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Article type: Cover
2014 Volume 54 Issue 1 Pages
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Article type: Cover
2014 Volume 54 Issue 1 Pages
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Article type: Index
2014 Volume 54 Issue 1 Pages
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Article type: Index
2014 Volume 54 Issue 1 Pages
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
3-5
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
6-8
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Tatsuhisa Yamashita
Article type: Article
2014 Volume 54 Issue 1 Pages
9-10
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[in Japanese]
Article type: Article
2014 Volume 54 Issue 1 Pages
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Atsuko Koyama
Article type: Article
2014 Volume 54 Issue 1 Pages
12-19
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Psycho-oncology has been developed all over the world since its conception in the US in the 1970s and this plays an important role in the clinical oncology of today. In this paper, past findings regarding psycho-oncology are reviewed and the relationship between psycho-oncology and psychosomatic medicine is discussed. The role of psycho-oncology in each clinical stage ; three major psychological distress of cancer patients-adjustment disorders, depression and delirium ; and several psychosocial interventions aimed at improving of the quality of life (QOL) of cancer patients are outlined. The collaboration between psycho-oncology and psychosomatic medicine in both clinical and research fields should be promoted in order to improve the QOL of cancer patients, their family members and medical staff.
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Hironobu Inoguchi, Ken Shimizu
Article type: Article
2014 Volume 54 Issue 1 Pages
20-28
Published: January 01, 2014
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The complication of major depressive disorder and adjustment disorder is frequently seen in patients with cancer. Though appropriate psychosocial intervention is demanded for these disorders, it is often overlooked in a clinical setting. We reviewed the randomized controlled trials regarding the screening intervention program in patients with cancer. Information of preview studies suggests the screening intervention program might contribute to psychosocial health when patient refers to appropriate psychosocial care based on the screening results. In addition, 6 screening tools for major depressive disorder and adjustment disorder are recommended to use in Japanese patient with cancer.
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Tatsuo Akechi
Article type: Article
2014 Volume 54 Issue 1 Pages
29-36
Published: January 01, 2014
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Cancer treatment has tremendously progressed, and hence the development of cancer is not necessarily a death sentence. Nevertheless, approximately half of cancer patients actually die even today. In Japan, cancer has been the leading cause of death since 1981 and is the most common and representative life-threatening disease. Cancer causes profound suffering to patients, and previous studies have reported that psychological distress, particularly depression, is freuently observed in cancer patients. Several studies have indicated that such depression can lead to serious and far-reaching negative consequences in patients with cancer : reducing their quality of life and causing severe suffering, a desire for early death and suicide, as well as psychological distress in family members. These results imply that cancer patients should receive appropriate management and care against their depression during the course of their illness. This review introduces recent evidences with regard to the effectiveness of pharmacotherapy and psychotherapy on depression and depressive disorders among cancer patients.
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Eisuke Matsushima
Article type: Article
2014 Volume 54 Issue 1 Pages
37-44
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In general, delirium is considered a heterogeneous state that can be caused by multiple factors. Delirium is clinically divided into three subtypes ; hyperactive, hypoactive and mixed delirium. It is reported that hypoactive delirium is commonly observed in cancer patients and accounts for half of all cancer cases. Clinical symptoms of hypoactive delirium include lack of awareness, reduced alertness, sparse or slow speech, lethargy. Hypoactive delirium can be overlooked in a clinical setting because the symptoms of this kind of delirium are unremarkable. Moreover, hypoactive delirium is often mistaken for depression. Management to improve organic factors and drug therapy might be necessary for delirium treatment. In terminal delirium, the treatment goal must be set to controlling rather than reversing symptoms.
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Hideki Onishi, Mayumi Ishida
Article type: Article
2014 Volume 54 Issue 1 Pages
45-52
Published: January 01, 2014
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The occurrence of malignant tumors is also a shocking event for patients' families. It forces them to markedly change their daily activities, while psychologically and physically affecting them. Consequent severe distress frequently causes physical and mental problems resulting in difficulty in maintaining daily activities. In this respect, families of cancer patients may be regarded as "second patients" requiring medical services and care. Bereavement, one of the most stressful life events, affects the diverse aspects of bereaved families' mental and physical health ; it increases suicide rate, incidence of depression, and mortality while deteriorating physical disorders. Consequently, for some bereaved family members, it becomes difficult to maintain their daily lives. Support for them has been conceptualized as "postvention". The provision of family and bereavement care is still insufficient. Further clinical practice and studies are needed.
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Shuji Inada, Kazuhiro Yoshiuchi
Article type: Article
2014 Volume 54 Issue 1 Pages
53-58
Published: January 01, 2014
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Since palliative care consultation was covered by National Medical Insurance in 2002, palliative care consultation teams have been established providing specialized palliative care in many hospitals. In order to fulfill the purpose of palliative care which provides continuous care and improvement of the quality of life of patients and families, close attention is essential not only pain but also to other problems such as social and spiritual backgrounds. It is also necessary that palliative care teams collaborate with medical staff such as oncologist, link nurse, physical and occupational therapists, psychologist, medical social workers. With assessments based on the bio-psycho-socio-ethical model and cognitive-behavioral approach, psychosomatic medicine may play an impotant role in the activity of palliative care consultation team.
