Objective: Unlike distal deep vein thrombosis (DVT), proximal DVT has a high risk of causing pulmonary embolism (PE). The purpose of this study was to investigate the risk factors of proximal DVT after total knee arthroplasty (TKA) in Japanese patients.
Methods: The study included 460 knees in 376 patients who underwent primary TKA (FINE® Total Knee System) between March 2011 and May 2017 at our hospital. Patients included 70 men and 306 women, with a mean age of 72.6 years. To evaluate the presence or absence of DVT, all patients received Doppler ultrasonography (US) preoperatively and on postoperative days (PODs) 2 and 14. Patients with preexisting DVT were detected preoperatively and were excluded from the study.
We investigated the following as risk factors: age, gender, rheumatoid arthritis, range of motion, hypertension, diabetes mellitus, hyperlipidemia, history of venous thromboembolism, hormonal therapy, malignancy, bilateral TKA, operative time, postoperative anticoagulant therapy, and plasma D-dimer values on PODs 3, 7, and 14. We compared these risk factors between the proximal DVT-positive and DVT-negative groups.
Results: DVT was detected in 127 knees (27.6%), including 11 knees with proximal DVT (2.4%). A univariate analysis demonstrated that there was a significant difference in age between the proximal DVT-positive and DVT-negative groups. However, no significant differences were found between the two groups by a multivariate logistic regression analysis.
Conclusion: To our knowledge, this is the first study to investigate the risk factors of proximal DVT after TKA. However, we could not identify independent risk factors from this study.
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