馬ニ於ケル撓骨神經ノ分布領域ハ腕關節以下ニ於テ全ク不明ナリ成書ニ據ルモ該神經ノ末梢ニ關スル記載ナシ余等ハ犬ニ於テ前肢ノ知覺神經ヲ截斷セル場合其ノ領域ニ於ケル創傷ノ治癒機ヲ研究中偶々知覺神經ヲ截斷スル時ハ肢ノ先端ニ充血浮腫次デ壞疽ノ起ルヲ發見セリ而シテ此事實ハ犬ニ於テ前肢ノ知覺神經ノ總テ即チ正中神經尺骨神經及ピ撓骨神經ヲ截斷セル場合ニノミ起リ其ノ一或ハ二ヲ殘ス時ハ多少ノ充血現ハルルノミニ止マルモノナルコトヲ知レリ又一方ニ於テ馬ノ前肢ニ重複截神術即チ正中及ピ尺骨神經ノ截斷ヲ行フ時ハ蹄温ノ上昇ヲ來スコトハ從來人ノ知ル所ナリ尚時トシテ脱蹄ヲ生ズルコトアルコトモ衆知ノ事實ナリ
以上ノ事實ヨリシテ馬ニ於テ若シ正中及ピ尺骨神經ノ外ニ撓骨神經ヲモ截斷セバ蹄ニ起ル變化ハ單ニ重複截神術ヲ行ヒタル場合ヨリモ一層著明ナル可シト相像セラル可シ然レドモ解別學上撓骨神經ヲ其ノ上部ニ於テ手術スルコトハ甚ダ困難ナルガ故余等ハ恐ラク此ノ神經ガ蹄ニ迄分布セルモノト相像シ球節ノ直上ニ於テ皮膚ヲ約3cm.ノ幅ニ帶状ニ管部ヲ繞リテ皮下結締織ト共ニ截除シ管骨伸腱及屈腱ヲ露出セシメタリ此ノ手術ガ果シテ肉眼ニ見エザル撓骨神經纎維ノ連續ヲ中斷セルヤ否ヤヲ檢センガ爲先ヅ以テ正中及ピ尺骨神經ヲ截斷シテ蹄温ヲ測定シ然ル後ニ本手術ヲ行ヘリ
正中及ピ尺骨ノ2神經ノミヲ截斷スル時ハ該肢ノ蹄温ハ健肢ノ蹄温ニ比シ僅ニ1°-2°C上昇セルノミナルモ上記ノ如ク此等2神經ノ截斷ニ加フルニ球節直上ニ於テ皮膚ノ剥離術ヲ行フ時ハ手術肢ノ蹄温ハ健側ノ蹄ニ比シ10°C以上上昇セリ
實驗例僅少ナル故的確ナル結論ヲ掲ゲ能ハザルモ以上ノ結果ヨリシテ撓骨神經ハ馬ニ於テモ小動物ト同樣ニ肢端即チ蹄ニ迄分布セルモノト考フルモ誤少ナカルベシト信ズ

