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Volume 9 (1968)
- Issue 6 Pages 517-
- Issue 5 Pages 431-
- Issue 4 Pages 321-
- Issue 3 Pages 225-
- Issue 2 Pages 105-
- Issue 1 Pages 1-
Volume 9, Issue 4
Displaying 1-10 of 10 articles from this issue
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Vincenzo LAPICCIRELLA1968 Volume 9 Issue 4 Pages 321-331
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSDownload PDF (702K) -
Vesselin I. ORESHKOV1968 Volume 9 Issue 4 Pages 332-338
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESS(1) By the use of polygraphic tracing including apex cardiogram, phonocardiogram and indirect carotid tracing, an almost full and precise phasic analysis of the cardiac cycle may be obtained.
(2) New methods for the measurement of the ejection period and mechanical systole are presented.View full abstractDownload PDF (1299K) -
Clarence M. AGRESS, Stanley WEGNER1968 Volume 9 Issue 4 Pages 339-348
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSExamination was made of the relationship of left ventricular isovolumetric contraction and ejection times to stroke volume. These studies were performed in humans at cardiac catheterization using the dye dilution technique and in open-chest dogs with electromagnetic flowmeters. The cardiac phases were measured from intracardiac catheters in humans and were calculated from the flow curves in dogs. While the isovolumetric and ejection periods independently gave correlations of only marginal significance with stroke volume, the ratio of these intervals was highly significant: r=0.92 for humans and r=0.86 for dogs.View full abstractDownload PDF (446K) -
Hideo UEDA, Shuichi HATANO, Tadashi KOIDE, Tatsujiro GONDAIRA1968 Volume 9 Issue 4 Pages 349-358
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESS1) External recording of cerebral clearance was performed after Kr85 saline solution injection into the common carotid artery. Clearance curve thus obtained was divided into 3 exponentials. The 3rd phase represents mainly clearance of the area perfused with external carotid artery and the rest of the curve after subtraction of the 3rd phase can be treated in the similar way to that of reported by Lassen et al.
2) The method was applied on the 43 cases. Cerebral blood flow was decreased in cases with cerebrovascular diseases. This is proved to be the result of decrease of both blood flow and relative weight of grey matter. Blood flow of slow phase (representing white matter) is insignificantly decreased. Whereas blood flow of grey and white matter shows increase during 4% carbon dioxide inhalation.
3) Advantage of this simplified method was discussed.View full abstractDownload PDF (437K) -
Mitsuo MIYAHARA, Tadashi UEDA1968 Volume 9 Issue 4 Pages 359-367
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESS1) In 15 cases of ischemic heart disease (5 cases of type I of the WHO classification, 6 cases of type III and 4 cases of type IV), pyridinolcarbamate (Anginin) (750 to 2, 250mg./day) was given orally for 2 to 6 weeks to determine the effect.
2) In subjective symptoms, a positive effect was obtained in 9 of 11, while 4 of 14 showed a positive effect in ECG findings (cases without symptoms or findings before administration were excluded). In type I (WHO classification) subjective symptoms improved in all of the 5 cases, and ECG findings improved in 3 cases. In type III, on the other hand, subjective symptoms improved in 4 of 6 but ECG findings improved only in 1. No effect was seen in 4 cases of type IV.
3) As side effects, headache and a sensation of chest compression were seen in one case each. No other side effects were seen under the experimental conditions of the present study.View full abstractDownload PDF (438K) -
Takeshi ASANO1968 Volume 9 Issue 4 Pages 368-392
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESS(1) In order to study the relationship between the energy metabolism via TCA cycle and amino acid metabolism as well as protein synthesis, C14-labelled substrates were used for tracer experiment.
(2) Considerable C14O2 formation was noted from carbohydrates such as acetate-1-C14, pyruvate-1-C14, and pyruvate-3-C14, while a smaller amount of C14O2 was produced from amino acids such as glycine1-C14, alanine-1-C14, and glutamic acid-1-C14. Since glutamine-C14(U) was a universal type, a direct comparison with other labelled substrates was not possible, but a considerable amount of C14O2 production was noted.
