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Volume 7 (1966)
- Issue 6 Pages 513-
- Issue 5 Pages 415-
- Issue 4 Pages 305-
- Issue 3 Pages 201-
- Issue 2 Pages 101-
- Issue 1 Pages 1-
Volume 7, Issue 2
Displaying 1-10 of 10 articles from this issue
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Myron PRINZMETAL1966 Volume 7 Issue 2 Pages 101-102
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSDownload PDF (82K) -
Clarence M. AGRESS, Stanley WEGNER1966 Volume 7 Issue 2 Pages 103-109
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSA comparison of the cardiovascular performance measurements in current use was investigated. Anesthetized animals were studied at rest, and after alteration of hemodynamics by administration of isoproterenol. The best correlations were obtained between the flow-related parameters: stroke work, stroke power, stroke volume, cardiac output and mean ejection rate, in that order. The tension time index, ventricular pressure derivative, heart rate and mean systolic pressure showed no consistent correlations either with the stroke index or between each other. It is concluded that the effects of altered hemodynamics must be considered before using different cardiac performance measurements interchangeably.View full abstractDownload PDF (316K) -
Yoshio WATANABE, Leonard S. DREIFUS1966 Volume 7 Issue 2 Pages 110-120
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSTransition from a regular supraventricular or ventricular mechanism to fibrillation was recorded utilizing 2 ultramicroelectrodes.
Fibrillation in the hypothermic dog heart was preceded by asynchronous repolarization of individual fibers. An early premature beat caused incomplete depolarization of some fibers (local block) and irregular spread of excitation, rapidly disorganizing the ventricles. A similar sequence of events was demonstrated in the development of ventricular fibrillation due to desacetyl lanatoside C. Focal injection of aconitine engendered a sustained, regular ventricular tachycardia characterized by a decreased rate of depolarization and electrical alternation in some fibers. A gradual transition to fibrillation occurred when the timing and configuration of individual action potentials became irregular.
Common factors observed at the onset of ventricular fibrillation were the development of local block and an irregular spread of excitation, demonstrating electrophysiologic inhomogeneity of the ventricles.
During spontaneous ventricular fibrillation in isolated puppy hearts, the Purkinje-ventricular muscle junction was shown to be a possible site of conduction failure in the genesis of local block and irregular spread of excitation.View full abstractDownload PDF (673K) -
Saburo MASHIMA, Longtai Fu, Kokichi FUKUSHIMA1966 Volume 7 Issue 2 Pages 121-129
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe angular range means the range of the direction, in which instantaneous vectors exist. The magnitude of the polar vector is one half of the integral of this angle weighed by square of the instantaneous vector, if the loop is on one plane. It was suggested that the angular range could be used for quantitative estimation of the inscription of the vector loop. The angular range of major vectors was evaluated by means of half maximal vectors. It was pointed out that the obtained value of the angular range might also be used for estimation of the loop area. Frank lead vectorcardiograms of 50 normal subjects and 76 patients with ventricular hypertrophy were examined with the above method in 3 planar projections. The half maximal vector itself was also examined with the QRS loop and found to be of some clinical values.View full abstractDownload PDF (387K) -
Takenori KIKUCHI, Seiyo ENDO, Toshiaki KISHII, Yoshiyasu HASEGAWA, Yos ...1966 Volume 7 Issue 2 Pages 130-135
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSMyocardial individual FFA metabolism was studied in valvular disease and coronary sclerosis using gas chromatography.
In coronary sclerosis, the composition of palmitic and stearic acid in coronary arterial and venous blood was higher, and palmitoleic, oleic and linoleic acid was lower than that in valvular disease.
Concerning the myocardial metabolism of individual FFA, the significantly higher extraction ratio of palmitic acid was found in valvular disease as compared with coronary sclerosis.View full abstractDownload PDF (313K) -
Kunio YAMAKAWA, Kazuo KITAMURA, Tatsuko SUGANO, Masahide UESUGI, Kohko ...1966 Volume 7 Issue 2 Pages 136-153
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSMicroscopic studies of the pulmonary trunk in pulmonary hypertension of 28 cases and control groups of 65 cases ranging from the age of 1 to 83 years were carried out.
