One hundred adults with age distribution between 17 and 88 years old who had no history or physical findings of any neuromuscular disease were selected and divided into four groups having 25 cases each. Terminal latency, amplitude, maximal motor nerve conduction velocity (MCV) of M-wave and the shortest latency, latency-variability, duration of F-wave recorded from abductor hallucis muscle by supramaximal percutaneous stimulation of the tibial nerve and the relationship of M-wave and F-wave to age was evaluated.
In the cases more than 50 years old, the shortest F-wave latency (msec/meter) and MCV were closely correlated with increase of age. F-wave duration was calculated as a ratio of F-wave duration to M-wave duration. The correlation between F/M duration ratio and ages showed significant difference statistically, correlation coefficient being 0.8004 (p<0.001) and linear regression equation was Y=0.09X+22.74 (X: years of age, Y: F/M duration ratio). The mean decrease ratio between cases over 70 years old and under 30 years old was 40.0% in F/M duration ratio, 15.3% in the shortest F-wave latency and 10.3% in MCV.

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We studied the influence of visuospatial agnosia on the functional recovery and the improvement of activities of daily living (ADL) in apoplexic hemiplegia.
Among the 36 patients here studied, there were 10 patients with visuospatial agnosia and 26 patients without visuospatial agnosia. All subjects could not walk at the time of admission. The intervals between apoplexic attack and admission were from 15 days to 15 months. It was confirmed by CT scan that the lesions of all patients existed at one side of the supratentorial hemisphere. We used 6 kinds of behavior as the score for ADL, i. e. intake of diet, excretion including transfer from bed to portable toilet, walking, bathing, dressing and mobility in the hospital, and evaluated the level of their behavior as follows-0; unable, 1; partial independence, and 2; independence. Motor recovery in hemiplegia was estimated with the 12-Grade-Test of Ueda et al.
ADL score of all patients with visuospatial agnosia were less than 8 marks after 3 months training. By contrast, all of the control patients were over 10 marks. Motor recovery in lower limb were also less improved in patients with visuospatial agnosia than in control patients.
These results show that visuospatial agnosia is the inhibiting factor of functional recovery and improvement of ADL in apoplexic hemiplegia.

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SLTA (Standard language test of aphasia), a battery of tests for language impairment, has been widely used in Japan since 1974. In order to compare the classification of aphasia by the classical method with that calculated by SLTA profile, 341 poststroke patients with aphasia who had been admitted to Nanasawa Hospital, Kanagawa Rehabilitation Center, from 1975 to 1981 were studied. The SLTA profile of these patients were analysed by means of factor analysis.
“Word fluency” was characteristically disturbed in the patients with amnesic aphasia. “Repetition” were decreased in conduction aphasia, whereas in transcortical aphasia only “repetition” remained intact. On the other hand, discrimination of Broca's aphasia from Wernicke's aphasia was not possible on the SLTA profile, even with the discriminant analysis or cluster analysis.
Factor analysis was executed with the correlation matrix of the 28 items of SLTA, and seven factors were extracted: (1) oral expression and phonological processing; (2) writing; (3) word recognition; (4) comprehension of complex sentences; (5) calculation; (6) writing of Kanjiwords; (7) word fluency.

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Cardiorespiratory responses to treadmill exercise testing in 69 patients (average age 53 years) with coronary artery disease were studied before treatment and average of 23.9 months after the first study. Coronary angiography was performed in all of them before treatment, and 68 of 69 patients were found to have 75% or greater stenosis of one or more major coronary arteries. Thirty five patients (Medical group) were treated medically and 34 patients (Surgical group) were treated surgically (A-C bypass operation), including 24 and 15 patients with myocardial infarction respectively. The relationships between cardiorespiratory changes on exercise on one hand and clinical status and angiographical finding on the other were studied and compared between two groups.
In the first testing, there were no significant differences in mean values of oxygen consumption, Mets, oxygen pulse, heart rate, systolic blood pressure and rate-pressure-product between medical and surgical group. At the second testing using the same work load as the first testing, incidence of ST segment depression and angina was reduced from 24% in the first testing to 12% in medical group and from 46% to 4% in surgical group. Mean values of oxygen consumption, Mets and rate-pressure-product were also significantly decreased in both groups. Comparing the data of the two groups, there was significantly higher heart rate in surgical group than in medical group. At the time of the second testing, many of them already returned to their works.
At the even higher work load in the second testing, 7 medically treated patients with severe coronary artery disease were unable to complete the test because of ST segment depression and angina, on the other hand 33 surgically treated patients except one performed the test without angina even though some of them had had severe coronary artery disease before operation.
These results suggested that both medical and surgical treatment improved clinical findings and exercise performance, but surgical treatment was able to improve exercise performance more remarkably than medical treatment.

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[in Japanese]

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[in Japanese]

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