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井勝 久喜, 篠田 純男
1998 年 44 巻 1 号 p.
1-16
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
The environmental pollution by hazardous chemicals has been concerned. The discharge of hazardous chemicals into the environment must be prevented since it is difficult to specify the environmental influence by the chemicals. From the viewpoint of the health protection for employees, the handling of a lot of chemicals is regulated by various laws. However, the discharge of chemicals is hardly regulated. The chemicals on which the effluent standard has been already determined are only limited to a part of chemicals used in the laboratory. Even if the chemicals where the effluent standard is not set, the discharge of harmful chemicals must be avoided. In order to prevent the environmental pollution by chemicals, researchers themselves must learn how to manage the handling of used chemicals. Laboratories are, therefore, required to reduce the amounts of chemicals used and chemical wastes discharged. The chemicals should be used safely in the laboratory, in consideration of the environmental conservation and public health. Separate collection of chemical wastes at the generation source is the most important means for the safe treatment of the wastes. The basic principle of the treatment is to treat the wastes properly at the generation source. It is important for the original dischargers to recognize their responsibility as generators of the wastes.
抄録全体を表示
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丸山 節子
1998 年 44 巻 1 号 p.
17-24
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
In Nagano Prefecture, in the period of January to March, 1997, sudden deaths of Bombycilla spp. birds happened in many places, amounting to 13 places with the total death of 187 birds. Of the places, Shimosuwa Town, Komoro City, and Iida City were selected to be inquired into the cause of the sudden deaths. In the case of Shimosuwa Town, the esophagus was choked with nuts of Pyracantha, and cyanide was detected in the content from the esophagus at 10.0 μg/g (average) and in the content from the stomach at 17.0 μg/g (average), suggesting that cyanide or nitrile glycoside would be one of the causes of the deaths. In the case of Komoro City, EPN, an organophosphorus pesticide, was detected from the content in the stomach at 5960 μg/g (average) and from the liver at 11.4 μg/g (average), suggesting that EPN would be a many cause of the death. In the case of Iida City no cause of the death has been known.
抄録全体を表示
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小林 規矩夫, 平山 けい子, 飛田 修作
1998 年 44 巻 1 号 p.
25-33
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
We used intact cells and cell extracts to investigate the metabolic pathway of benzoic acid (BA) in Acinetobacter sp. strain ST-1, which dehalogenates 4-chlorobenzoic acid (4-CBA) hydrolytically and then mineralizes it via the β-ketoadipate pathway. Strain ST-1 degraded BA easily, yielding cis, cis-muconic acid and β-ketoadipic acid. A cell extract prepared from cells grown with BA transformed catechol into cis, cis-muconic acid and β-ketoadipic acid, but an extract of cells grown on 4-CBA lacked catechol 1, 2-dioxygenase activity. These results show that BA and 4-CBA are degraded in strain ST-1 by different pathways up to a common intermediate, β-ketoadipic acid, and that BA induces catechol 1, 2-dioxygenase. Therefore, the strain degraded BA via catechol to cis, cis-muconic acid and then to β-ketoadipic acid. The degradation pathways of BA and 4-CBA in strain ST-1 may be linked by the formation of β-ketoadipic acid, and then proceed along the β-ketoadipate pathway, even although the key intermediates before the ring fission are different, namely, catechol for BA and protocatechuic acid for 4-CBA.
抄録全体を表示
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笠井 映江, 北村 剛志, 高橋 優子, 門藤 淳代, 平山 晃久, 渡辺 徹志
1998 年 44 巻 1 号 p.
34-41
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
The genotoxicity of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) was assayed by the wing spot test for detecting somatic cell mutations and the DNA-repair test for detecting DNA damage with Drosophila melanogaster. Although PhIP increased the frequency of small single spots in a dose-dependent manner in the wing spot test, no large single spots and twin spots were induced to a significant extent. In the DNA-repair test PhIP showed clear DNA-damaging activity. The DNA-damaging potency of PhIP was significantly increased when larvae were pretreated with β-naphthoflavone (BNF) 24-48 h after oviposition. Excessive reduction of the Rec
- male/Rec
+ female ratio was also observed in ethanol-pretreated stock compared with stock not pretreated. These results indicate that alcohol and BNF, both enzyme inducers, enhance the in vivo DNA-damaging activity of PhIP.
抄録全体を表示
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森 謙一郎, 中村 義昭, 大貫 奈穂美, 横山 敏郎, 小田 陽子, 藤井 孝
1998 年 44 巻 1 号 p.
