Tack properties of crosslinked poly（n-butyl acrylate-acrylic acid）（ A） and crosslinked poly（2-ethylhexyl

acrylate-acrylic acid） random copolymers（ B） with an acrylic acid content of 5 wt％ as model pressuresensitive

adhesives（ PSA） were compared by the probe tack test. Measuring temperature and contact time

were varied in the range from 0 to 60 ℃ and from 30 to 1800 s, respectively. Tack was B > A both above 30 ℃

and contact time of 1800 s. Especially, the increase in the fracture energy of B was remarkable. Debonding behavior

during the probe tack test was observed using a high-speed microscope from side and upper directions.

The fibrillation of PSA at the edge of probe/PSA interface and the area in which fibrillation occurred were observed.

Both the fibril length and the area in which fibrillation occurred were B > A. The stress-strain curves

of PSAs were measured. The maximum stress was A > B and elongation was B > A. The degree of relaxation of

debonding stress by deformation of PSA was B > A. This is the reason why above mentioned tack and fracture

energy were higher for B than A.

It was found that among the bisphenol F type epoxy resins, the highly symmetrical 4,4ʼ-substituted compound（

p-BPF-E） gives a crystalline cured product with a melting point of 149.7℃. As a result of evaluating

the physical properties of the p-BPF-E cured product in the epoxy resin composition filled with alumina, the

thermal conductivity was 4.1 W/m·K（ Al2O3; 90 wt％）, which was about 1.3 times that of the amorphous cured

product. In addition, the p-BPF-E cured product had high thermal conductivity from room temperature to

around its melting point of 150℃, corresponding to its crystallinity. In addition, it was confirmed that it has a

heat distortion temperature of 154-163℃, low thermal expansion and low water absorption due to the crystallinity

of the cured product.

Endoscopic submucosal dissection（ ESD） has received much attention as a minimally invasive treatment for

endoscopic resection of early-stage gastrointestinal cancers in the esophagus, stomach, and colon. However,

there are severe complications caused by the inflammatory response after ESD. Although wound dressings

can be used to protect wounds, conventional wound dressings have problems such as poor tissue adhesion,

inflammation associated with degradation, and difficulty in delivering them to the wound site. In this study, we

developed tissue-adhesive particles by hydrophobic treatment of biopolymers and applied them to the wound

dressing material after ESD. Microparticles composed of hydrophobic gelatin derived from porcine or Alaska

pollock showed high tissue adhesion and stability in water for tissues under wet conditions such as gastrointestinal

tissues. The surface treatment of the particles also improved their hemostatic function. Furthermore,

we found that the particles could protect ulcers and inhibit inflammation in a porcine ESD model. The particles

may be useful as a medical material to prevent complications such as scar contracture, stenosis, perforation

and bleeding after ESD.