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Yusuke Miwa, Michio Hosaka, Daisuke Matsushima, Masayu Umemura, Sakiko ...
Article type: Article
2014 Volume 54 Issue 1 Pages
59-66
Published: January 01, 2014
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Objectives : The objective of this study was to investigate the relationships between response to the treatment and activity of daily living (ADL), health-related quality of life (HRQoL) and depression in rheumatoid arthritis (RA) patients treated with biologic agents. Methods : Seventy-five RA patients (infliximab, 36 patients ; etanercept, 15 patients ; adalimumab, 19 patients tocilizumab, 17 patients) were assessed prior to treatment and again 14 weeks after the initiation of therapy. Age, gender, and steroid dosage were obtained for each participant. The disease activity in the patients was evaluated using the disease activity score (DAS) 28. The ADL (modified health assessment questionnaire [mHAQ]), HRQoL questionnaire (Short Form [SF]-36) and the depression scale (Japanese version of the structured interview guide for the Hamilton Depression rating scale [HAM-D] and the Self-rating Depression Scale [SDS]) were evaluated. Based on the EULAR improvement criteria for RA, patients were classified into three groups : good response to treatment (39 patients), moderate response to treatment (24 patients) and no response to treatment (12 patients). Results : After 14 weeks of treatment, scores of the "physical function" and "social functioning" from the SF-36 showed significant improvement among 3 groups, according to the repeated measure ANOVA. Although three groups' interaction was recognized, score of the "body pain", "general health perception" and "energy" from the SF-36 significantly improved in the good response group according to the paired t-test adjusted for the Bonferroni. The score of the mHAQ showed significant improvement among 3 groups, based on the repeated measure ANOVA. Although three groups' interaction was recognized, The scores of SDS and HAM-D significantly improved in the good response group. The score of the "pain" and "general health perception" in the SF-36 and the score of SDS significantly improved, but the scores of "energy" in SF-36 and the HAM-D did not significantly improve in the moderate response group. By contrast, no significant improvement was indicated in all the items in the no response group.Conclusions : Our results show that good treatment-response asa measured by the EULAR response criteria can be translated into improved depression anda HR-QoL dimensions in RA patients.
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Tomoe Nishihara, Shu Takakura, Tomokazu Hata, Hiroaki Yokoyama, Motoha ...
Article type: Article
2014 Volume 54 Issue 1 Pages
67-74
Published: January 01, 2014
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Takotsubo cardiomyopathy (TC) is characterized by transient hypokinesis, akinesis, or dyskinesis in the left ventricular (LV) mid segments with or without apical involvement, provoked by an episode of emotional or physical stress. Recently, TC has been reported to be a severe complication in patients with AN. In this paper, we present two cases of young female AN patients who had suffered from TC. Case 1 : A 18-year-old female patient who had two-year history of AN, was admitted to the emergency room of our hospital. Her body mass index (BMI) was 9.2 kg/m^2. Her blood glucose level was below detection limits. Her electrocardiogram (ECG) showed ST-segment elevation in anterior and lateral leads, accompanied by apical akinesis, a typical finding of "TC" in echocardiography (UCG). Case 2 : A 32-year-old female patient who had two-year history of severe AN, was transferred to our department because of her BMI was 9.0 kg/m^2, and hypoglycemia and hypotension were manifested. She showed inverted T in precardial leads of her ECG, concomitant with severe LV dysfunction in UCG. These two patients were diagnosed as suffering from TC, because their ECG and UCG findings were not correlated with the distribution of a single major coronary artery They failed to show any elevation of blood CK levels during their clinical courses. We recommend routinely performing cardiac evaluation to detect TC in patients with severe AN.
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[in Japanese]
Article type: Article
2014 Volume 54 Issue 1 Pages
75-
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[in Japanese]
Article type: Article
2014 Volume 54 Issue 1 Pages
76-77
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Kazuyoshi Ookuma
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2014 Volume 54 Issue 1 Pages
78-81
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[in Japanese]
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2014 Volume 54 Issue 1 Pages
82-
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Article type: Article
2014 Volume 54 Issue 1 Pages
82-83
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2014 Volume 54 Issue 1 Pages
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Article type: Article
2014 Volume 54 Issue 1 Pages
83-84
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2014 Volume 54 Issue 1 Pages
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2014 Volume 54 Issue 1 Pages
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Article type: Article
2014 Volume 54 Issue 1 Pages
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[in Japanese], [in Japanese], [in Japanese]
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2014 Volume 54 Issue 1 Pages
85-86
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2014 Volume 54 Issue 1 Pages
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Article type: Article
2014 Volume 54 Issue 1 Pages
86-87
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2014 Volume 54 Issue 1 Pages
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Article type: Article
2014 Volume 54 Issue 1 Pages
87-88
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2014 Volume 54 Issue 1 Pages
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Article type: Article
2014 Volume 54 Issue 1 Pages
88-89
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2014 Volume 54 Issue 1 Pages
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
91-94
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
95-97
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
98-101
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
102-103
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
104-106
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
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2014 Volume 54 Issue 1 Pages
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Article type: Appendix
2014 Volume 54 Issue 1 Pages
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Article type: Cover
2014 Volume 54 Issue 1 Pages
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