The effects of repeated foot bathing in carbon dioxide-rich water on humoral regulation of physiological functions were studied.
Subjects were five aged persons (4 females and 1 male, 87.4±5.9 years old), who were visiting a geriatric intermediate care facility. Each subject immersed their lower legs in artificially produced carbon dioxide-rich water (800–1000 ppm) at 40–41°C more than twice a week for three months. Hematological and blood biochemical parameters were measured before and 3 weeks and 3 months after the beginning of the repeated foot bathing. Mean corpuscular hemoglobin concentration increased significantly and mean corpuscular volume decreased significantly after 3 weeks and 3 months. In addition, red blood cell count and hemoglobin concentration increased significantly after 3 months. There are no significant changes in plasma levels of Fe, ferritin, and erythropoietin after 3 weeks and 3 months. Total protein concentration and albumin increased, and aldosterone and K
+ increased significantly after 3 months.
These findings raise the possibility that the repeated carbon dioxide foot bathing affects various body functions not only regulated by autonomic nervous systems, but also regulated by humoral factors, such as hematopoietic functions, protein metabolism, and water-electrolyte metabolism.
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