The Japan Society for Oral Tumors originated 10 years ago, at the Meeting for Oral Tumors, held at Oita Medical University on February 26, 1983.
These ten years are characterized by three periods: the Meeting (1983-85), the Society for the research of oral tumors (1986-88), and the Society for Oral Tumors (1989-until present) . In each period, academic meetings, conferences or congresses were held and journals were published. The records of these conferences and congresses and the journals have been reviewed already.
The number of society members, including those from the meeting period, increased from 69 in 1983 to 991 in 1992.
The Journal of Japan Society for Oral Tumors (abbreviated J Jpn Soc Oral Tumor) is presently published three times a year. However, society members are keen for the journal to be published four times a year, and it appears that this will soon be the case.
Since the Meeting for Oral Tumors in 1983, the society has upheld that all members should have the right to present the results of their scientific research, and be able to discuss research problems with other members democratically and on equal terms. If a problem is not resolved in a single session, it can either be discussed without time limitation or be given first preference at the next congress.
All people who have an academic interest in the research of oral tumors throughout Japan are eligible to participate in the society and the congress. In the near future, the society intends to expand not only nationally, but also internationally to include participants from other countries.

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Brachytherapy has become the standard method of treatment for cancer of the tongue. However, indication of the brachytherapy is limited by the size and site of the tumor. In an effort to improve tumor control and preserve the function of the tongue after surgery, we administered preoperative brachytherapy to four patients with advanced cancer of the tongue (two females aged 35 and 75 and two males aged 51 and 55 years) . We performed the brachytherapy to debulk the tumor at the center of the tongue, and restricted surgical resection of the primary focus to hemiglossectomy. The postoperative tongue function was good in all cases. Follow-up ranges from 1.8 to 7.6 years. All four patients are still alive, and the cancers have not recurred.

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During a fifteen year period from May 1976 to December 1990, we treated nineteen primary patients with squamous cell carcinoma of buccal mucosa at the Department of Oral Surgery, Tokyo Metropolitan Komagome Hospital. The average age of the patients was 70.6 years. This study analyses the treatment and results.
(1) TNM staging of the series after the UICC recommendation revealed that the majority of the patients were in advanced stages T3 and T4. Of these cases, 62.3% were NO, and all cases were M0.
(2) We chose two types of therapeutic modality for the initial treatment: the surgery group and irradiation group. Nine cases (50%) were treated by radiotherapy alone, two cases by a combination of irradiation therapy and surgery, and three cases by surgery alone. The primary tumor control rate for each type of therapy was 44.4%, 0 %, and 100%, respectively. By staging, stage III was 37.5% and stage IV was 100%. By location, buccal mucosa was 57.1% and retromolar area was 50.0%.
(3) The five-year cumulative survival rates were 55.1% in the 19 cases of buccal mucosa carcinoma (T1: 66.7%, T2: 64.8%, T3: 34.3%, T4: 53.3%) . The surgery group showed a higher survival rate (76.5%, surgery alone was 100%) than the irradiation group (36.8%, radiotherapy alone was 40.9%) .

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Of the 303 patients with head and neck cancer who visited our clinic from 1979 to 1991, 14 had squamous cell carcinoma (SCC) of the maxillary sinus and 14 had SCC of the maxillary gingiva, hard palate or maxillary intraosseous SCC.
Though most of the patients with maxillary sinus SCC bore advanced tumors such as T3 or T4 (UICC, 1987), we found metastasis in the cervical lymph nodes at the first visit in only one out of 14 patients, which was of significantly lower frequency than in patients with SCC of the maxillary gingiva, hard palate or maxillary intraosseous SCC. Most of the patients with maxillary sinus SCC was treated in combination with surgery, intraarterial chemotherapy, and radiotherapy. Half of them (7/14) are living without tumors, and we calculated the 5-year survival rate to be 52.1% according to the Kaplan-Meier method. W e have been treating the patients with maxillary sinus SCC in combination with intraarterial chemotherapy with Cisplatin or Carboplatin before surgery, fractional radiotherapy of 20 Gy and radical resection since 1987 and have obtained relatively good results with these patients.

