Advances in Animal Cardiology

Pharmacokinetics of Digitalis in Some Domestic Animals

Yoshimichi MIYAZAWA, Tomohide SATO, Hideo MIYASHITA

1988 Volume 21 Issue 21 Pages 1-19
Published: 1988
Released on J-STAGE: March 05, 2010

DOIhttps://doi.org/10.11276/jsvc1984.21.1

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Slow Channel Inhibitor Verapamil in the Treatment of Arrhythmia

Akira SHIGA

1988 Volume 21 Issue 21 Pages 20-26
Published: 1988
Released on J-STAGE: September 17, 2009

DOIhttps://doi.org/10.11276/jsvc1984.21.20

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[in Japanese]

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The Epicarpial Activation Map of the Isolated Rat Heart

Tomoe NAKATA, Sadayuki SATO, Souichiro SEKIYA, Takeshi TSUTSUMI, Hiroh ...

1988 Volume 21 Issue 21 Pages 27-35
Published: 1988
Released on J-STAGE: September 17, 2009

DOIhttps://doi.org/10.11276/jsvc1984.21.27

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In order to describe activation sequences on the left ventricular epicaraium(LVEp) of the isolated rat heart, epicardial isochronal maps were obtained by using. Wistar rats Five males, 25-30 weeks of age, which were coofirmed to have noo conduction disturbances by analyting electrocardiograms and vectorcardiograms recorded prior to removing their hearts, were used. Each isolated heart was perfused by the Laogendorff method and was mounted on the cardiac muscle chamber filled with 35 ml normal oxygenated Tyrode's solution at 37°C. It was stimulated by a bipolar electrode with rectangular pulse wave of 4 msec and 2 Hz, the electrode having been placed in the right atrial septum after the sinus node had been crushed. In mappig procedure, a fixed reference bipolar electrode was applied on the surface of LVEp, and a roviog electrode was run by the conventional microelectrode method. The results and conclusion are as follows : 1) The earliest breakthrough site on the LVEp was found in the anterior paraseptal region near the cardiac base. 2) The latest activation site was found at the center of the free wall of LVEp, i. e., The posterobasal region.

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The Influences of Recording Postures on Eletrocadiogram Measurments in Dogs

Yoshikata NAKADA, Jun SUZUKI, Keiji SAMURA, Toshimi USUI

1988 Volume 21 Issue 21 Pages 36-41
Published: 1988
Released on J-STAGE: September 17, 2009

DOIhttps://doi.org/10.11276/jsvc1984.21.36

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In order to elucidate the influences of recording postures on electrocardiogram measurements, limb lead ECGs were recorded using a canine autoanalyzing electrocardiograph for 34 beagle dogs (18 females and 16 males, age; 13-16 months, body weight ; 6.4-11.5 kg). Supine, hanging and right lateral recumbent positions were adopted as ECG recording postures in this study.
The mean QRS axis value by the hanging position was significantly smaller, and its standard deviation was larger than those by the supine and the right lateral recumbent positions, respectively. The mean QRS axis values were 62±19°, 78±9°, and 75±8°by the hanging, the right lateral recumbent and the supine positions, respectively. Furthermore, the mean QRS axis by the hanging position in serial tracing for 5 dogswas not stable as compared with those by the other two positions.
There were no significant differences among these three positions, regarding the heart rate, PR interval, QRS duration, QT interval, P wave and R wave amplitude in lead II. The polarity of T wave was not uniform in any position, and was readily altered by changing the posture.

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Evolution of the Electrocardiogram in Young Dogs during the First 180 days of Life and a Diffenence between Male and Female

Hiroyuki ISHIGURO, Kazuhiko SENNO, Mitsuru INOUE, Terumi SUKEGAWA, Hit ...

1988 Volume 21 Issue 21 Pages 42-47
Published: 1988
Released on J-STAGE: September 17, 2009

DOIhttps://doi.org/10.11276/jsvc1984.21.42

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Electrocardiographical changes during the first 180 days of life were compared between 46 male and 56 female beagle puppies born to the mothers having no history of heart diseases.
Electrocardiograms were recorded by the standard limb leads (I, II, III) and the augmented unipolar limb leads (aVR, aVL, aVF).
1. Electrocardiogrphic examination revealed almost no difference in both sexes.
2. The heart rate registered the maximum on the 10th day of life, and then decreased until the 180th day.
3. The variation of P wave voltage decreased to the 65th day, and then increased until the 180th day. But, the variation of T wave voltage increasied to the 37th day, and then decreased until the 180th day.
4. The variation of R wave voltage increased until the 180th day. But, the variation of S wave voltage decreased until the 180th day.
5. P wave and QRS wave durations prolonged slightly until the 180th day.
6. P-R wave duration shortened during the period of the 30th day to the 40th day of life, and then prolooged until the 180th day. Q-T wave duration shortened until the 41st day and then prolonged until the 180th day.
7. There were 3 types of changes in QRS electrical axis from day 0 of life tgrough to the 180th day, i. e., anticlockwise (male 74%, female 70%), clockwise (male 22%, female 28%) and motionless (male 4%, female 2%).

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Cardiac Pathology for Small Animal Clinician Morphological Examinations of the Heart and Great Vessels

Takao KANAI, Kazuo KOGURE

1988 Volume 21 Issue 21 Pages 48-58
Published: 1988
Released on J-STAGE: March 05, 2010

DOIhttps://doi.org/10.11276/jsvc1984.21.48

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[title in Japanese]

1988 Volume 21 Issue 21 Pages 59-62
Published: 1988
Released on J-STAGE: September 17, 2009

DOIhttps://doi.org/10.11276/jsvc1984.21.59

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