42-48
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
According to the official analytical method of methanol in commercial aerosol products, the concentration of methanol in their propelled solution was limited to less than 5%. The propelled solution was sampled by propelling aerosol into a flask for the evacuation of the propellant only. There was the possibility of occurrence of errors due to flying nebulized methanol in the procedure of propelling, or due to the high volume of dissolving propellant in the propelled solution. In this paper, after making some test aerosol products, the possibility of occurrence of error was discussed. The recoveries of methanol in the test aerosol products containing the ratio of 5% methanol/ethanol solution and isobutane by weight of 5 : 5, 4 : 6, 3 : 7 were high yields ranging from 97.5 to 99.2%. But those of 2 : 8 and 1 : 9 were 94.4% and 80.3% respectively due to the flying nebulized methanol. The detective yield of methanol in the propelled solution from the test aerosol products in the ratio of 3 : 7, after weighing the propelled solution by pouring it into a volumetric flask, with the propellant kept inside, was only 67.3%. The problem of dissolving propellant was solved by freeing the propellant while swinging the propelled solution flask on a water bath (20°C) within a tiny zeolite and weighing the propelled solution using a 1 mm i. d. tip dropping pipet. As a result of this experiment, it is suggested that the determination of methanol by the official analytical method may not be achieved in an aerosol containing high percentage of propellant.
抄録全体を表示
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伊永 隆史, 楊 屹, 柴田 健介, 本仲 純子, 池田 早苗
1998 年 44 巻 1 号 p.
49-53
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
Sulfate ion in environmental water was determined by flow injection analysis using barium-dimethylsulfonazo-III complex as the reagent at a rate of 12 samples per hour. The linearity and sensitivity were investigated using ethanol-or dimethyl sulfoxide (DMSO)-water as solvent, respectively. DMSO-water medium was beneficial in the determination of a low concentration of sulfate below 3 mg l
-1. The calibration curve was linear in the range of 0.1-7 mg l
-1 with the correlation coefficient of 0.999. The detection limit was 0.1 mg l
-1. The relative standard deviation for 10 injections of SO
42- (5 mg l
-1) was 1.8%. The results of actual sample analysis agreed satisfactorily with those obtained by ion chromatography.
抄録全体を表示
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Takafumi KATOH, Takao OHYASHIKI
1998 年 44 巻 1 号 p.
P1
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Norio MUTO, Rie EGUCHI, Yukie AKAGI, Norio ITOH, Keiichi TANAKA
1998 年 44 巻 1 号 p.
P2
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Yoshito KUMAGAI, Hiromi NAKAJIMA, Kazumi MIDORIKAWA, Shino HOMMA TAKED ...
1998 年 44 巻 1 号 p.
P3
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Satoshi WATANABE, Tetsuya FUKUI
1998 年 44 巻 1 号 p.
P4
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Akira HIRATSUKA, Hidefumi YAMANE, Shinji YAMAZAKI, Naoki OZAWA, Tadash ...
1998 年 44 巻 1 号 p.
P5
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Koichi KATO, Kenzo YAMANAKA, Akira HASEGAWA, Shoji OKADA
1998 年 44 巻 1 号 p.
P6
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Toshikazu KAISE, Teruaki SAKURAI, Tohru SAITOH, Chiyo MATSUBARA, Tetsu ...
1998 年 44 巻 1 号 p.
P7
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Hitoshi UENO, Koji OISHI, Yasuyoshi SAYATO, Katsuhiko NAKAMURO
1998 年 44 巻 1 号 p.
P8
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Shigetada KOZAI, Sumiyo FUCHIMOTO, Yuka FUJITA, Hisao MATSUMOTO
1998 年 44 巻 1 号 p.
P9
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Yasuji HOJO, Tomoko KOBAYASHI, Yoko SHIGEMITSU, Tomoko TANABE
1998 年 44 巻 1 号 p.
P10
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Masaki WATANABE, Tetsuya MURAKAMI, Masakatsu TEZUKA
1998 年 44 巻 1 号 p.
P11
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Tatsumi ADACHI, Kimiko HIRAYAMA
1998 年 44 巻 1 号 p.
P12
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Yasuhiro ISHIBASHI, Koji ARIZONO
1998 年 44 巻 1 号 p.
P13
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Atsuko ADACHI, Chiho IKEDA, Sokichi TAKAGI, Norie FUKAO, Emi YOSHII, T ...
1998 年 44 巻 1 号 p.
P14
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Masako KIYONO, Yoshio UNO, Hidemitsu PANHOU
1998 年 44 巻 1 号 p.
P15
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Hideaki KITO, Hisamitsu NAGASE, Takahiko SATO, Naoki IMAI, Chie SUGIUR ...
1998 年 44 巻 1 号 p.
P16
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Naomi KUDO, Naoki BANDAI, Yoichi KAWASHIMA
1998 年 44 巻 1 号 p.
P17
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Motoyasu OHSAWA, Kazuko TAKAHASHI
1998 年 44 巻 1 号 p.
P18
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Takumi ISHIDA, Megumu HATSUMURA, Kenji TASAKI, Ayako FUKUDA, Yuko YOSH ...
1998 年 44 巻 1 号 p.
P19
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Koichi HARAGUCHI, Yoshihisa KATO, Ryohei KIMURA, Yoshito MASUDA
1998 年 44 巻 1 号 p.
