Miso has been said to have the potential to alleviate intestinal failure since ancient science. In this research, 28 kinds of
Miso samples were analyzed and LPS neutralization substrates were researched. First, their LPS neutralization activity were assayed. Elimination activity of No. 22
Miso sample produced in Nagano measured 85 %, four samples had between 50 and 80% LPS neutralization activity, and ten samples had between 19 and 50% of the activity. The others failed to show the activity. The No. 22
Miso sample, which had the most neutralization activity among the samples, also had the largest amount of soluble nitrogen at 0.48 %. The fluorescence of
Miso, which had LPS activity in the sample dying ANS reagent, had high values. The statistical analysis as a correlation analysis was carried out for LPS neutralization activity and other compounds in
Miso. LPS neutralization activity strongly related with soluble nitrogen in
Miso, and its coefficient R was 0.8329. It also had a relation with fluorescence dye using ANS in
Miso. Therefore, LPS neutralization activity had a relation with hydrophobic peptide in
Miso. It is scientifically obvious that
Miso neutralized LPS having the potential for inflammation the in the intestinal tract.
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