Computed Tomography (CT)-guided percutaneous core needle biopsies were undertaken for the diagnosis of osteosarcoma in the pelvis (case 1) and myeloma (case 2) in the seventh lumber vertebra which were difficult to targeted by palpation, ultrasound or fluoroscopy. In both cases, enough tissue for pathological diagnosis were obtained without any complication. CT-guided biopsy was thought to be a safe, easy and effective technique for the evaluation of the deep seated bone lesion.

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A left renal neoplasm found during a physical examination of a 14-year-old male Shih-Tzue prior to vaccination was surgically removed and histopathlogically diagnosed as renal cell carcinoma. Eight months later, mass lesions were detected in lung and skin. A cutaneous lesion was surgically removed and histopathologically diagnosed as metastasis of the renal cell carcinoma. The pulmonary lesion grew slowly thereafter, whereas the recurrent masses grew rapidly in the abdominal cavity or inguinal area and were surgically excised at 11, 16, and 20 months after the first operation. In combination with these surgeries, chemotherapies using adriamycin, carboplatin, and piroxicam were also performed. A small recurrent lesion disappeared after carboplatin administration. The dog maintained good physical condition without severe side effects from the chemotherapies, but died in a traffic accident 22 months after the first operation

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