A 4-year-old, castrated male French bulldog, and a 3-year-old, spayed female Shiba Inu presented with fistula at the bilateral metatarsus. Antimicrobials, and anti-inflammatory agents were not effective for either of these cases. Histopathological examinations revealed fibrosis along with neutrophils and mononuclear cells infiltration with vascular dilation and edema at the deep dermis and subcutaneous tissue. Based on these findings, both animals were diagnosed as having focal metatarsal fistulation. Tocopherol nicotinate, 200 mg, twice a day was administered to improveing peripheral circulation, and fistulosis were aparently disappeared. We suspected that ischemic dermatopathy played a role in its etiology.
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