This is the first report on the combination of sonochemi-stry (the use of power ultrasound to stimulate chemical processes in liquids) with ferrite plating (a wet chemical method for synthesizing spinel ferrite films at low temper-ature from aqueous solution). By means of ultrasonic enhancement, an we successfully encapsulated polyacrylate microspheres whose average diameter was ∼0.25μm with continuous ferrite coating in an aqueous solution of FeC1
2 at 70°C. This broke the previous lower limit (∼0.3μm) on the size of the particles to be encapsulated;without application of the ultrasound waves, the ferrite coating became discontinuous or insular. The magnetic property of the continuous ferrite coating was better than those of the insular coating. The ferrite-encapsulated particles will greatly improve the performance of the enzyme immunoassay, which has been put to clinical use as a cancer test reagent with insular-ferrite-coated particles.
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