yutaro KATO, Yoshikazu UEMATU2002 Volume 44 Issue 6 Pages 990-995
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSA 51-year-old man was admitted to our hospital complaining of fever and chest pain. Laboratory tests showed leukocytosis and an elevated CRP level. After a complete clinical examination, the patient was diagnosed to have esophagogastric phlegmon and treated with medication. The patient was discharged from the hospital on the 30th hospital day. Eso-phagogastric phlegmon is a rare inflammatory disease that is very difficult to diagnose definitively. Since this disease is often fatal, early diagnosis and treatment are essential. We report a patient with esophagogastric phlegmon who was successfully treated by medication.View full abstractDownload PDF (11616K) -
Kinro SASAKI, Kazuhito MIYACHI, Hidekazu AOKI, Shinichi ONODERA, Taizo ...2002 Volume 44 Issue 6 Pages 996-1000
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSIn the majority of the patients with gastric anisakiasis, edema, redness and/or erosion of the gastric mucosa are observed endoscopically. It is rare that the anisakiasis forms the submucosal tumor, and there are few reports about the endosonographic findings of the granuloma. In order to clarify the components of the tumorous lesion in anisakis granuloma, we evaluated the endoscopic ultrasonography (EUS) findings in two patients with anisakis granuloma. EUS detected the eosinophilic granuloma as a hypoechoic lesion in the third layer of gastric wall, and the central hyperechoic part corresponded to the mite body of anisakis.View full abstractDownload PDF (8338K) -
Ichiro OHSAWA, Toshio YAMAMOTO, Kikuhiro NAKAMURA, Tadataka HAYASHI, T ...2002 Volume 44 Issue 6 Pages 1001-1007
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSA pedunculated mass arising from the second portion of the duodenum was detected in a 66-year-old woman during a follow-up endoscopic examination after treatment of a gastric and duodenal ulcer. The mass was a soft, 3cm-sized, polypoid projection into the lumen and was overlaid by intact duodenal mucosa. When biopsied, clear fluid was exuded from the polyp. Endoscopic resection was performed with a preoperative diagnosis of cystic polyp of the duodenum. The resected specimen revealed a simple submucosal cyst containing clear mucinous fluid, and Brunner's gland hyperplasia was observed in the stalk of the polyp. The wall of the cyst was lined with a single layer of columnar cells, and it appeared to represent cystic change of Brunner's gland hyperplasia. In addition to our own case, 61 cases of Brunner's gland tumor have been reported in Japan in the last decade. We review them from the standpoint of cystic change, and have classified them into four histological categories.View full abstractDownload PDF (12186K) -
Sakae NAGAOKA, Saburo SYUKUWA, Hisayuki HAMADA, Eiji MANABE, Tsuyoshi ...2002 Volume 44 Issue 6 Pages 1008-1014
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSA 79-years-old female visited her home doctor because of a positive fecal occult blood test. Colonoscopy revealed Isp polyp in the rectum, and had EMR (endoscopic mucosal resection) for the lesion. After one year, follow-up colonoscopy was performed, the recurrence was suspected and she admitted to our hospital. Colonoscopy revealed rectal polipoid lesion of which appearance was Isp and 12mm, multiple LST in the cecum and ascending colon. Initial EMR was performed for rectal polipoid lesion, pathological diagnosis of the lesion was adenocar-cinoma in adenoma. The possibility of another lesion with carcinoma can not be ruled out, and lower anterior resection, right hemicolectomy were performed for these lesion. The residual tumor was not noticed in the rectum, and seven LSTs of which size were distributed from 10 to 26mm were found in the cecum and ascending colon. Six LSTs were tubular adenoma, one LST was tubular adenoma with severe dysplasia of the ascending colon. We reported because multiple LSTs are rare.View full abstractDownload PDF (10428K) -
Hiroki IMAZU, Masahiro OCHIAI, Mitsutaka SYOUJI, Yoichi SAKURAI, Toshi ...2002 Volume 44 Issue 6 Pages 1015-1018
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSA 74-year-old male developed tarry stool and anemia while he was staying in a near-by hospital for spastic acroparalysis after brain trauma. Endoscopic examination revealed multiple mucosal vascular ectasias with oozing blood spreading from the cecum to the ascend-ing colon. Conservative treatments failed to cease bleeding so that the endoscopic coagulation of the lesions was conducted. Endoscopic hemostasis was quite successful and endoscopic observation two months afterwards revealed that the lesions of vascular ectasias themselves almost disappeared.View full abstractDownload PDF (5819K) -
Osamu KAWAMURA, Takeshi SAWADA, Takeshi HARA, Tatsuki KODAMA, Haruto S ...2002 Volume 44 Issue 6 Pages 1019-1022
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSA 45-year-old man was admitted to our hospital because of melena. He had intrarectally self-administered 100m1 of Shochu (a kind of Japanese liquor, 35% ethanol) followed by about 200m1 of water as his sexual practice. This enema was performed twice ; i. e. once a day over a two-day period. After the administration of the enema on the 2nd day, he began having melena. An emergent colonoscopy revealed redness, edema, and diffuse erosion or ulcer with marked friability and hemorrages. These changes were confined to 15cm from the anal verge. Histological findings showed complete sloughing off of the surface epithelium, destruction of the glands and blood vessels, and interstitial edema with non-specific neutrophilic infiltration. These microscopic appearances resembled ischemic colitis, but these injuries were more intense in the superficial layar of the mucosa. He was treated conservatively without antiinf lammatory drugs such as corticosteroids, mesalamine and other medications. Anal bleeding disappeared entirely on the 7th hospital day. He refused to have a follow-up colonoscopy, but he has had no recurrence of melena up to the present day.View full abstractDownload PDF (5858K) -
[in Japanese]2002 Volume 44 Issue 6 Pages 1023
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSDownload PDF (195K) -
[in Japanese]2002 Volume 44 Issue 6 Pages 1027-1029
Published: June 20, 2002
Released on J-STAGE: May 09, 2011
JOURNAL FREE ACCESSDownload PDF (417K)
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