The effects of the depth of ether anesthesia for surface-induced hypothermia on hemodynamics and blood gas were experimentally studied in the adult Beagle dogs. The dogs were classified into 3 groups according to the depth of ether anesthesia; group I (middle), group II (deep), and group III (light) . Severe arrhythmia was found in groups II and III, and 6 dogs (66.7%) of group II died of ventricular fibrillation or standstill. During hypothermia, hemodynamic changes of groups I and III were significantly milder than those of group II. Aortic mean pressure of group I was maintained higher than that of group III, and the difference was especially significant at the esophageal temperature of 20°C (
p<0.01) . From these results, the ether anesthesia in group I seemed to be superior to that of other groups. Under this level of ether anesthesia, the mean blood ether concentration was 153 mg/d
l at the esophageal temperature of 20°C. Moreover, because a good correlation was noted between blood pH or BE and blood ether concentration, it seemed that they were better indicators of the depth of ether anesthesia.
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