To evaluate the clinical usefulness of end-tidal carbon dioxide (EtCO
2) monitoring, 69 dogs receiving various surgeries or endoscopy were anesthetized with nitrous oxide-oxygen-isoflurane (GOT, n=35) or-sevoflurane (GOS, n=34) under spontaneous ventilation, among which about a half of cases (18 in GOI, 16 in GOS) were subjected to EtCO
2 monitoring. In these cases, the inhaled concentration of anesthetic agents was adjusted to give adequate surgical anesthesia and to maintain the EtCO
2 below 40 mmHg. Anesthetic concentration of the remaining dogs were adjusted without EtCO
2 monitoring according to the anesthetic level of the patient. The anesthetic condition was adequate in the dogs subjected to EtCO
2 monitoring. Respiratory acidosis and a fall in body temperature and peripheral arterial blood pressure were comparatively severe in the dogs without EtCO
2 monitoring, particularly those anesthetized for more than 2 hr. Therefore, EtCO
2 monitoring is useful for safer anesthesia in dogs.
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