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We performed fifty-six immediate reconstructions following the radical resection of cancers of the oral cavity in 54 patients using 64 various cutaneous and musclocutaneous flaps during 1977 to 1990. W e conducted a retrospective analysis of the cases and the clinical studies.
Thirty-two patients were primary cases (Stage II : 5, Stage III : 8, Stage IV : 19) and 22 were secondary (recurrent) cases. The primary sites of the cancer were the tongue in 20 cases, the lower gingiva in 12 cases, the floor of the mouth in 10 cases, the buccal mucosa and oropharynx in five cases, and one case each in the upper gingiva and submandibular gland. A pathological diagnosis revealed that fifty-one cases had squamous cell carcinoma, two cases had salivary gland carcinoma, and one case had undifferenciated carcinoma. The size of the excisions were varied according to the primary site and tumor stages. All reconstructive cutaneous or musclocutaneous flaps were composed of pectoraris major musclocutaneous flap in 31 cases, deltopectoralis flap in 18 cases, lattissimus dorsi musclocutaneous flap in seven cases, free radial forearm flap in five cases, and sternocleidomastoid musclocutaneous flap in two cases. The mean operation time was eight hours and 50 minutes, total blood loss was 1, 493 grams. The complete survival rate of reconstructed flaps was obtained in 71.4% of these cases. W e followed up these cases two to 15 years after the operation. The five year cumulative survival rate of all primary cases was 51.7%, that of all secondary cases was 24.1% that of total cases 42.5% according to Kaplan-Meier's method.
From the above results, we concluded that combined resection and reconstructive surgery is an effective form of therapy for advanced oral cancers. The problems yet to be solved are how to reduce the number of recurrent cases, the developement of effective chemotherapy for metastases, the detection of double cancer in the early stages, the development of a functional reconstruction following the resection of oropharyx, and the development of biomaterials.

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To the patient with tongue carcinoma (T4N0M0) who received the combination therapy of CBDCA and PEP, we administrated 75 pg of G-CSF every two days to prevent the granulocyte values of the blood from decreasing. We were able to maintain the granulocyte values above the normal range. However, the platelet values decreased during courses 4 and 5 of chemotherapy. We were therefore forced to reduce the dosage of anticancerous agents.

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Adenoid cystic carcinoma (ACC) is an uncommon tumor that may occur in head and neck. However, case reports of ACC occurring in the sublingual gland are rare. This paper reports on a case of ACC that occurred in the sublingular gland of an elderly man.
An 80-year-old male whose chief complaint was paralysis and the induration from his left oral floor to the tongue was referred to our department. We found an elastic, hard fixed tumor measuring approximarely 27×15 mm in his left oral floor. Clinically, we diagnosed the tumor as a malignant tumor of oral the floor. A pathological investigation at biopsy was ACC. Under general anethesia, we performed the upper neck desection and local wide resection by the tracheotomy. During the operation, we resected the lingual and sublingual nerve for susepectednerve inversion. In addition, we found submandibular and submental lymph node metastasis, but limited desection of the neck to the upper neck region due to the patient's age. The surgical defect was reconstracted by the residual tongue. We chose postoperative radiation therapy. We are able to control local region and cervical lymph nodes but discovered multiple lung metastasis in a postoperative examination.
A pathological investigation of the surgical specimen was ACC occurring in the sublingual gland with lymph node metastasis, venous invasion and perineural invasion.
Eighteen cases (including this case) of ACC occurring in the sublingual gland have been reported in Japan to date. Usually, this tumor is wide resected with radical neck desection. However, we performd local wide resection and upper neck desection in an elderly patient to prevent postoperative problems and functonal lose.

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