Supramolecular glycopolymers are constructed by non-covalent interaction of carbohydrates monomers, which possess mechanical and self-healing properties based on the cross-linked structure derived from the non-covalent bonds. Naturally occurring cyclodextrins, cellulose, chitin, and chitosan have been used to prepare supramolecular glycopolymers. However, recent advances in synthetic methodologies for sugar molecules have led to research using chemically synthesized sugar derivatives. In this mini review, I describe the influence of chemically synthesized carbohydrates monomers structures on the structures and functions of supramolecular glycopolymers.

Chondroitinase ABC-I (cABC-I) has been studied for many years as an enzyme that degrades chondroitin sulfate (CS). There are several isomers of CS, and the reactivity with cABC-I is also different for each CS isomer. In this paper, we review the substrate specificity of cABC-I based on the results of analyzing cABC-I reactivity to CS that is more homogeneous, and the crystal structure of the cABC-I complex with unsaturated disaccharide derived from CS.

Supramolecular glycopolymers are constructed by non-covalent interaction of carbohydrates monomers, which possess mechanical and self-healing properties based on the cross-linked structure derived from the non-covalent bonds. Naturally occurring cyclodextrins, cellulose, chitin, and chitosan have been used to prepare supramolecular glycopolymers. However, recent advances in synthetic methodologies for sugar molecules have led to research using chemically synthesized sugar derivatives. In this mini review, I describe the influence of chemically synthesized carbohydrates monomers structures on the structures and functions of supramolecular glycopolymers.

Chondroitinase ABC-I (cABC-I) has been studied for many years as an enzyme that degrades chondroitin sulfate (CS). There are several isomers of CS, and the reactivity with cABC-I is also different for each CS isomer. In this paper, we review the substrate specificity of cABC-I based on the results of analyzing cABC-I reactivity to CS that is more homogeneous, and the crystal structure of the cABC-I complex with unsaturated disaccharide derived from CS.