The Journal of Japan Society for Laser Surgery and Medicine
Online ISSN : 1881-1639
Print ISSN : 0288-6200
ISSN-L : 0288-6200
Volume 8, Issue 2
Displaying 1-10 of 10 articles from this issue
  • [in Japanese]
    1987 Volume 8 Issue 2 Pages 1
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
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  • Shigeru SHOJI
    1987 Volume 8 Issue 2 Pages 3-7
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
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  • Haruka KUSAKARI, Toshio TONOUCHI
    1987 Volume 8 Issue 2 Pages 9-14
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese]
    1987 Volume 8 Issue 2 Pages 15-19
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
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  • Kenji HASHIMOTO, Kensuke NAKANO, Shigetoshi SHIODA, Hiroyuki WAKE
    1987 Volume 8 Issue 2 Pages 21-27
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    Recently various low power laser are developed and useful in treatment in medical and dental region. But the biological mechanism of these laser is not known in details.
    We would like to report on the results of our investigation of correlation between the thermogram and the effects of diode laser irradiation in the oral and maxillofacial lesion. The thermogram takes before the treatment and immediately, 5 minutes and 10 minutes after radiation.
    The diode laser irradiation has improved effects of the local circulation. The skin temperature was decreased in the hot area and increased in the cold area immediately after irradiation.
    Therefore it seemed that the diode lasertherapy was safety and available for treatment of nervous diseases, postoperative complications, imflammations and temporomandibular arthrosis.
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  • -Examination by Somatosensory Evoked Potentials-
    Yasushi IMAMURA, Masahito SUMITOMO, Hideki FURUYA
    1987 Volume 8 Issue 2 Pages 29-44
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    The treatment of trigeminal neuralgia, which is represented by acute pains of repetitive and idiopathetio nature, uses mostly an alcohol block of the peripheral nerves. The average effective period of an alcohol block is about 15 months, and in most cases acute pains recurred with sensory recovery. To establish a more effective nerve block, an application of the Nd YAG laser was devised that utilizes this laser's high transmissivity through tissues.
    A delicate laser probe was developed for the experiment, in which a laser beam is directed to the peripheral nerves through a small incised opening in the oral cavity. The purpose of the experiment was to objectively determine the effect of this new blocking method. The somatosensory evoked potential (SEP), a widely used index of sensation against stimulus, was measured under laser blocking and compared with that of an alcohol nerve block.
    Both the P1 and N1 waves disappeared immediately after the laser block was applied, and the waveforms were observed with no change in time that are similar to those seen after nerves are severed. The average effective period in 12 clinical treatments of trigeminal neuralgia using the new laser block was 23 months, and the longest was 56 months until 1987, June.
    The new Nd-AG laser block is clearly effective in treatment of trigeminal neuralgia.
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  • Toshimitsu Misaki, Haruo Hisazumi, Katsusuke Naito
    1987 Volume 8 Issue 2 Pages 45-52
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    Photodynamic therapy (PDT), using hematoporphyrin derivative (HpD) and red light (wavelength 630nm) of an argon-dye laser as the source of excitation energy was performed on 2 patients with non-invasive and papillary carcinoma of the penis and 2 patients with invasive penile carcinoma.
    These histological diagnoses were squamous cell carcinoma. The 4 patients received PDT 72 to 96 hours after i. v. injection of 2 to 3mg/kg HpD.
    Interstitial PDT was added to the 2 invasive carcinomas. The total light energy was adjusted to 60 to 300 Joules/cm2. Tumor necrosis was observed 1 to 2 days after PDT, and tumor size was reduced rapidly thereafter.
    Complete remission was obtained in the 2 papillary carcinoma patients.
    One of the 2 patients is alive with no evidence of disease for 40 months to date. The other patient died of multiple bone and pulmonary metastases 9 months after PDT without local recurrence. In the 2 invasive carcinoma patients, a small amount of residual tumor cells invading to the corpus cavernosum was observed after PDT. They died of multiple metastases 11 and 2 months after PDT respectively.
    Histopathological study of the tumor immediately after PDT showed a marked dilatation of the tumor vessels, bleeding in the stroma and degeneration of the nuclei of the endothelium. These findings suggested that vascular damage can be closely related to tumor destruction resulting from photodynamic effect.
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  • -THE GENERATION OF SINGLET OXYGEN AD THE ANALYSIS OF ITS DYNAMICAL PROCESS-
    Ichiro TANABE
    1987 Volume 8 Issue 2 Pages 53-67
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    Clinically, the photoradiative therapy by using laser radiation has been established as therapeutic method to cancer, but its fundamental theory of phototoxic has not been proved experimentally yet today. Since the 1970's, the energy transfer model from porphyrin to oxygen molecule has been advocated by Dougherty's group and singlet oxygen which was produced in this process has been regarded as the most important facer for photoradiative effect.
    In this reports, we made use of picosecond pulse Nd: YAG laser system for light source and measured life times of red fluorescences (wave length=630nm) from porphyrin and of infrared fluorescences from singlet oxygen (wave th=1.27μm) in various porphyrin solutions.
    Further more, for studying productive rate of singlet oxygen quantitatively, we analyzed temporal change of fluorescence in each process and calculate energy transfer rate from porphyrin to oxygen molecule by solving rate equation.
    In this results, the ratio of energy transfer which was given to oxygen molecule was only less than 10-2-10-3. So the majority of first exited energy was transformed to other process beside oxygen molecule. We considered this other process from two different view point, one was the nonradiative process in porphyrin molecule and the other was the reabsorption of energy by solvent.
    Thus, we must reflect other facer to make clear the fundamental each of photoradiative effect, but we think it is also important to confirm the production of singlet oxygen because there is possibility to destruct living body in small amount of singlet oxygen.
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  • 1987 Volume 8 Issue 2 Pages 69-89
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1987 Volume 8 Issue 2 Pages 92-107
    Published: 1987
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
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