As tuberculous patients go through various stages of development, their bathing during the treatment is one of the most difficult problems that we clinicians often meet with.
A systematic study has been made on this problem at our Instiute, and in this report the author describes the findings on the problem whether tuberculous patients should or should not bathe in hot springs, obtained from a study on serum cholinesterase activity (Ch-E). Ch-E was determined by Takada-Shibata's method in this study and the subjects for experiments were chosen from tuberculous patients admitted to the National Narugo Hospital. Examinations were made after they were divided into minimal, moderately advanced, and far advanced group, according to the classification of the National Tuberculosis Association of America.
Examination of changes in serum Ch-E values of tuberculous patients and problems concerning hot-spring bathing of tuberculous patients led to the following conclusions:
1) Serum Gh-E values of tuberculous patients are lower than those of healthy persons and they tend to be lower according to the severity of the extent of diseases, especially in the cases of active tuberculosis.
2) A certain degree of parallel relation is observable between serum Ch-E value and the blood sedimentation rate of tuberculous patients.
3) No correlation is found between the serum Ch-E value and serum protein of tuberculous patients, except in some of the far advanced cases of tuberculousis.
4) Observation of changes in serum Ch-E value in tuberculous patients by chemotherapy reveals, that serum Ch-E value will return to the normal value rapidly with improvement of clinical symptoms such as body weight, blood sedimentation rate and negativization of bacilli, etc; and that serum Ch-E values return to the normal value most rapidly. Consequently, serum Ch-E values are conceived to be an indication in the judgment of effects of chemotherapy and of prognosis.
5) Immediately after bathing, serum Ch-E values either rise or fall in healthy adults as well as minimal, and moderately advanced cases, showing individual differences, but they recover their pre-bath values in two hours after bathing. In far advanced cases, and in a part of moderately advanced cases, serum Ch-E values cannot recover their pre-bath values even 2 hours after bathing.
6) Observation of changes in serum Ch-E values before and after single bathing, in the course of curative bathing, reveals that the pronounced changes observed in minimal, and moderately advanced cases in the early stage of curative bathing became gradually less in number until they are no longer observable. That is socalled phenomenon of accommodation and it can be observed by the stimulation of hot-spring bathing.
7) Hot-spring bathing for curative bathing brings about a good effect in clinical symptoms on those patients in whom the accommodation phenomenon is sufficiently apparent, but bad effects are sometimes observable in those, in whom the accommodation phenomenon cannot be observed.
8) It was found from the results described above, that changes in serum Ch-E values are due mainly to non-specific stimulation of hot-spring bathing. Care must be exercised in far advanced cases in which changes are most pronounced, and in which the return to their pre-bath values is slow, especially in those, who have some defects against the appearance of the accommodation phenomenon, consequently against that of accommodation phenomenon in the course of curative bathing. On the other hand, hot-spring bathing two to three times a week does more good than bad for tuberculous patients who show an accommodation phenomenon vis-a-vis any bathing just as the healthy persons.
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