The Japanese Journal of Veterinary Dermatology
Online ISSN : 1881-2236
Print ISSN : 1347-6416
ISSN-L : 1347-6416
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Case Report
  • Long-term management with lokivetmab of canine cutaneous epitheliotropic T-cell lymphoma
    Yuichiro Kawaguchi, Maiko Sekiguchi, Toshiroh Iwasaki
    2025 Volume 31 Issue 2 Pages 89-94
    Published: 2025
    Released on J-STAGE: June 20, 2025
    DOIhttps://doi.org/10.2736/jjvd.31.89
    JOURNAL FREE ACCESS
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    A 13-year-old dachshund diagnosed with cutaneous epitheliotropic T-cell lymphoma showed erythema, scales, and pruritus on the left flank. Lokivetmab was administered at 10 mg, and pruritus disappeared. The treatment was continued every 4 weeks, but pruritus returned and the skin lesions gradually worsened. The dosage was increased to 30 mg/head, and not only pruritus but also the erythema and scales disappeared. Subsequently the dosage was increased by 10 mg, and finally to 50 mg. The patient died of acute pancreatitis 769 days after the start of treatment. Lokivetmab was effective against pruritus and skin lesions in this case, and may have extended the survival time.

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