P20
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Kohji TODOROKI, Shigeki SHIMBA, Masakatsu TEZUKA
1998 年 44 巻 1 号 p.
P21
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Masamichi FUKUOKA, Yoshiaki MATSUMOTO, Zhe HUANG, Tetsu KOBAYASHI, Tak ...
1998 年 44 巻 1 号 p.
P22
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Naohide KINAE, Tatsuyuki TANISHO, Nozomi IMAMURA, Michiyo FURUGORI, Ka ...
1998 年 44 巻 1 号 p.
P23
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Tetsushi WATANABE, Terue KASAI, Shunjiro OGAWA, Teruhisa HIRAYAMA
1998 年 44 巻 1 号 p.
P24
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Tomoaki TSUTSUMI, Satoshi NAGATA, Fuyuko YOSHIDA, Yoshio UENO
1998 年 44 巻 1 号 p.
P25
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Kimiko HIRAYAMA, Akira YASUTAKE, Nobuko MORI, Minoru INOUYE, Shizu HAY ...
1998 年 44 巻 1 号 p.
P26
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Shino HOMMATAKEDA, Yasuhiro TAKENAKA, Yutaka KUGENUMA, ZhongQiang LIAO ...
1998 年 44 巻 1 号 p.
P27
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Chika YAMAMOTO, Toshiyuki KAJI, Syoichi YAMAGISHI, Hiroshi YAMAMOTO
1998 年 44 巻 1 号 p.
P28
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Izumi SADAKATA, Yasumitsu OGRA, Kazuo T. SUZUKI
1998 年 44 巻 1 号 p.
P29
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Toshiyuki KAJI, Akiko MIYAMOTO, Sawako MIYAJIMA, Chika YAMAMOTO, Yasuy ...
1998 年 44 巻 1 号 p.
P30
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Hiroki OKUMURA, Naoto YOSHINO, Tomomi IHARA, Masao SUGAMATA, Ken TAKED ...
1998 年 44 巻 1 号 p.
P31
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Junichi NISHIKAWA, Jun GOTO, Koichi SAITO, Masatoshi MATSUO, Tsutomu N ...
1998 年 44 巻 1 号 p.
P32
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
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Noriyuki USAMI, Kazuhito WATANABE, Ikuo YAMAMOTO, Hidetoshi YOSHIMURA
1998 年 44 巻 1 号 p.
P33
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Yuichi MIYABARA, Hirohisa TAKANO, Takamichi ICHINOSE, Takahiro SHIBUYA ...
1998 年 44 巻 1 号 p.
P34
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Hironori KANDA, Yoshito KUMAGAI, Hiromi NAKAJIMA, Yasuhiro TAKENAKA, S ...
1998 年 44 巻 1 号 p.
P35
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Shiozi ISHIWATARI, Atsushi TAKEDA, Jinko SAWASHITA, Shoji OKADA, James ...
1998 年 44 巻 1 号 p.
P36
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
KenIchiro MINEGISHI, Sachiko SUZUKI, Toyozou KANEKO, Toru INOUE, Atsus ...
1998 年 44 巻 1 号 p.
P37
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Shigeki YAMANAKA, Ryuzo SAKAKIBARA, Yoshiro MATSUDA, Kiyoshi SOYANO, T ...
1998 年 44 巻 1 号 p.
P38
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Hiroyasu YAMAZAKI, Yoko ORITO, Sachiko KATAYAMA, Aki KAMEI, Takako YAM ...
1998 年 44 巻 1 号 p.
P39
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Yoshihisa KATO, Koichi HARAGUCHI, Koichi TOMIYASU, Tomoo SHIBAHARA, Yo ...
1998 年 44 巻 1 号 p.
P40
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Yoshihisa KATO, Tomoo SHIBAHARA, Koichi HARAGUCHI, Hiroyuki SAITO, Yos ...
1998 年 44 巻 1 号 p.
P41
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Tissue Distribution of Methylsulfonyl Metabolites Derived from 2, 2', 4, 4'-, 3, 3', 4, 4'-and 2, 3', 4', 5-Tetrachlorobiphenyls in Rats (Proceedings of the 23rd Symposium on Toxicology and Environmental Health)
Koichi HARAGUCHI, Yoshihisa KATO, Ryohei KIMURA, Takashi ITOH, Yoshito ...
1998 年 44 巻 1 号 p.
P42
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Atsuko TAKAHASHI, Hiroshi ONO, Hideto JINNO, Nobumitsu HANIOKA, Tetsuj ...
1998 年 44 巻 1 号 p.
P43
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー
-
Katsuhiko SAIDO, D.L. DAUBARAS, T. KLEM, A.M. CHAKRABARTY
1998 年 44 巻 1 号 p.
P44
発行日: 1998/02/28
公開日: 2008/05/30
ジャーナル
フリー