Journal of Japanese Society of Oral Oncology
Online ISSN : 1884-4995
Print ISSN : 0915-5988
ISSN-L : 0915-5988
Volume 15, Issue 1
Displaying 1-4 of 4 articles from this issue
  • Takeo Nagai, Hidenori Nakamura, Hitoshi Yoshimura, Shinichi Naito, Yas ...
    2003 Volume 15 Issue 1 Pages 1-6
    Published: March 15, 2003
    Released on J-STAGE: May 31, 2010
    JOURNAL FREE ACCESS
    We report a rare case of adenoid cystic carcinoma with malignant transformation from pleomorphic adenoma 24 years after primary surgery. The patient was a 60-year-old man who was admitted for treatment of a tumor of the right upper gingiva. He had previously undergone two operations for a right lacrimal gland tumor. In the f irstsurgery, the tumor was removed by Krönlein's operation and histology of this tumor showed a pleomorphic adenoma. Twenty-four years later, he complained of exopthalmos of the right eye. Computed tomography and magnetic resonance imaging revealed that a tumor occupied the superior temporal portion of the right orbit and extended into the cranial cavity. Histopathological diagnosis of this tumor at the second operation was adenoid cystic carcinoma. After 10 months, however, the tumor grew into the maxillary sinus and oral cavity. The patient received radiotherapy and three courses of superselective intra-arterial chemotherapy. Although the tumor was reduced temporarily, it gradually became larger and eventually led to death.
    In rare instances, pleomorphic adenoma can undergo malignant transformation, particularly following incomplete and frequent surgical removal.
    We reported here such a rare case.
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  • Kunichika Yamamoto, Kazuhiko Ohgi, Jun-ichi Yasumoto, Yuichiro Imai, M ...
    2003 Volume 15 Issue 1 Pages 7-12
    Published: March 15, 2003
    Released on J-STAGE: May 31, 2010
    JOURNAL FREE ACCESS
    A case of spontaneous regression of malignant lymphoma (ML) is presented.
    An 80-year-old woman visited our hospital with a swelling at the right upper gingiva. She had a 30×45mm mass, part of which was ulcered on the gingiva. CT scan and panoramic radiographs showed bone resorption of the right maxilla. Swelling of bilateral lymph nodes without tenderness was observed. Pathological examination of a biopsy revealed malignant lymphoma (diffuse large B-cell lymphoma), (WHO classification), Stage II E. However, spontaneous regression of the ML was occurring after 3 months without any specific treatment. The patient has shown no evidence of recurrence as of 1 year 6 months since the first visit.
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  • Yasuto Yoshihama, Akiyoshi Nishiyama, Yosuke Yamada, Takuji Kimura, Hi ...
    2003 Volume 15 Issue 1 Pages 13-19
    Published: March 15, 2003
    Released on J-STAGE: May 31, 2010
    JOURNAL FREE ACCESS
    Patients in the terminal stage of oral cancer often die of bleeding from primary or metastatic neck lesions. These patients frequently have a very low quality of life.
    We report three cases of terminal oral cancer patients with bleeding, who received arterial embolization.
    Two out of the three cases, except one who died on the fourth day after embolization, were assessed before and after arterial embolization using the Karnof sky Performance Status scale (KPS) and serum albumin (Alb) .
    Consequently, each patient improved in KPS and Alb after embolization, and quality of life (QOL) of the two patients was better after arterial embolization.
    We consider that arterial embolization was useful for improvement of QOL of such terminal cancer patients with bleeding from primary or metastatic neck lesions.
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  • Hidehiko Noji, Sadao Okabe, Kazuhiro Yagihara, Toshiyuki Izumo
    2003 Volume 15 Issue 1 Pages 21-24
    Published: March 15, 2003
    Released on J-STAGE: May 31, 2010
    JOURNAL FREE ACCESS
    Recently, the number of patients undergoing bone marrow transplantation (BMT) for various hematopoietic disorders has increased gradually. It has been reported that the risk of occurrence of solid cancers as liver and head and neck cancers is high among such patients. We report on a case of tongue cancer in a youth who had undergone BMT 7 years before.
    The 18-year-old man first visited our hospital with a mass on the left side of the tongue. He had suffered acute lymphatic leukemia (ALL) at 11 years old and underwent BMT after chemotherapy and radiotherapy. He developed acute graft versus host disease (GVHD) after BMT and his clinical features progressed to chronic GVHD.
    A number of patients who undergo BMT receive a preparative regimen combining chemotherapy with total body irradiation (TBI) . It is suspected that these therapies induce the mutation of the host-gene and that local factors in the host organs damaged by chronic inflammation in GVHD may contribute to the development of solid cancers. It is suggested that follow-up in the oral cavity is needed at regular intervals in patients after BMT.
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