Over the past few decades, an increasing number of studies have been done on the measurement of blood glucose. We developed a noninvasive system to measure blood glucose based on infrared spectroscopy (IR). With this system, we were able to measure the spectrum of the human finger by using Fourier transform infrared spectroscopy - attenuated total reflectance (FTIR-ATR). Furthermore, by using an individual calibration model based on partial least squares regression, we were able to measure human blood glucose. We describe the measurement results and assess the validity of the new system in this paper.