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Volume 30, Issue 2
Displaying 1-6 of 6 articles from this issue
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Present Status and ProblemsYasushi Takagi2001 Volume 30 Issue 2 Pages 61-67
Published: June 30, 2001
Released on J-STAGE: November 27, 2012
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Yoshihiro Ashihara2001 Volume 30 Issue 2 Pages 68-76
Published: June 30, 2001
Released on J-STAGE: November 27, 2012
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Katsuhiko Kuwa2001 Volume 30 Issue 2 Pages 77-85
Published: June 30, 2001
Released on J-STAGE: November 27, 2012
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Kaoru Satake, Keiichiro Enomoto, Haruhiro Muratsubaki2001 Volume 30 Issue 2 Pages 86-90
Published: June 30, 2001
Released on J-STAGE: November 27, 2012
JOURNAL FREE ACCESSLipoprotein lipase (LPL) activity in patients with lipid metabolism dysfunction has been analyzed by measuring plasma LPL which is liberated from blood vessels after heparin injection. However, heparin administration makes the application of this method as a routine test difficult. In this study, we determined LPL in serum as protein mass ELISA. We studied the correlation between LPL and lipids and other parameters associated with diabetes mellitus, using serum collected without heparin injection. The mean value of LPL of ambulatory medical examinees was 53.1 (20.1) ng/ml (n=155). Serum LPL correlated negatively with triglyceride and HbAlc. In insulin-treated diabetes and other hypoglycemic drug-treated diabetes, serum LPL correlated negatively with triglyceride. When olive oil was administered orally, serum LPL in 3 of 4 subjects increased and reached maximum levels at 4 hours. These results were similar to those of postheparin LPL activity (PHLA) previously reported. Therefore, serum LPL can provide an alternative to PHLA in the analysis of diseases associated with abnormal lipid metabolism.View full abstractDownload PDF (518K) -
Study of the Usefulness of Bone Metabolism IndicesTadayuki Iida, Fumiko Ishizaki, Masumi Hayashi, Hiroaki Ishikawa, Tada ...2001 Volume 30 Issue 2 Pages 91-99
Published: June 30, 2001
Released on J-STAGE: November 27, 2012
JOURNAL FREE ACCESSChange in bone metabolism is one of the factors related to bone volume decrease, with bone volume decrease becoming remarkable for a period of ten years after menopause. Using female subjects with known dates of menopause but without past histories affecting bone mineral density, the present study was conducted to examine the effect of menopause on bone metabolism indices and bone mineral density, and also to determine the usefulness of various bone metabolism indices such as urine pyridinoline, deoxypyridinoline, and N-telopeptides of type 1 collagen. The values of these bone metabolism indices following menopause were higher than those prior to menopause, and the values of Ntelopeptides of type 1 collagen showed the closest correlation to body mineral density of the lumbar vertebrae and the femur. This is because N-telopeptides of type 1 collagen have high bone specificity. It is therefore considered that N-telopeptides of type 1 collagen is the most useful as a bone metabolism index.View full abstractDownload PDF (1013K) -
Reiko Wada, Takayuki Matuto, Asako Matui, Miho Sakurai, Takasi Miida, ...2001 Volume 30 Issue 2 Pages 100-105
Published: June 30, 2001
Released on J-STAGE: November 27, 2012
JOURNAL FREE ACCESSIn spite of the usefulness of the examination of cerebrospinal fluid (CSF) in the diagnosis of diseases of the central nervous system, the reference intervals of the chemical constituents of CSF cannot be readily determined because the invasiveness of sampling procedures makes it difficult to gather a sufficient number of samples from healthy subjects. Instead we carefully chose samples from patients whose diseases did not seem to affect the contents of CSF, and estimated the reference intervals of total protein, albumin, glucose, IgG, β2 microglobulin, sodium, potassium, chloride, AST, LD, calcium, inorganic phosphate, apolipoprotein E, and sialic acid using the parametric method. Among them, the contents of total protein, albumin, IgG, β2 microglobulin, and apolipoprotein E tended to vary with age. Therefore age-stratified reference intervals have been estimated for these substances.View full abstractDownload PDF (658K)
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