Purpose: To determine how nurses perceive the need for advance care planning (ACP) for chronic heart failure with patients and their families. Methods: A questionnaire survey was administered with 427 nurses who were affiliated with implantable cardioverter-defibrillators and resynchronization therapy. The survey included 13 items related to the need for ACP for simulated advanced heart failure cases with patients and their families. Results: Valid Responses were obtained from 207 nurses. On out of all items, the least proprtion of participants (51%) responded “giving predictions about functional prognosis and life expectancy” should be performed with patients. The participants’ perceptions regarding 8 items, which included the items on communication about prognosis, reflected their belief that ACP should be performed with family members rather than the patient. It was found that participants with certification in chronic heart failure nursing were more likely to respond in favor of ACP being performed with the patients in relation to 7 items, which included “ask about what has been important in one’s life”, and being performed with the family in relation to 10 items that included “ask the family what kind of life you want the patient to have hereafter”, as compared to other nurses. Conclusion: Regarding ACP, it is suggested that nurses are careful in discussing prognosis with patients, and certified nurses tend to attach importance to the individualities and values of patients and their families.

Purposes: We prospectively examined the effects of “instruction for near death” by doctors to improve communication and difficulty in end-of-life care in acute general wards. Methods: A non-randomized controlled trial was conducted to evaluate the communication between pre-treatment group and the group with and without the “instruction for near death” in the end-of-life period by Japanese version of Support Team Assessment Schedule (STAS-J). We also compared the difficulty of end-of-life care before and after the trial. Results: The “communication between professionals” in STAS-J was 0.46±0.53 in pre-treatment group (n=71), 0.18±0.39 in the instruction group (n=34) and 0.66±0.48 in the non-instruction group (n=44) (p<0.001). The “family anxiety”, the “family insight”, “communication between patient and family” and “communication professional to patient and family” in STAS-J were not significantly different between the groups. The questionnaire of difficulty of end-of-life care showed no change in both doctors and nurses. Conclusions: The “communication between professionals” was improved in the group with the “instruction for near death”. The difficulty of end-of-life care was not reduced, and it did not contribute to family anxiety and communications.

Purpose: To elucidate the actual state of difficulties and related factors of nurses in caring for patients with recurrent and metastatic malignant musculoskeletal tumor. Methods: The subjects were 315 nurses from 12 institutions that treat malignant musculoskeletal tumor. We researched the difficulties of nurses regarding cancer nursing and care of patients with malignant musculoskeletal tumor. We examined the related factors by multiple regression analysis. Result: 165 nurses responded (effective response rate 52.4%). Among “Nurses’ difficulty with cancer care”, the level of difficulty regarding communication was the highest and in own knowledge/technology, system/regional cooperation was also high. Among “Nurses’ difficulty with care for patients with malignant musculoskeletal tumor”, there was a high degree of difficulties regarding the target characteristics of care. Related factors were facility characteristics, nursing experience, nursing experience of musculoskeletal tumor, learning methods for musculoskeletal tumor nursing, and multi-professional conferences. Conclusion: Nurses caring for patients with malignant musculoskeletal tumor have specific difficulty due to total pain, age of onset, and rarity. Educational support based on related factors is therefore required.

The aim was to explore existential suffering n physicians caring for terminally ill cancer patients. We performed qualitative analyses of 30 physician-reported descriptions of the clinical experience of caring for terminally ill cancer patients. Analyses were conducted using descriptive phenomenology to clarify the meaning of physicians’ experiences, guided by the three dimensions of Murata’s human being model. In their descriptions, all physicians mentioned existential suffering related to incompetence, and three themes were identified: 1) physicians who focus on the limitations of what they can achieve with curative or palliative treatment feel a sense of incompetence; 2) physicians who focus on difficulties in caring for patients with existential suffering feel a sense of incompetence; and 3) physicians who focus on environmental factors, such as work overload and insufficient communication skills training, experience a sense of incompetence. Physicians experience a sense of incompetence when they face treatment limitations and/or difficulties in caring for patients with existential suffering.

Objective: We investigated the association between catastrophizing with regard to numbness and pain, subjective symptoms, upper extremity function, and disability in cancer patients with chemotherapy-induced peripheral neuropathy (CIPN). Method: We evaluated catastrophizing (pain catastrophizing scale [PCS] total score, rumination, helplessness, magnification), subjective symptoms of numbness and pain, upper extremity function, and disability in patients with hematological malignancy and gastrointestinal cancer who developed upper extremity CIPN. We calculated the Spearman’s rank correlation coefficient to determine the strength of the association. Result: A significant association was observed between catastrophizing and disability; however, upper extremity function was not significantly association with catastrophizing. Based on the PCS subscale scores, only rumination was significantly association with subjective symptoms. Conclusion: Functional assessment and approaches may not be sufficient to improve the activities of daily living in cancer patients with upper extremity CIPN, and assessment and approaches to cognitive aspects, such as catastrophizing, should also be considered.

The aim of this study was to investigate the practical abilities of discharge planning nurses to support discharge of terminal cancer patients. A survey was mailed to 477 discharge planning nurses (DPNs) who were employed at 120 designated regional cancer centers in Japan. Responses from 198 (valid response rate 41.5%) DPNs were subjected to analysis. The median number of years of DPN experience of the subjects was 2.5 years, and 90.2% of them had more than 10 years of nursing experience. Among the discharge planning abilities, “To Coordinate Post-discharge Care Balance” was significantly higher in the group with more nursing experience and in the group with longer DPN experience; “To Estimate Post-discharge Care Balance” and “To Prepare for Transition from the Hospital to a Care Facility” was significantly higher in the group with longer DPN experience and in the group with more experience working in home and community care. But “To make an agreement with the patient and their families” was not significantly different for experienced DPNs. It was suggested that in order to improve the quality of discharge planning, it is necessary to create a system that allows staffing based on individual experience and sharing of knowledge and experience of veteran DPNs.