(3) The transfer from acetate-1-C14 to glutamic acid, from pyruvate3-C14 to alanine and glutamic acid suggests the presence of the process of formation of glutamic acid from TCA cycle in the myocardium.
(4) Comparison between pyruvate-1-C14 and pyruvate-3-C14 revealed more transference of -3-C14 to amino acid.
(5) The carbon chains of glycine, alanine, and glutamic acid were transferred into other amino acids in the myocardium. Glutamine was also changed into many amino acids, and the transfer to glutamic acid was especially pronounced.
(6) The increase in C14O2 production from carbohydrate and glutamine through digitalis administration might suggest the facilitation of the utilization of these substrates by digitalis.
(7) Administration of ammonia inhibited oxidation of pyruvate3-C14.View full abstractDownload PDF (1178K) -
Isaomi KAKU1968 Volume 9 Issue 4 Pages 393-403
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSIn the present experiment, the incorporation ratios of glycine-2-C14 into nucleic acids and proteins extracted from various subcellular fractions were determined in the left ventricular hypertrophy and cardiac failure induced by aortic constriction.
1) The specific radioactivity of DNA increased only in the cardiac failure.
2) The so-called m-RNA was activated at an early stage and late stage of aortic constriction. The late stage meant the early stage of ventricular failure.
3) The mitochondrial and nuclear RNA were activated only in the compensated hypertrophy.
4) The incorporation ratio of microsomal, contractile proteins were considerably high in the hypertrophied muscle, but returned to normal in failing muscle.
5) The mitochondrial, cytoplasmic, and nuclear proteins showed high specific radioactivity only during compensated stage.
6) The results obtained were discussed concerning the mechanism of cardiac hypertrophy and failure.View full abstractDownload PDF (653K) -
Ludwig BETTE, Jürgen EBELING, Tohru KOBAYASHI1968 Volume 9 Issue 4 Pages 404-410
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe biplane cinefluorography has been used for 320 cardiac patients. With the selective injection and the 9 inch image intensifier, this method makes surely smaller radiation loads to the patient. The transistor control in this apparatus takes an extreme correct activity. The external pulsing is not necessary to adjust the radiographic exposure factors before the injection. The television connecting with this apparatus is possible to use its magnetic image and to fix easily the position of the catheter tip. By this method a position change of patients is not necessary during examinations.
Our biplane cinefluorography has many remarkable advantages in comparison with other methods, especially for infants and small children, but also for certain congenital and acquired heart and coronary diseases of adults.View full abstractDownload PDF (718K) -
Masaya SUGIURA, Ryozo OKADA, Tateo IIZUKA, Shin-ichiro OHKAWA, Hiroyuk ...1968 Volume 9 Issue 4 Pages 411-419
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSTwo cases of septal perforation due to acute myocardial infarction were reported. The first case was typical and the second case was unusual, in which a perforation was produced by a small isolated septal infarction due to occlusion of a small branch of the right coronary artery (ramus ventriculi dextri posterior). The pathogenesis was discussed. The specific combination of conduction disturbance with right bundle branch block and left axis deviation in the second case was explained by connective tissue changes in the annulus fibrosus due probably to aging process.View full abstractDownload PDF (3074K) -
Tsuguya SAKAMOTO, Masao NAGATANI, Zen'ichiro UOZUMI, Hideo UEDA1968 Volume 9 Issue 4 Pages 420-430
Published: 1968
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSAn acquired stenosis of pulmonary artery caused by benign cystic teratoma in a 22-year-old female is described. The pulmonary artery stenosis was manifested by the precordial systolic murmurs, distinct pulmonary artery-right ventricular pressure gradient, loud systolic murmurs in the pulmonary artery, and the characteristic picture of compression of the artery evidenced by pulmonary arteriogram. The removal of the tumor resulted in the acquired pulmonary regurgitation of significant degree. Short review of the literature was made and the complexity of the cardiac murmur was discussed.View full abstractDownload PDF (4767K)
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