The elastic configuration of the media of the pulmonary trunk was classified into 5 types and relationship between the severity of the pulmonary hypertension and changes of the elastic fibers in the media was carefully studied.
As a result, increase of the elastic fibers even in the acquired severe pulmonary hypertension was observed.
This finding is compatible to the views of Meyer although the methods of observation differ and is contradictory to the conclusions of Heath and Saldaiia.
Marked changes of the elastic fibers in the media of pulmonary trunk was not found in dogs injected with lycopodeum spores, which may be due to the short duration of pressure loading.
A close relationship of the elastic fibers with the smooth muscle cells was observed in the electron microscopic studies of animal experiments.View full abstractDownload PDF (6104K) -
Tsuguya SAKAMOTO, Zen'ichiro UOZUMI, Goro KAITO, Hideo UEDA1966 Volume 7 Issue 2 Pages 154-167
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSBased on the comparative study on a large number of phonocardiogram, the recording method which supplies the most valuable information was investigated. One thousand cases were submitted to the simultaneous phonocardiography from various areas using 2 to 4 phonocardiographs. The best method secured in 850 cases is the simultaneous low and high frequency phonocardiograms synchronously taken from 2 to 4 auscultatory areas. By the limitation of a paper width (150mm.), combination of 2 recording sites was preferable. By this recording method, better time resolution of various heart sounds is achieved and the time course of the heart murmurs as well as the relationship between heart sounds and murmurs are completely established, thus the diagnostic accuracy of the phonocardiography improves considerably. The necessity and the value of this method are illustrated by several cases.View full abstractDownload PDF (4731K) -
Jugoro TAKEUCHI, Tetsundo KITAGAWA, Tadashi KUBO, Ichiro MURAI, Tsuneo ...1966 Volume 7 Issue 2 Pages 168-180
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESS(1) The pressure-flow relations in both the hepatic artery and the portal vein system were investigated in a total of 13 dog livers, perfused with the homologous blood by a pump oxygenator. In addition, the interaction between the hepatic artery and the portal vein system was also studied. Thepressures and flows in both the vascular systems were simultaneously measured by means of electromagnetic flowmeters and electric manometers.
(2) HAP was successively raised by stepwise fashion from 30 to 260mm.Hg, while PVP was adjusted at about 10mm.Hg. HAF was increased proportionately less than the rise in HAP within a range of approximately 80-160mm.Hg of HAP, indicating that HAR was raised as HAP was increased. Thus, the presence of autoregulation was demonstrated in the hepatic artery system.
(3) The changes in PVF during the alterations of PVP over a range of 5-40mm.Hg were examined, maintaining HAP constant at about 100mm.Hg. PVF was increased proportionately or more than the rise in PVP, indicating that PVR was unchanged or decreased as PVP was increased. Consequently, it was demonstrated that the portal vein did not autoregulate its blood flow.
(4) PVR was slightly affected by the variation of HAP. On the other hand, HAR was hardly affected by the variation of PVP within a range of 5-30mm.Hg of PVP.View full abstractDownload PDF (1362K) -
Toshio MITSUI1966 Volume 7 Issue 2 Pages 181-187
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSDownload PDF (957K) -
Nobuyasu YAMAZAKI, Koji YAWATA, Hiroshi HANNYA, Eiichi KIMURA1966 Volume 7 Issue 2 Pages 188-195
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSA case of relapsing polychondritis complicated with aortic insufficiency is described in detail.
Clinical characteristics of this disease are systemic inflammatory involvement of cartilages, often complicated with conjunctivitis, scleritis, iritis, otitis interna and otitis media. Acute exacerbation and spontaneous remission of systemic chondritis are characteristic.
The etiology is still obscure, but according to Pearson, an unusual hypersensitive direct reaction to cartilage, sclera and membranes of the middle and internal ear, and some specific acquired deficiency of metabolism or harmful enzyme may be the important factors. Speculation on etiological relation between relapsing polychondritis and aortic insufficiency has been made.
Corticosteroid therapy has been effective to control the acute exacerbation.View full abstractDownload PDF (1985K)
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