[in Japanese]

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By means of Motokawa's Method of electric flicker the authors examined the change in electric flicker values (EFV) of 6 healthy males due to alcohol drinking with and without oral administration of TAS (10mg) one hour in advance. As drinking alcohol, whisky and Japanese wine were chosen. EFV obtained after drinking whisky (40∼60cc) increased remarkably, but EFV obtained after whisky drinking combined with TAS administration did not show any marked increase and EFV showing increase, if any, soon returned to the initial value. As to EFV obtained after drinking Japanese wine (120cc, 150cc, 200cc and 300cc), of the 6 subjects, in 2 it increased remarkably, and their EFV after Japanese wine drinking combined with TAS administration showed decrease and returned rapidly to the initial value. In another 2 subjects EFV showed, after increase, only rapid return to the intial value by TAS administration. In the remaining 2 subjects EFV did not show any remarkable effects due to TAS administration, while in the same subjects, administration of TAS showed greater effects against drinking bigger amount of Japanese wine than a little of it, i.e. the larger the amount of alcohol the greater the effect of TAS.

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Progress during four years of the tuberculosis combined with pneumoconiosis was observed in 341 cases under chemotherapeutic treatment. Roentgenological classification of the type of the tuberculosis was done according to the agreement arrived at by the Council of Scientific Research, and that of pneumoconiosis according to the regulation of the Pneumoconiosis Act, 1960. The results are as follows. In cases without caverned defects rate of aggravation decreased as the age advanced, while those with such the rate was highest in the age group 50∼59 years. This may be due to the state of progress of underlying silicotic changes. The rate of aggravation after the lapse of two years of silicotuberculosis was 4.30% as against 3.28% in mere tuberculosis. Cases of silicotuberculosis with caverned defects and/or nodular shades showed higher aggravation rates than those without such, showing nearly twice as much rate of the latter. Cases with infiltrative tuberculosis showed aggravation rates over 15%, while those with fibrous tuberculosis was below 10%. In cases with exsudative tuberculosis chemotherapeutic improvements were especially marked, showing aggravation rates of only about 5%. Percentage distribution of the type of pneumoconiotic nodular shadows were: p₁ 4.3%, p₂ 8.7%, p₃ 14.8%, m₁ 19.3%, m₃ 35.7%. The aggravation rates were nearly in parallel with these percentages. In general, group m showed higher aggravation rates than group p, and group m₃ showed thehighest rate from the beginning.

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