The Oral Food Challenge test, hereafter called OFC, is spreading throughout the entire country thanks to the publication of recent guidelines (Japanese Pediatric Guideline for Food Allergy 2005, Japanese Pediatric Guideline for Oral Food Challenge test in Food Allergy 2009). However, its main constituents are made up of those participating upon admission to a hospital. We herein report on the method/outcome of 333 OFC performed in 2010 at the outpatient department of our private clinic. The subjects consisted of 333 cases (164 patients: 107 male and 57 female) who underwent OFC from January to October of 2010. The ages ranged from 10 months old to 22 years old. A sufficient explanation was provided to the patients regarding the method, risks, etc., prior to the challenge, and consent was obtained. Single-day, multiple-dose administration was carried out in 30-minute intervals using an open method. The tested food was occupied, in order of: 45.6% to hen's egg, 22.5% to milk, and 11.4% to wheat, making up approximately 80% of all foods. 149 cases (45.4%) were judged as positive, with 95.3% showing skin manifestations, 24.2% showing respiratory symptoms, and 10.7% showing gastrointestinal symptoms. Anaphylaxis was observed in 34 cases (10.2%), and an intramuscular injection of adrenaline was applied in 14 cases (41.2%). Subsequent dietary interventions were conducted depending on the outcome of OFC. It is believed that a safe and reliable OFC can be carried out in the private outpatient clinic as well, by devising a method of OFC and then promptly treating any induced symptoms.

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Objective: Food allergy which infancy suffers from much may cause an emergency visit because of an immediate symptom.
We examined patients who visited the emergency room in our hospital.
Subjects and method: We evaluated symptoms, nurses' triage assessments, and potential treatments for 101 patients who presented with immediate food allergies to our hospital between January 2009 and December 2010.
We also examined 6 patients who were brought in by ambulance to the hospital.
Result: The causal foods were eggs in 40 (39.6%), cow's milk in 17 (16.8%) and fish eggs in 10 (9.9%) patients. According to the triage by the nurse, two patients (1.9%) were 'resuscitation', 28 patients (26.9%) were 'emergency', 36 patients (35.9%) were 'associate emergency' and 17 patients (16.8%) were 'non-emergency'. Adrenaline was administered to 4 patients (4.0%). For the 6 patients who were brought in by ambulance to the hospital, the causal foods were milk (2 patients), eggs (2 patients), and nuts (1 patient).
Conclusion: The major causal foods for immediate allergic symptoms were eggs, milk, and fish eggs. Adrenaline was administered in low doses to the patients. It was thought that we have to share knowledge about initial correspondence include adrenaline injection.

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Objective: We investigate what kind of influence allergic children came under by the Great East Japan earthquake, and examine future correspondence.
Subjective and method: Subjects were caregivers of 402 allergic children who were asked to fill in a questionnaire after informed consent in Department of General Pediatrics, Miyagi Children's Hospital, Department of Pediatrics, National Hospital Organization Sendai Medical Center and Morikawa Pediatric and Allergy Clinic.
Results: The most common troubles of allergic children in the disaster were "Electric inhalation could not be used because of the failure of the electric power supply" for bronchial asthma, "Eczema worsened because they could not take a bath" for atopic dermatitis, and " It was hard to obtain their special foods and milk" for food allergy.
Conclusion: As future correspondence for the great earthquake disaster, we thought that the preparation of inhalant and the inhaler which we can inhale even at the time of blackout for the asthma bronchial, the guidance of the skin care when we cannot take a bath for the atopic dermatitis, and storage of the special foods and milk for food allergy and enlightenment activity to be able to deepen understanding to food allergy in the public organizations such as the refuge for the food allergy.

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The causes of childhood asthma death were analyzed on 206 patients from 0 to 34 years of age, who had died from 1988 to 2010 and were reported to the committee until October in 2010. Subjects analyzed were divided into two groups by year to study the annual change in asthma death; the former group who died between 1988 and 1997 and the latter group between 1998 and 2010.
The number of annual asthma death has decreased since 1998.
Sex ratio (Male to female) was 98 to 63 (1.6 : 1) in the former group and 28 to 17 (1.6 : 1) in the latter group. The grades of asthma severity during one year before asthma death were severe 45%, moderate 30%, mild 26% in the former group and severe 38%, moderate 27%, mild 35% in the latter group respectively showing no differences between the groups.
Number of deaths in the hospital where they had usually visited were 73% in 0 to 6, 55% in 7 to 12 and 38% in older than 13 years of age showing that the older the asthmatic children became, the more the number of asthma deaths in the places other than the hospital increased. There were some cases of asthma death where school environment was concerned. The primary contributory cause for asthma death was unexpectedly rapid exacerbation 94% that was most important and the second cause was delay in time for visiting the hospital 83%. The medication in the most recent one year indicated increases in inhaled corticosteroids from 24% in the former group to 38% in the latter group and also a novel beta-agonist patch was recognized.
Analysis in the medication use before asthma death according to severity revealed that corticosteroid use in both inhaled and oral seemed inadequately less and the analysis for short acting beta agonist inhaler use showed same tendency.
Concerning other medications, numbers of cases reported were so few, clear conclusion seemed difficult to be drawn.

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