The effect of Bioglass on the amputated vital pulp was studied histopathologically using five male beagle dogs aged 14 months. The amputated pulps were divided into three groups according to their capping materials, i. e, group 1, Bioglass granules; group 2, mixture of Bioglass granules and calcium hydroxide powder; and group 3, calcium hydroxide powder. The pulp tissues and their neighboring hard tissues were examined 10, 20, 30, and 60 days after the vital pulp amputation.
The results were as follows:
1. The morphological healing process of amputated pulp tissues in group 1 and 2 was basically similar to that of group 3.
2. The evaluation of healing process of amputated pulp tissues showed a tendency to be more satisfactory in group. 3, less in group 2 and still less in group 1, but these defferences were not significant.
3. Dentin bridge was formed on the pulp surfaces in each group at the same ratio, but the width of dentin bridges in group 1 was thicker than those in groups 2 and 3.
4. Bioglass granules impacted in pulp tissue were phagocytized by numerous histiocytes, but no injurious effect to pulp tissue was seen in any of the sections.
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