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As already reported by many workers, some normal rabbit serum has a non-specific property to fix complement in a certain degree, when several kinds of antigen, viz. bacterial or lipoidal, are used. This effect can be demonstrated by using the antigens or the specific sera in which the haemolytic and anticomplementary action was determined not to be present. For this reason it may be apparently quite impossible to distinguish this effect from the specific fixation of complement. Based upon this fact it is generally indicated that in the conduction of specific complement fixation the rabbit might not be used, because this animal is not suitable for the close study of specific amboceptors. Regarding this problem, Schilling and Haesslin recognized this phenomenon first in 1908 by using normal rabbit serum which showed an apparent specific reaction with an alcoholic syphilitic liver extract antigen. In 1916, Kolmer and Trist found also that the similar reaction took place, caused by the normal rabbit serum when several kinds of bacterial antigens have been employed and, moreover, the phenomenon appeared more markedly as compared with the cases in which lipoidal antigens were employed. Besides these observers, Manteufel and Waithe, Browning and Mc Kengie came to the same result in their works with experimental trypanosomiasis; Dohi, Haeberstaedter, Blumenthal, Prausnitzs and Stern, Emmanuel, Epstein and Pribraum, Kolmer and Casselman, Trist and Kolmer also in the use of other lipoid antigens; Kritchewsky, Helleus, Huddlesson, Kaneko and others in the employment of several bacterial antigens. However, as observed by these authors the non-specific fixation affected with normal rabbit serum in the presence of several kinds of antigens does not appear in a constant effect and its manifestation varies with the individuality of rabbit used or the nature of antigens; furthermore, this phenomenon generally appears more remarkably in the use of inactive serum than in the employment of active serum, even when the serum is taken from one and the same rabbit. With regard to the intensity of the non-specific reaction, Kolmer and Pearce concluded that, working with the blood serum taken from one and the same rabbit for a long time, there is no evidence of any change in the reaction. On the other hand, Kaneko stated that in the case of using serum from a positively reacted rabbit, the amount of complement to be fixed was almost constant, but in some cases showed variability, and, on the contrary, with the negative serum, it was quite impossible to demonstrate any measurable change in the reaction. Concerning the elimination of such effect, Emmanuel proposed that the injection of salvarsan might be temporarily efficient for this purpose, while Epstein and Pribraum insisted that the same result could be obtained by the injection of mercurials. And Sachs and Georgi also described that the effect above mentioned could be eliminated by the removal of serum globulin by employing N/250 hydrochloric acid solution. Kolmer expressed later that though the mechanism through which this phenomenon takes place is not yet perfectly demonstrated, this effect can be acted by some elements which must be contained in both lipoid substance and the serum protein. And from his experiment with regard to their property, he stated that the capacity of the elements to fix complement will be remarkably enhanced by heating the serum at 56°C for half an hour, while it will be abated by treating at 62°C for the same length of time; and it will be lost completely by heating at 70°C for thirty minutes.
In our complement fixation tests with regard to the contagious pleuro-pneumonia in cattle, we also experienced that most of the normal rabbit serum showed the effect to fix complement reaction with the specific antigens, just as it was observed in other systems by several authors.

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鷄ノミナラズ多クノ鳥類ニ於テ其ノBursa Fabricii,輸卵管及卵内ニ於テProsthogonimusノ數種ガ見出サレテイル日本ニ於テ鷄卵内ニ見出サレタ日本鷄卵吸虫Prosthogonimus japonicusニ就イテ妹尾,小林氏等ノ記載ガアルノミデアルProsthogonimusノ發育史ニ關シテハ近年ニ至リ獨ノSzidat⁽⁴⁾米ノKotlan及Chandler⁽⁶⁾3氏ガ相次デProsthogonimus intercalandusナル同一種ニ就テ研究シとんぼ及やんまノ數種が其ノ中間宿主ナルコトヲ確メタ
奉天附近ニ於ケルとんぼ及やんまヲ檢スルニとんぼニ於テハ3種300餘匹中末ダ此種ニ屬スル被嚢幼虫ヲ發見シ得ナイガ唯ぎんやんまニ於イテノミ被檢100餘匹中30匹餘ノ幼虫體ヲ發見シ雄雛ニ餘食セシメテ其ノBursa Fabricii中ニ10匹ノ生虫體ノ寄生スルヲ確メ得タルノデアル
此ノ所謂鷄卵吸虫ハ日本鷄卵吸虫トハ異リSkriabinガ露領とるきすたんノ一地ニ於テへらさぎノBursa Fabricii中ニ發見シProsthogonimus putschkowskiiト命名セルモノト同一種デアル
北歐及北米ノ池畔地方ニ於イテProsthogonimusハ時ニ雌鷄ヲ犯シ其ノ輸卵管ニ寄生シ鷄卵内ニ小血塊及虫卵ヲ混入セシメ又稀ニハ虫體自身之ニ侵入シ更ニ病勢ノ進ム時ハ遂ニ鷄ノ産卵ヲ不可能ナラシムト云ハル此吸虫ノ自然界ニ於ケル種ノ保存ハ主ニ水禽ニヨツテ行ハレテイルト思フ南滿洲ニ於ケル本虫ノ家鷄感染ノ實例ニ就イテハ末ダ正確ニ知リ得ナイノデアルガへらさぎ其他ノ水禽ヲ本宿主トスル本虫ガぎんやんまヲ中間宿主トシテ時ニ家鷄ヲ犯ス機會ニ遭遇スルモノノ如ク考ヘラレル
雌鷄ニ於ケル實驗ニ就イテハ第2報トシテ報告シタイト思フ

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Biazzoノ發表シタル銅定量法ニ基キ,尿及心臟,肝臟若クハ血液ノ如キ生體組織ノ含有スル銅ヲ定量スル法ヲ研究シ,更ラニ之ヲ改良シテ生化學的研究ニ當リ,克ク銅ノ微量比色定量法トシテ應用セラルベキヲ證明セリ

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