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Volume 11, Issue 1
Displaying 1-7 of 7 articles from this issue
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Hitoshi FUJITA, Etsuko SAITO, Kenshi SUZUKI, Akiyoshi WADA1970 Volume 11 Issue 1 Pages 1-8
Published: March 01, 1970
Released on J-STAGE: August 29, 2006
JOURNAL FREE ACCESSThe effect of illumination with visible light in the presence of dye on pneumococcal transforming DNA was investigated and the following results were obtained. (1) The DNA was inactivated under oxygenated condition. (2) The dye bound to DNA was exclusively involved in the inactivation process. This conclusion was derived from the following findings: (a) The action spectrum for the inactivation was consistent with the absorption spectrum of the bound dye rather than that of free dye. (b) The initial rate constant of inactivation ran parallel with the amount of bound dye. (3) The length of illuminated DNA was reduced as revealed by the increase in rotary diffusion constant.View full abstractDownload PDF (346K) -
Hitoshi FUJITA, Kenshi SUZUKI1970 Volume 11 Issue 1 Pages 9-13
Published: March 01, 1970
Released on J-STAGE: August 29, 2006
JOURNAL FREE ACCESSThe photodynamic inactivation of Escherichia coli strain 15T-, B/r and B was studied using acridine orange and methylene blue as sensitizers. The sensitivity was strongly dependent on the growth phase, namely, the cells at the stationary phase were extremely resistant. Parallel to the sensitivity to ultraviolet or X-rays, strain B/r was less sensitive than strain B. There was no recovery of strain 15T- in a liquid medium (M9) after illumination in the presence of acridine orange. When chloramphenicol was added to this medium, the inactivation proceeded further during the incubation. The syntheses of DNA, RNA and protein were greatly inhibited.View full abstractDownload PDF (200K) -
Muneyasu URANO, Norimoto TANAKA1970 Volume 11 Issue 1 Pages 14-19
Published: March 01, 1970
Released on J-STAGE: August 29, 2006
JOURNAL FREE ACCESSMulti-target response law in cellular radiation biology has been extended to clinical dose fractionation schedules. Hypoxic cell component in tumors makes this extention very confused. Hall promoted rethinking of the oxygen effect in the radiotherapy. This paper presents this rethinking in terms of TCD90 or 90% tumor control dose.View full abstractDownload PDF (261K) -
Kouichi ASAMI, Ikuo YASUMASU, Ross L. SHOGER, Akiko FUJIWARA1970 Volume 11 Issue 1 Pages 20-23
Published: March 01, 1970
Released on J-STAGE: August 29, 2006
JOURNAL FREE ACCESSUnfertilized eggs of the sea urchin, Hemicentrotus pulcherrimus, were irradiated with 60Co γ-rays. Incorporation of 14C-leucine into the protein fraction increased after 25 krads of irradiation. A slight acceleration of glycolysis by irradiation was indicated by the measurement of glycolytic intermediates both in unfertilized and fertilized eggs. However, the degree of activation of glycolysis with irradiation was much less than that follows fertilization. However, the abnormal accumulation of fructose diphosphate after irradiation, which has been observed in tumor cells or thymocytes, was not observed in the eggs and was discussed in relation to cellular radiosensitivity.View full abstractDownload PDF (187K) -
Kazuo TAKADA, Minoru FUJITA, Masashi SUZUKI1970 Volume 11 Issue 1 Pages 24-31
Published: March 01, 1970
Released on J-STAGE: August 29, 2006
JOURNAL FREE ACCESSCerium-144 was injected intravenously into rats as the chloride with different amounts of carrier. After a single injection the whole body retention, daily fecal and urinary excretion, and tissue distribution were studied during about a month. The following results were obtained. Addition of carrier suppressed the early urinary excretion which was observed with carrier free Ce-144. A large amount of carrier markedly suppressed the fecal excretion which was the main excretory route of cerium. In general, the maximum value of fecal excretion was observed about a few days after injection, although it depended on the carrier level, and the whole body retention curves showed sigmoidal patterns. As the amounts of carrier increased, Ce-144 decreased in the bone and kidney, and increased in the liver and spleen. It seemed that, when the carrier level was low, intravenously injected Ce-144 showed relatively ionic nature but as the carrier increased it showed more colloidal nature.View full abstractDownload PDF (310K) -
Yutaka NAGAYA, Kiyoshi NAKAMURA1970 Volume 11 Issue 1 Pages 32-43
Published: March 01, 1970
Released on J-STAGE: August 29, 2006
JOURNAL FREE ACCESSA model was established for estimation of vertical transport of Sr-90 and Cs-137 in surface layer of the seas.
In the upper 500 meters of the open seas around Japan, approximate residence times concerning vertical transport are estimated as 5 years for Sr-90 and 3 years for Cs-137.
For the coastal waters, the residence time seems to be lower than those on open seas. Slight differences of the rates of vertical transport are observed among three regions and between Sr-90 and Cs-137.View full abstractDownload PDF (444K) -
Kazuhisa KAMEDA, Makoto SHIMIZU, Yoshio HIYAMA1970 Volume 11 Issue 1 Pages 44-52
Published: March 01, 1970
Released on J-STAGE: August 29, 2006
JOURNAL FREE ACCESSIt was previously reported that stable and radioactive zinc concentration in water changed during the tracer experiment for the uptake of zinc in marine organisms. In the present study, the cause of the change in zinc and zinc-65 concentration in water was investigated, and the followings were revealed: (1) zinc in dust contaminates the rearing water for tracer experiment, (2) the presence of organisms changes the zinc content in water, and (3) the reduction in zinc-65 concentration in water corresponds to the uptake amount by shellfish.View full abstractDownload PDF (323K)
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