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Volume 8 (1994)
- Issue 4 Pages 148-
- Issue 3 Pages 97-
- Issue 2 Pages 52-
- Issue 1 Pages 1-
Volume 8, Issue 1
Displaying 1-7 of 7 articles from this issue
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[in Japanese]1994 Volume 8 Issue 1 Pages 1-12
Published: February 25, 1994
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSDownload PDF (1387K) -
Mani Miyoshi, Soichi Kodama, Hajime Nakamura1994 Volume 8 Issue 1 Pages 13-17
Published: February 25, 1994
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSTo evaluate the relationship between serum eosinophil cationic protein (ECP) levels and asthmatic prognosis, we measured serum ECP levels in 39 asthmatic children when they had not asthma attacks, and observed them for two years. Serum ECP levels were higher in the patients who had not improved after two years than those who had. It is suggested that the measurement of serum ECP levels may be useful to predict the prognosis of asthmatic children.View full abstractDownload PDF (595K) -
Satoshi Kikuchi, Komei Ito, Yoshiki Hayashi, Masanori Yamada, Shinpei ...1994 Volume 8 Issue 1 Pages 18-26
Published: February 25, 1994
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSWe have investigated the effect of supplementing the diet with a health food Ipaole, which is rich in n-3 polyunsaturated fatty acids such as α-linolenic, eicosapentaenoic and docosahexaenoic acids, in the patients with atopic dermatitis. Forteen patients including 8 girls and 6 boys (mean age, 9.5 years; range 4 to 14 years), were given Ipaole for at least 4 weeks before evaluation. The supplementation led to a moderate improvement in cutaneous erythema, itch and overall subjective assessment of severity in six of them, and to the mild improvement in two. However, one patient got worse after treatment. No significant change was observed in the other subjects. The plasma phospholipids eicosapentaenoic acid/arachidonic acid ratio (EPA/AA ratio) was greater than 0.5 in the subjects with clinical improvement, while it differs among the individuals. In conclusion, dietary supplementation with the n-3 polyunsaturated fatty acids may be useful for the treatment of atopic dermatitis in children.View full abstractDownload PDF (4151K) -
Toshikazu Tsubaki, Yuzo Sugihara, Ayami Iwasaki, Tatsuro Koshibu, Shui ...1994 Volume 8 Issue 1 Pages 27-34
Published: February 25, 1994
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSIn this study blood levels of theophylline were measured by using simple apparatus, Biotrack, Vision, and TDX. Studies were carried out on 55 patients with bronchial asthma (41 malesand 14 females with a mean age of 8.5±3.6 years) who were attending the Department of Allergy of National Children' s Hospital, performing a total of 99 sessions of blood theophylline mesurement. Blood was sampled when the patients visited the outpatient clinic, and blood levels of theophylline were measured by using three kinds of apparatus, Biotrack, Vision, and TDX. The masurements obtained by the three methods were analyzed for correlation between the three apparatus so as to determine the clinical utility of Biotrack. There was a significant correlation (r=0.978) between Biotrack and Vision (p<0.01), and there was again a significant correlation between Biotrack and TDX (r=0.977) (p<0.01). Based on the results presented it may be concluded that Biotrack favorably compares with other conventional apparatus for mesurement of theophylline in the blood. Furthermore, considering the fast results and high procedural simplicity, Biotrack seems to be a blood theophylline measurement apparatus of clinical use.View full abstractDownload PDF (1847K) -
REDUCTION OF SERUM ANTI HOUSE DUST IGE ANTIBODY DURING DSCG INHALATION THERAPY IN ASTHMATIC CHILDRENNorihide Murayama, Satoru Doi, Toshishige Inoue, Isamu Takamatsu, Mako ...1994 Volume 8 Issue 1 Pages 35-41
Published: February 25, 1994
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSWe examined serum IgE (RIST), house dust specific IgE (RAST) and mite (dermato-phagoides farinae) specific IgE (RAST) in 134 atopic ashtmatic children at the initiation of therapy and one year later. According to their age, they were divided into two groups (<7 years old group and ≥7years old group). Moreover, according to the modality, each group was divided into three groups (DSCG-, theophylline RTC-and no drug group). In theophylline RTC group of <7 years old- and ≥7 years old asthmatic children, IgE (RIST) was reduced significantly. There has been no report that theophylline can reduce IgE production. In DSCG group of ≥7 years old asthmatic children, house dust specific serum IgE (RAST) was reduced from 8.83PRU/ml to 7.49PRU/ml (p<0.05). In other groups, house dust specific IgE (RAST) was not reduced. Kimata et al reported recently that DSCG reduced IgE production in vitro. Our report is the first that DSCG and theophylline are able to reduce IgE production in vivo.View full abstractDownload PDF (730K) -
Yoshihito Takahashi, Kazuo Sugimoto, Hiroki Abe1994 Volume 8 Issue 1 Pages 42-47
Published: February 25, 1994
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSIn order to evaluate rapid injection immunotherapy with house dust (HD) antigen in 27 asthmatic children, we examined the change of levels in serum total IgE, anti-HD IgE antibodies and anti-mite IgE antibodies over 1 to 15 years. The results were as follows:
1) There was no remarkable changes in total IgE levels.
2) Anti-HD IgE and anti-mite IgE antibodies tend to decrease within our researching periods.
3) Rapid injection immunotherapy was thought to be effective in 74.1%, based on asthmatic attack scores or therapeutic scores.
4) No severe side effects were recognized in all cases.
The rapid injection immunotherapy was effective in most of the asthmatic children. It could be one of the major therapeutic choices in the long-term management of bronchial asthma.View full abstractDownload PDF (621K) -
Shinji Shibutani1994 Volume 8 Issue 1 Pages 48-51
Published: February 25, 1994
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSTo investigate the effect of classical music on bronchial hyperresponsiveness, 15 children with severe atopic asthma were studied using an Astograph to measure their bronchial responsiveness. There was no difference in St values between the two groups, but the Dmin values for the group who listened to the music were significantly higher than for those who did not (p<0.05).
This means that bronchial sensitivity was lower among those who listened to music than those who did not. This result suggests that music suppresses bronchial hyperresponsiveness.View full abstractDownload PDF (688K)
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