Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
Online ISSN : 1882-2738
Print ISSN : 0914-2649
ISSN-L : 0914-2649
Volume 7, Issue 1
Displaying 1-7 of 7 articles from this issue
  • [in Japanese]
    1993 Volume 7 Issue 1 Pages 1-10
    Published: February 25, 1993
    Released on J-STAGE: April 30, 2010
    JOURNAL FREE ACCESS
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  • Kei Masuda, Yoko Miyabayashi, Koichi Yamaguchi, Kan Toyama, Eisaku Iwa ...
    1993 Volume 7 Issue 1 Pages 11-15
    Published: February 25, 1993
    Released on J-STAGE: April 30, 2010
    JOURNAL FREE ACCESS
    Atopic cataract is one of the most serious ocular complications in the patient with atopic dermatitis, and occurs mostly in adolescent period.
    We experienced 3 cases of atopic cataracts with atopic dermatitis. There were several common factors, i. e. (1) severe atopic dermatitis (2) asthma (3) high serum IgE level (4) positive RAST or skin test to house dust, mite, candida etc. Some of these factors may lead to the exacerbation of atopic cataract.
    Prevention of atopic cataract is the most urgent problem in the management of atopic dermatitis. Atopic cataract is exacerbated commonly in adolescent period. Therefore in this period, we should diagnose cataract in early stage by ophthalmological examination, and adequate treatment of atopic dermatitis may result in prevention of atopic cataract.
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  • REPORT OF 2 CASES AND EXPERIMENTAL STUDIES ON ABSORBANCE CAPACITY OF ACTIVATED CHARCOAL
    Kiyohiko Ooshiro, Kunio Ichikawa, Eisaku Iwasaki, Minoru Baba
    1993 Volume 7 Issue 1 Pages 16-22
    Published: February 25, 1993
    Released on J-STAGE: April 30, 2010
    JOURNAL FREE ACCESS
    We roported two cases of theophylline intoxication in which activated charcoal was given as treatment, and we experimentally evaluated the theophylline absorbability of activated charcoal.
    Case 1: A 4 years and 6 months old boy had been given both of continuous intravenous infusion of aminophylline and oral sustained-release theophylline formulation by medication error. He had tremor and the peak serum theophylline level was 35.68μg/ml. Then he was given 0.5g/kg of activated charcoal orally. The elimination rate constant (Kel) was 0.158/h in the first 2.5 hours after the charcoal administration.
    Case 2: A 12 years and 6 months old girl took sustained-release theophylline formulation and felt discomfort after last medication. Serum theophylline level was 28.79μg/ml at 2.5 hours after the medication and the patient was given 0.5g/kg of activated charcoal orally. The elimination rate constant in the first 110 minutes was 0.148/h.
    In in vitro study, 7.4g of activated charcoal could absorb 1g of theophylline. Theophylline was absorbed immediately after the addition of activated charcoal. The amount of theophylline absorbed was the highest at pH5.
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  • Takashi Yamada, Kazuhiro Sasamoto, Hironori Nakamura, Megumi Yamada, T ...
    1993 Volume 7 Issue 1 Pages 23-27
    Published: February 25, 1993
    Released on J-STAGE: April 30, 2010
    JOURNAL FREE ACCESS
    We treated a girl with bronchial ashtma who was diagnosed food-dependent exercise-induced anaphylaxis due to fish. She developed anapylaxis by exercise from 30 to 60 minutes after having several kinds of fish. We found positive reactions to several kinds of fish by skin test and by specific IgE antibodies. We did not performe exercise inducement after having fish because anaphylactic reaction will strongly be induced. We didn't observe anaphylactic reaction after exercise task without food challenge. We found her symptom dramatically inproved after elimination of fish.
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  • Yuhei Hamasaki, Ikuko Kobayashi, Shigetaka Matsumoto, Tomohiro Ichimar ...
    1993 Volume 7 Issue 1 Pages 28-33
    Published: February 25, 1993
    Released on J-STAGE: April 30, 2010
    JOURNAL FREE ACCESS
    Relaxing action of VIP on acethylcholine (Ach)-induced pre-contraction of smooth muscle of isolated guineapig trachea was examined in a condition with or without epithelium. The action was compared with those of isoproterenol and theophyline. Dose-response curve produced by Ach was also made after VIP (10-8M) was added into a organ bath before applying Ach.
    (1) VIP relaxed Ach-induced pre-contraction of guinea-pig trachea in a dose dependent manner. The action was more potent than those of theophylline and isoproterenol in molar basis.
    (2) Relaxing action of VIP, theophylline and isoproterenol on Ach-induced pre-contraction of the tracheal strip was attenuated by removing epithelium, indicating spontaneous synthesis of epithelium derived relaxing factor in the epithelial cells.
    (3) Inhibitory action of VIP against Ach-induced contraction of the guineapig trachea was not apparent, when VIP was added in the organ bath prior to Ach. This result indicated that VIP might be inactivated by neutral endopeptidase which was produced in epithelial cells after a certain period of time.
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  • A STUDY BY QUESTIONNAIRE
    Masaru Kishida, [in Japanese], [in Japanese], [in Japanese], [in Japan ...
    1993 Volume 7 Issue 1 Pages 34-38
    Published: February 25, 1993
    Released on J-STAGE: April 30, 2010
    JOURNAL FREE ACCESS
    We obtained information through a questionnaire on atopic disease of 1049 children, who visited 24 nursery schools in Shimane prefecture. About 36% of all children had one or more atopic diseases, two third of which was atopic dermatitis and the other was bronchial asthma.
    In contrast with bronchial asthma, infants who were fed with human milk for at least up to 4 months developed atopic dermatitis more than ones with com's milk formula.
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  • EARLY DIAGNOSIS OF FOOD ALLERGY AND PREDICTION OF BRONCHIAL ASTHMA
    F. Horiba, A. Urisu, E. Wada, Y. Kondo, M. Tsuruta, T. Yasaki, S. Masu ...
    1993 Volume 7 Issue 1 Pages 39-44
    Published: February 25, 1993
    Released on J-STAGE: April 30, 2010
    JOURNAL FREE ACCESS
    The aim of this study was to determine the criteria for the selection of subjects who should be tested specific IgE antibodies in early infancy. Specific IgE antibodies for egg white, cow's milk, rice, soy bean and Dermatophagoides pteronyssinus were examined for 255 infants (less than 6 months of age) by means of Phadebas RAST kit. Infants in which at least one RAST item was positive (more than RAST score 2) were judged RAST-positive.
    Infants, aged more than 4 months, with eczema and/or allergic family background should be selected as subjects for the screening test by the RAST. The RAST items for the test were egg white and cow's milk. Infants with RAST-positive results had higher risk for the development of bronchial asthma. Eczema of infants with RAST-positive results was prone to be chronic. These results suggested that the screening test of specific IgE antibodies for egg white and cow's milk in early infancy was effective for the early diagnosis of food allergy and the prediction of bronchial asthma.
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