A 4-year-old female rabbit presented with two nodular lesions on the left side of the abdomen, adjacent to the femoral region. No surgical operation was done because a malignant skin neoplasm with poor prognosis was suspected. The appetite of the rabbit gradually decreased and the rabbit died 41 days after this presentation. The two nodules rapidly increased and fused into a single large oval mass. Histopathologically, round, spindle-shaped and pleomorphic tumor cells were observed. These tumor cells showed atypical nuclei with mitotic figures and some were multinucleated. Immunohistochemical analysis revealed that the tumor cells were positive for vimentin and α-smooth muscle actin, but negative for cytokeratin and desmin. Consequently, this case was diagnosed as cutaneous pleomorphic leiomyosarcoma.

A 1-year-old, spayed female Himalayan cat presented with traumatic alopecia at the flanks, the cauda and the precordia. Palpation induced excessive licking behavior over the trunk. The cat was treated with glucocorticoids, selective serotonin reuptake inhibitors, and a neuropathic pain agent. The lesions improved, but relapsed with cessation of glucocorticoids. Then Demodex gatoi was detected in the scaly alopecia, and oral fluralaner was administered. The alopecia improved and tests for D. gatoi became negative after 2 months. The medications were withdrawn, and the traumatic alopecia relapsed. It was cured by the reintroduction of fluoxetine and pregabalin, as well as administration of fluralaner every 3 months. Finally, no glucocorticoids and fluralaner were required. The relationship between D. gatoi infection and feline hyperesthesia syndrome is discussed.