In recent years, the system for providing home medical care and palliative care has been improved, and the number of cancer patients who are treated at home until the end is increasing. The aim of this study was to investigate the circumstances of cancer patients who died at home and the presence of doctors and nurses at the moment of death. We conducted a prospective survey of end-oflife cancer patients receiving home visits from home care and palliative care clinics in Japan from 1st July to 31st December 2017. During the study period, we analyzed the mortality status of 676 patients who died in their homes, serviced by 45 clinics. Of these patients, 91% were living with families, 49% died on holidays or at night, and the doctor and nurse was present at the time of death in only 5.6% and 9.9% of cases, respectively. Most of the patients who died at home lived with their families, with few doctors and nurses present at the time of their patients’ death.

Those involved in end-of-life care need to understand the patient’s view of life and values, and support them so that they can approach the end of their lives in a way that suits them, and this requires sufficient communication. We report a deaf-mute patient who developed advanced lung cancer during treatment of chronic myeloid leukemia. The communication with him was difficult for those who did not use sigh language routinely, but through trial and error, we tried to build a good relationship through nonverbal communication as well as sign language and written communication. It was necessary to recognize and understand that deaf-mute people have different living environments and communities and have their own language and culture. These experiences can be utilized for the treatment of cancer patients in daily clinical practice, and it is considered that the attitude of the medical worker to approach the patient is necessary for mutual understanding.

Few pregnant women are prescribed oxycodone for cancer pain. Here, we report a case of neonatal abstinence syndrome in an infant born to a woman using oxycodone long term for cancer pain. During pregnancy, rather than the expected effects on pregnant women for oxycodone use, fetal growth was also favorable. However, the infant presented with respiratory failure after birth and required ventilator management. In addition, the infant required treatment for neonatal abstinence syndrome.

We reported a clinical case in which decreased concentration of hydromorphone citrate in subcutaneous infusion therapy led to the improvement of subcutaneous induration. A subcutaneous infusion therapy with hydromorphone citrate was initiated in a 60-year-old female pancreatic-cancer patient with back pain. A subcutaneous induration has emerged when the infused concentration of hydromorphone citrate was increased from 0.17% to 0.83%. After the reduction in its concentration (0.28%), that subcutaneous induration has improved. For the alleviation of nausea and sedation, administration of haloperidol and midazolam were added at day 61 and day 70, respectively, with keeping the low concentration (≤0.28%) of hydromorphone citrate. Under this condition, further occurrence of subcutaneous induration was not observed. As a result, we suggested that the concentration of hydromorphone citrate in subcutaneous infusion therapy determined the onset of subcutaneous induration.

We encountered a case where opioids were effective for excessive sweating caused by secondary generalized hyperhidrosis associated with cancer. ​​A 64-year-old woman diagnosed with metastatic renal cell carcinoma was admitted to the palliative care unit with right hip pain caused by bone metastasis and sudden excessive sweating. An increased dose of fentanyl transdermal patch provided pain relief. Excessive sweating seemed to have occurred due to neoplastic fever initially, but antipyretic analgesics and steroids were ineffective. Prophylactic use of immediate-release oxycodone provided excessive sweating relief. Finally, we consider that hypothalamus and fentanyl transdermal patch were involved in excessive sweating. Opioids may suppress sweating by acting on the hypothalamus.

Recently, the importance of terminal care has been emphasized in studies of patients with malignant brain tumors. Healthcare professionals should have knowledge of symptoms caused by brain tumors when treating patients in the terminal phase. This study aimed to investigate the data collection method, evaluation time, and symptoms of patients with brain tumor in the terminal phase through literature search. Seven papers were extracted by a literature search. Data collection methods included collecting information from medical records (4 papers), questionnaire (2 papers), and telephone survey (1 paper). Evaluation times ranged from 46 days to 1 week before death. Symptoms presented by patients with malignant brain tumors in the terminal phase could be classified according to disease-specific symptoms and general symptoms presented by patients with other types of terminal cancer. The most commonly reported disease-specific symptoms were disturbance of consciousness (4 papers), seizures (7 papers), dysphagia (6 papers), and headache (6 papers). The proportion of patients with dysphagia increased as they approached the end of life. These results suggest that the data collection method and evaluation time differ depending on the previous studies and that patients with brain tumors in the terminal phase are likely to present disease-specific symptoms.

Introduction: Our palliative care staff began the support activity in opioid introduction for outpatients with cancer at Komaki City Hospital in March 2018, because it was difficult to make them understand about proper use of opioid analgesics and misinterpretation about abuse at the time of opioid introduction in outpatient settings. This study aimed to evaluate the effects of the activity (patient education on pain control, telephone follow up, and assessment of the symptom). Method: Outpatients with cancer receiving strong opioids for pain relief from January 2017 to March 2019 were eligible. We retrospectively investigated the difference of the variables between baseline and after the activity as follows; the ratios of prescribing immediate-release opioids, antiemetics, and laxatives when opioids were prescribed and side effects due to opioid analgesics appeared. Results: The study included 122 patients. The prescribing ratios of immediate-release opioids antiemetics and laxatives all increased from 90.7 to 98.5%, from 63.0 to 70.6%, and from 61.1 to 70.6%, respectively. The side effect incidence due to opioids with STAS-J 2 or more decreased from 12 (22.2%) to 9 (13.2%). Discussion: The activity could contribute to the provision of drug treatments and counselling needed for opioid therapy.